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재활의학과 김연희 교수

진료분야
뇌졸중, 퇴행성 뇌질환, 인지재활, 감각운동재활, 언어재활, 재활, 뇌손상, 감각, 혈관성 치매, 뇌질환, 뇌출혈, 뇌경색, 보톡스, 장애, 근경직, 안면마비, 심장재활, 삼킴
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진료일정 09 月
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본원외래 본원클리닉 본원육아상담 암병원외래 암병원클리닉 암병원육아상담

학력

학력
1996.02 연세대학교 대학원 의학과 (박사)
1990.02 연세대학교 대학원 의학과 (석사)
1982.02 연세대학교 의과대학 졸업 (의학사)

경력

경력
2018.01 ~현재 대한민국 의학한림원 정회원
2016.01 ~현재 건강보험심사평가원 평가위원
2015.03 ~현재 성균관대학교 의료기기산업학과, 의료정보학과 겸임교수
2012.03 ~현재 성균관대학교 융합의과학과 겸임교수
2012.01 ~현재 보건복지부 권역심뇌혈관질환센터 운영평가위원
2003.05 ~현재 성균관의대 삼성서울병원 재활의학과 교수(뇌신경재활전문)
2014.03 ~ 2019.03 삼성서울병원 심뇌혈관병원 예방재활센터 센터장
2011.08 ~ 2017.07 한국연구재단 기초연구본부 의약학단 전문위원
2005.03 ~ 2012.02 성균관대학교 대학원 인지과학 협동과정 겸임교수
2005.09 ~ 2011.10 성균관의대 삼성서울병원 재활의학과장 및 주임교수
2002.03 ~ 2003.04 포천중문의대 분당차병원 재활의학과장 역임
1992.09 ~ 2002.02 전북대학교 의과대학 재활의학과 주임교수 및 과장 역임
1996.07 ~ 1998.06 미국 NorthWestern 대학 연구교수(인지신경학)
1986.03 ~ 1992.08 전주 예수병원 재활의학과 주임과장 역임

연구분야

연구분야
초발 급성뇌졸중 환자의 장애예방과 삶의 질 향상을 위한 전향적 추적조사 연구
뇌졸중은 약 80%에서 신경증상이 남게 되며, 40%정도에서 여생동안 장애가 남습니다. 이러한 초발 뇌졸중 환자의 장기적인 기능수준과 삶의 질에 영향을 미칠 수 있는 인자들을 파악하고 이를 개선할 수 있는 정책 개발 등을 목적으로 전국의 9개 기관을 총괄하여 10년간 시행되는 코호트 연구입니다.
파킨슨병 환자의 보행동결을 호전시킬 수 있는 뇌자극 기법 개발
보행동결 현상은 파킨슨환자에서 약물치료에 잘 반응하지 않는 난치성 증상이며, 경두개자기자극 및 경두개전기자극 등 비침습뇌자극 기법을 사용하여 이를 호전시킬 수 있는 치료적 기법을 연구합니다.
인지신경망 가소성 영상 및 증진 기법 연구
뇌졸중과 뇌손상 등 뇌질환 환자들에서 기능자기공명영상, 확산텐서영상, 뇌파도 등 기능영상을 복합적으로 사용하여 인지기능에 관련된 신경망을 영상화하고 특히 뇌질환 후 인지신경망의 회복 시 가소적인 변화 상태를 파악하며 비침습뇌자극 기법을 이용하여 인지신경망 회복을 증진시킬 수 있는 방법을 개발합니다. 작업기억력, 시공간지각기능, 언어기능 등을 대상으로 연구가 이루어집니다.
뇌졸중 후 신경회복 증진을 위한 복합 비침습뇌자극 기법 연구
신경가소성은 뇌신경 재활의 원리로서 뇌손상 환자의 성공적인 재활은 회복 과정 중 나타나는 가소적 변화의 효과적인 관리에 달려있다고 할 수 있습니다. 신경가소성의 기전을 규명함으로써 뇌손상 후 신경가소성을 극대화하고 성공적인 뇌기능 회복을 달성할 수 있는 기법을 개발하는 것을 목표로 연구를 진행하고 있으며, 이를 위해 신경영상과 비침습 뇌자극을 복합적으로 활용하고 있습니다. 신경영상은 뇌의 구조적, 기능적 특성을 가시화하는 방법으로서, 특히 기능자기공명영상, 확산텐서영상, 뇌전도, 기능근적외선 분광기 등의 기능적 신경영상을 이용하여 신경가소성에 따른 뇌의 변화를 가시화하고 뇌기능 회복의 원리를 밝힐 수 있습니다. 비침습 뇌자극은 경두개를 통해 전류를 흘려주어 뇌의 활성 변화를 유도하는 방법으로서, 반복 경두개 자기자극, 경두개 직류자극 등을 이용하여 신경가소성을 조절하여 뇌기능을 증진시킬 수 있습니다.

학회활동

학회활동
2018.03 ~ 현재 대한민국의학 한림원 정회원
2017.03 ~ 현재 대한임상노인의학회 부회장
2013.01 ~ 현재 World Federation of Neurorehabilitation
2010.01 ~ 현재 Society for Neuroscience 정회원
2005.01 ~ 현재 Organization of Human Brain Mapping 정회원
2015.03 ~ 2017.03 대한뇌신경재활학회 회장
2013.03 ~ 2014.03 대한신경조절학회 회장, 이사
2004.11 ~ 2006.11 대한뇌기능매핑학회 이사장

수상이력

수상이력
2016.10 대한재활의학회 신정순 학술상
2015.12 보건복지부장관 표창
2015.06 ISPRM 2015 등 국제학회 다수 우수 포스터상
2015.04 한국여의사회 JW 중외학술대상
2014.08 성균관대학교 교육영역 우수 교수
2014.01 뉴스메이커 ‘2014 한국을 이끄는 혁신리더’ 수상
2009.12 교육과학기술부장관상 국가연구기술 우수성과패
2008.04 The 3rd International Conference on Intracranial Artherosclerosis 등 국내외 학수 다수 우수포스터상
2007.11 대한뇌기능매핑학회 지맨스뇌기능매핑학술상
2005.10 대한재활의학회 학술상(2005년, 2002년, 2000년, 1997년)
논문
  • J Clin Neurol. 2019 Jan;15(1):54-61. Impact of Functional Status on Noncardioembolic Ischemic Stroke Recurrence Within 1 Year: The Korean Stroke Cohort for Functioning and Rehabilitation Study Min-Su Kim1, Min Cheol Joo, Min Kyun Sohn, Jongmin Lee, Deog Young Kim, Sam-Gyu Lee, Yong-Il Shin, Soo-Yeon Kim, Gyung-Jae Oh, Yang-Soo Lee, Eun Young Han, Junhee Han, Jeonghoon Ahn, Won Hyuk Chang, Yun-Hee Kim.
    View PubMed
  • NeuroRehabilitation. 2019;44(1):25-35. doi: 10.3233/NRE-182550. Neuroplastic and motor behavioral changes after intermanual transfer training of non-dominant hand: A prospective fMRI study. Jung D11, Park JW2, Kim YH3, You JSH1.
    View PubMed
  • Stroke, 2019, in press Training for Walking Efficiency with a Wearable Hip-assist Robot in Stroke Patients: A Pilot Randomized Controlled Trial. Hwang-Jae Lee1, Su-Hyun Lee, Keehong Seo, Minhyung Lee, Won Hyuk Chang, Byung-Ok Choi, Gyu-Ha Ryu, and Yun-Hee Kim.
  • International Journal of Gerontology, 2019, (13)139-143. Gender Differences in the Biomechanical and Physiological Properties of Gait in the Older Adults. Hwang-Jae Lee1, Dong-Sung Choi, Seung Yeol Lee, Won Hyuk Chang, Youngtaek Kim, Yun-Hee Kim.
  • Neural Plasticity, Apr 7;2019:3826495. doi: 10.1155/2019/3826495. Different Brain Connectivity between Responders and Nonresponders to Dual-Mode Noninvasive Brain Stimulation over Bilateral Primary Motor Cortices in Stroke Patients Jungsoo Lee1, Ahee Lee, Heegoo Kim, Mina Shin, Sang Moon Yun, YoungJin Jung, Won Hyuk Chang, Yun-Hee Kim.
    View PubMed
  • Journal of Alternative and Complementary Medicine, 2018, 24(5): 463-471. Efficacy of Hippotherapy Versus Pharmacotherapy in Attention-Deficit/Hyperactivity Disorder: A Randomized Clinical Trial Yun hye Oh1, Yoo-Sook Joung, Byongsu Jang, Jae Hyun Yoo, Jihye Song, Jiwon Kim, Kiho Kim, Seonwoo Kim, Jiyoung Lee, Hye-Yeon Shin, Jeong-Yi Kwon, Yun-Hee Kim, Bumseok Jeong.
    View PubMed
  • J Rehabil Med. 2018 Sep 28;50(9):800-805. doi: 10.2340/16501977-2373. Prediction for return to driving after the first-ever stroke in Korea: The KOSCO study. Jee S11, Sohn MK, Lee J, Kim DY, Lee SG, Shin YI, Oh GJ, Lee YS, Joo MC, Han EY, Kim YH.
    View PubMed
  • Brain & Neurorehabilitation, 11.2 (2018). Short-Term Effects of Intensive Inpatient Rehabilitation in Patients with Brain Tumor: a Single-Center Experience. Hyo Sun Lee1, Seungmi Yeo, Yun-Hee Kim, Won Hyuk Chang.
    View PubMed
  • Int J Mol Sci. 2018 Oct 12;19(10). pii: E3131. doi: 10.3390/ijms19103131. Relationship between Serum BDNF Levels and Depressive Mood in Subacute Stroke Patients: A Preliminary Study. Chang WH11, Shin MA2, Lee A3, Kim H4, Kim YH5,6.
    View PubMed
  • BMC Geriatr. 2018 Sep 29;18(1):230. doi: 10.1186/s12877-018-0921-1. A wearable hip-assist robot reduces the cardiopulmonary metabolic energy expenditure during stair ascent in elderly adults: a pilot cross-sectional study. Kim DS11,2, Lee HJ1,2, Lee SH1, Chang WH1, Jang J3, Choi BO4, Ryu GH5, Kim YH6,7.
    View PubMed
  • Am J Phys Med Rehabil. 2018 Aug;97(8):557-564. doi: 10.1097/PHM.0000000000000916. Association Between Spasticity and Functional Impairments During the First Year After Stroke in Korea: The KOSCO Study. Shin YI11, Kim SY, Lee HI, Kim DY, Lee J, Sohn MK, Lee SG, Oh GJ, Lee YS, Joo MC, Han EY, Han J, Moon MH, Chang WH, Kim Y, Kim YH.
    View PubMed
  • Neural Plast. 2018 Feb 13;2018:1458061. doi: 10.1155/2018/1458061. eCollection 2018. Modulating Brain Connectivity by Simultaneous Dual-Mode Stimulation over Bilateral Primary Motor Cortices in Subacute Stroke Patients. Lee J11,2, Park E3, Lee A2, Chang WH1, Kim DS4, Shin YI5, Kim YH1,2.
    View PubMed
  • Brain Topogr. 2018 Jul;31(4):708-719. doi: 10.1007/s10548-018-0644-9. Epub 2018 Apr 18. Alteration and Role of Interhemispheric and Intrahemispheric Connectivity in Motor Network After Stroke. Lee J11,2, Park E3, Lee A2, Chang WH1, Kim DS4, Kim YH5,6.
    View PubMed
  • Hum Brain Mapp. 2018 Dec;39(12):4976-4986. doi: 10.1002/hbm.24338. Epub 2018 Aug 18. Differences in motor network dynamics during recovery between supra- and infra-tentorial ischemic strokes. Lee J11,2, Lee A2, Kim H2, Chang WH1, Kim YH1,2.
    View PubMed
  • Journal of Sport Rehabilitation, 2018, e-pub. Modulation of Cortical Activity Induced by High-Frequency Whole-body Vibration Exercise: An fNIRS Study. Dong-Sung Choi1, Hwang-Jae Lee, Yong-Il Shin, Ahee Lee, Hee-Goo Kim and Yun-Hee Kim
    View PubMed
  • Brain & Neurorehabilitation, 11.2 (2018). Selection of Head Turn Side on Pharyngeal Dysphagia in Hemiplegic Stroke Patients: a Preliminary Study. Hannah Lee1, Hyunwoo Rho, Hee-Jung Cheon, Su Mi Oh, Yun-Hee Kim, Won Hyuk Chang.
    View PubMed
  • PloS one, 2018, 13(1), e-pub. Changes in network connectivity during motor imagery and execution. Yun Kwan Kim1, Eunhee Park, Ahee Lee, Chang-Hwan Im, Yun-Hee Kim.
    View PubMed
  • Cognitive Systems Research, 2017, 44: 1-9. ?doi: 10.1016/j.cogsys.2017.02.001. Cross-association analysis of EEG and EMG signals according to movement intention state. Byeongnam Kim1, Laehyun Kim, Yun-Hee Kim, Sun K. Yoo.
    View PubMed
  • Arch Phys Med Rehabil. 2017 Jul;98(7):1283-1290. doi: 10.1016/j.apmr.2017.01.011. Epub 2017 Feb 11. Effect of Dual-mode and Dual-site Non-invasive Brain Stimulation on Freezing of Gait in Patients with Parkinson's disease. Chang WH11, Kim MS2, Park E1, Cho JW3, Youn J3, Kim YK1, Kim YH4.
    View PubMed
  • Neuroscience Letters, 2017, 653: 78-83. Real-time measurement of cerebral blood flow during and after repetitive transcranial magnetic stimulation: A near-infrared spectroscopy study. Park E11, Kang MJ2, Lee A3, Chang WH2, Shin YI4, Kim YH5.
    View PubMed
  • J Neuroeng Rehabil. 2017 Nov 28;14(1):123. doi: 10.1186/s12984-017-0333-z. Gait performance and foot pressure distribution during wearable robot-assisted gait in elderly adults. Lee SH11, Lee HJ1,2, Chang WH1, Choi BO3, Lee J4, Kim J4, Ryu GH5, Kim YH6,7.
    View PubMed
  • IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2017, 25(9): 1549-1557. doi: 10.1109/TNSRE.2017.2664801 A Wearable Hip Assist Robot Can Improve Gait Function and Cardiopulmonary Metabolic Efficiency in Elderly Adults Hwang-Jae Lee1, Suhyun Lee, Won Hyuk Chang, Keehong Seo, Youngbo Shim, Byung-Ok Choi, Gyu-Ha Ryu, Yun-Hee Kim (Corresponding author).
    View PubMed
  • Eur J Neurol. 2017 Oct;24(10):1290-1299. doi: 10.1111/ene.13377. Epub 2017 Aug 18. Recovery-related indicators of motor network plasticity according to impairment severity after stroke. Lee J11,2, Park E3, Lee A2, Chang WH1, Kim DS4, Kim YH1,2.
    View PubMed
  • Translation Stroke Research, 2017, 48(6): 1457-1462. Stroke Induces MSC Migration to Infarcted Brain Areas Via CXCR4 and C-Met Signaling. Oh Young Bang1, Gyeong Joon Moon, Dong Hee Kim, Ji Hyun Lee, Sooyoon Kim, Jeong Pyo Son, Yeon Hee Cho, Won Hyuk Chang, Yun-Hee Kim.
    View PubMed
  • Stroke, 2017, 39(9): 904-910. doi: 10.1161/STROKEAHA.116.015264 Association Between Brain-Derived Neurotrophic Factor Genotype and Upper Extremity Motor Outcome After Stroke Won Hyuk Chang1, Eunhee Park, Jungsoo Lee, Ahee Lee, Yun-Hee Kim.
    View PubMed
  • Neuroimage Clin. 2017 Apr 19;15:118-124. doi: 10.1016/j.nicl.2017.04.016. eCollection 2017. Synergistic but independent: The role of corticospinal and alternate motor fibers for residual motor output after stroke. Schulz R11, Park E2, Lee J2, Chang WH2, Lee A3, Kim YH4, Hummel FC5.
    View PubMed
  • Stroke. 2017 Oct;48(10):2805-2811. doi: 10.1161/STROKEAHA.117.016834. Epub 2017 Sep 13. Interactions Between the Corticospinal Tract and Premotor-Motor Pathways for Residual Motor Output After Stroke. Schulz R11, Park E1, Lee J1, Chang WH1, Lee A1, Kim YH1, Hummel FC2.
    View PubMed
  • Disabil Rehabil. 2017 May;39(9):904-910. doi: 10.3109/09638288.2016.1170214. Epub 2016 May 20. Long-term functional outcomes of patients with very mild stroke: does a NIHSS score of 0 mean no disability? An interim analysis of the KOSCO study Chang WH11, Sohn MK2, Lee J3, Kim DY4, Lee SG5, Shin YI6, Oh GJ7, Lee YS8, Joo MC9, Han EY10, Kim MS9, Jang SY11, Kim JH1, Kim YH1,12.
    View PubMed
  • J Aging Phys Act. 2017 Apr;25(2):247-253. doi: 10.1123/japa.2015-0325. Epub 2016 Oct 5. Age-Related Locomotion Characteristics in Association with Balance Function in Young, Middle-Aged, and Older Adults Lee HJ1, Chang WH, Hwang SH, Choi BO, Ryu GH, Kim YH.
    View PubMed
  • BMC Neurol. 2017 Apr 17;17(1):72. doi: 10.1186/s12883-017-0841-2. Big data and data repurposing - using existing data to answer new questions in vascular dementia research Doubal FN11, Ali M2, Batty GD3, Charidimou A4, Eriksdotter M5, Hofmann-Apitius M6, Kim YH7, Levine DA8, Mead G9, Mucke HAM10, Ritchie CW11, Roberts CJ12, Russ TC13, Stewart R14, Whiteley W15, Quinn TJ16.
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  • J Gynecol Oncol. 2017 Mar;28(2):e18. doi: 10.3802/jgo.2017.28.e18. Epub 2016 Dec 7. Computed tomography-based quantitative assessment of lower extremity lymphedema following treatment for gynecologic cancer Yoo JS11, Chung SH1, Lim MC2, Kim YJ3, Kim KG3, Hwang JH4, Kim YH5.
    View PubMed
  • Restor Neurol Neurosci. 2017;35(2):137-146. doi: 10.3233/RNN-160689. Repeated anodal transcranial direct current stimulation induces neural plasticity-associated gene expression in the rat cortex and hippocampus Kim MS11, Koo H1, Han SW1, Paulus W2, Nitsche MA2,3,4, Kim YH5, Yoon JA6, Shin YI6.
    View PubMed
  • Neurol Sci. 2017 Feb;38(2):241-247. doi: 10.1007/s10072-016-2749-9. Epub 2016 Oct 25. Corticospinal excitability in the non-dominant hand is affected by BDNF genotype Chang WH11, Hwang JM1, Uhm KE1, Pascual-Leone A2, Kim YH3,4.
    View PubMed
  • BMC Neurol. 2017 Jan 10;17(1):9. doi: 10.1186/s12883-016-0780-3. Factors associated with improvement or decline in cognitive function after an ischemic stroke in Korea: the Korean stroke cohort for functioning and rehabilitation (KOSCO) study Yoon JA11, Kim DY2, Sohn MK3, Lee J4, Lee SG5, Lee YS6, Han EY7, Joo MC8, Oh GJ8, Han J9, Park M1, Park KP10, Noh KH10, Chang WH11, Shin YI12,13, Kim YH14.
    View PubMed
  • Restor Neurol Neurosci. 2017;35(1):105-114. doi: 10.3233/RNN-160669. Dual-mode noninvasive brain stimulation over the bilateral primary motor cortices in stroke patients Cho JY11, Lee A2, Kim MS3, Park E1, Chang WH1, Shin YI4, Kim YH1,2.
    View PubMed
  • Brain Stimul. 2017 Jan - Feb;10(1):75-82. doi: 10.1016/j.brs.2016.08.005. Epub 2016 Aug 11. Effects of Bilateral Repetitive Transcranial Magnetic Stimulation on Post-Stroke Dysphagia Park E11, Kim MS2, Chang WH1, Oh SM1, Kim YK3, Lee A4, Kim YH5.
    View PubMed
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  • Stroke. 2005 Jun;36(6):1166-71. Epub 2005 May 12. Virtual reality-induced cortical reorganization and associated locomotor recovery in chronic stroke - An experimenter-blind randomized study You SH11, Jang SH, Kim YH, Hallett M, Ahn SH, Kwon YH, Kim JH, Lee MY.
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  • Neurosci Lett. 2004 Sep 2;367(2):181-5. Facilitative effect of high frequency subthreshold repetitive transcranial magnetic stimulation on complex sequential motor learning in humans Kim YH11, Park JW, Ko MH, Jang SH, Lee PK.
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  • Neuroreport. 2004 Aug 26;15(12):1899-902. Ipsilateral motor pathway confirmed by diffusion tensor tractography in a patient with schizencephaly Kim YH11, Jang SH, Han BS, Kwon YH, You SH, Byun WM, Park JW, Yoo WK.
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  • Arch Phys Med Rehabil. 2004 Aug;85(8):1351-3. Ipsilateral motor pathway confirmed by combined brain mapping of a patient with hemiparetic stroke: A case report Kim YH11, Jang SH, Byun WM, Han BS, Lee KH, Ahn SH.
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  • Yonsei Med J. 2004 Apr 30;45(2):241-6. Plastic changes of motor network after constraint-induced movement therapy Kim YH11, Park JW, Ko MH, Jang SH, Lee PK.
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  • Neuroreport. 2004 Mar 1;15(3):395-9. Cortical activation changes associated with motor recovery in patients with precentral knob infarct Jang SH11, Cho SH, Kim YH, Kwon YH, Byun WM, Lee SJ, Park SM, Chang CH.
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  • Restor Neurol Neurosci.?2004;22(2):59-63. The predictive value of cortical activation by passive movement for motor recovery in stroke patients Jang SH11,?Kim YH,?Chang Y,?Han BS,?Byun WM,?Chang CH.
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  • Neuroreport.?2003 Jul 18;14(10):1305-10. Cortical reorganization associated with motor recovery in hemiparetic stroke patients Jang SH11,?Kim YH,?Cho SH,?Chang Y,?Lee ZI,?Ha JS.
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  • Neuroreport. 2003 Jul 18;14(10):1329-32. Bilateral primary sensori-motor cortex activation of post-stroke mirror movements: an fMRI study Kim YH11, Jang SH, Chang Y, Byun WM, Son S, Ahn SH.
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