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What Is a Liver Cell Transplant?

In liver cell transplantation, liver cells isolated from livers unsuitable for liver transplantation is injected to the recipient’s portal vein. This method does not require surgery and may be used as an alternative to liver transplantation in indicated patients.

When Is a Liver Cell Transplant Necessary?

  • 1) Acute Hepatic Failure
    This method can be used for patients with acute or chronic hepatic failure including fulminant hepatic failure as an alternative to or a temporary treatment before liver transplantation.
  • 2) Congenital Metabolic Disorders
    This method can be used for an ex vivo gene therapy where liver cells collected from a patient with a congenital metabolic disorder are properly treated to include missing genes and injected back to the patient.

Advantages

1. There is no need for surgery and treatment may be repeated as necessary.
2. May be used as an alternative to liver transplantation especially when donor organ is scarce.
3. The cost is low.

How to Separate Liver Cells