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재활의학과 김연희 교수

진료분야
뇌졸중, 퇴행성 뇌질환, 인지재활, 감각운동재활, 언어재활, 재활, 뇌손상, 감각, 혈관성 치매, 뇌질환, 뇌출혈, 뇌경색, 보톡스, 장애, 근경직, 안면마비, 심장재활, 삼킴
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진료일정 11 月
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본원외래 본원클리닉 본원육아상담 암병원외래 암병원클리닉 암병원육아상담

학력

학력
1996.02 연세대학교 대학원 의학과 (박사)
1990.02 연세대학교 대학원 의학과 (석사)
1982.02 연세대학교 의과대학 졸업 (의학사)

경력

경력
2018.01 ~현재 대한민국 의학한림원 정회원
2016.01 ~현재 건강보험심사평가원 평가위원
2015.03 ~현재 성균관대학교 의료기기산업학과, 의료정보학과 겸임교수
2012.03 ~현재 성균관대학교 융합의과학과 겸임교수
2012.01 ~현재 보건복지부 권역심뇌혈관질환센터 운영평가위원
2003.05 ~현재 성균관의대 삼성서울병원 재활의학과 교수(뇌신경재활전문)
2014.03 ~ 2019.03 삼성서울병원 심뇌혈관병원 예방재활센터 센터장
2011.08 ~ 2017.07 한국연구재단 기초연구본부 의약학단 전문위원
2005.03 ~ 2012.02 성균관대학교 대학원 인지과학 협동과정 겸임교수
2005.09 ~ 2011.10 성균관의대 삼성서울병원 재활의학과장 및 주임교수
2002.03 ~ 2003.04 포천중문의대 분당차병원 재활의학과장 역임
1992.09 ~ 2002.02 전북대학교 의과대학 재활의학과 주임교수 및 과장 역임
1996.07 ~ 1998.06 미국 NorthWestern 대학 연구교수(인지신경학)
1986.03 ~ 1992.08 전주 예수병원 재활의학과 주임과장 역임

연구분야

연구분야
초발 급성뇌졸중 환자의 장애예방과 삶의 질 향상을 위한 전향적 추적조사 연구
뇌졸중은 약 80%에서 신경증상이 남게 되며, 40%정도에서 여생동안 장애가 남습니다. 이러한 초발 뇌졸중 환자의 장기적인 기능수준과 삶의 질에 영향을 미칠 수 있는 인자들을 파악하고 이를 개선할 수 있는 정책 개발 등을 목적으로 전국의 9개 기관을 총괄하여 10년간 시행되는 코호트 연구입니다.
파킨슨병 환자의 보행동결을 호전시킬 수 있는 뇌자극 기법 개발
보행동결 현상은 파킨슨환자에서 약물치료에 잘 반응하지 않는 난치성 증상이며, 경두개자기자극 및 경두개전기자극 등 비침습뇌자극 기법을 사용하여 이를 호전시킬 수 있는 치료적 기법을 연구합니다.
인지신경망 가소성 영상 및 증진 기법 연구
뇌졸중과 뇌손상 등 뇌질환 환자들에서 기능자기공명영상, 확산텐서영상, 뇌파도 등 기능영상을 복합적으로 사용하여 인지기능에 관련된 신경망을 영상화하고 특히 뇌질환 후 인지신경망의 회복 시 가소적인 변화 상태를 파악하며 비침습뇌자극 기법을 이용하여 인지신경망 회복을 증진시킬 수 있는 방법을 개발합니다. 작업기억력, 시공간지각기능, 언어기능 등을 대상으로 연구가 이루어집니다.
뇌졸중 후 신경회복 증진을 위한 복합 비침습뇌자극 기법 연구
신경가소성은 뇌신경 재활의 원리로서 뇌손상 환자의 성공적인 재활은 회복 과정 중 나타나는 가소적 변화의 효과적인 관리에 달려있다고 할 수 있습니다. 신경가소성의 기전을 규명함으로써 뇌손상 후 신경가소성을 극대화하고 성공적인 뇌기능 회복을 달성할 수 있는 기법을 개발하는 것을 목표로 연구를 진행하고 있으며, 이를 위해 신경영상과 비침습 뇌자극을 복합적으로 활용하고 있습니다. 신경영상은 뇌의 구조적, 기능적 특성을 가시화하는 방법으로서, 특히 기능자기공명영상, 확산텐서영상, 뇌전도, 기능근적외선 분광기 등의 기능적 신경영상을 이용하여 신경가소성에 따른 뇌의 변화를 가시화하고 뇌기능 회복의 원리를 밝힐 수 있습니다. 비침습 뇌자극은 경두개를 통해 전류를 흘려주어 뇌의 활성 변화를 유도하는 방법으로서, 반복 경두개 자기자극, 경두개 직류자극 등을 이용하여 신경가소성을 조절하여 뇌기능을 증진시킬 수 있습니다.

학회활동

학회활동
2018.03 ~ 현재 대한민국의학 한림원 정회원
2017.03 ~ 현재 대한임상노인의학회 부회장
2013.01 ~ 현재 World Federation of Neurorehabilitation
2010.01 ~ 현재 Society for Neuroscience 정회원
2005.01 ~ 현재 Organization of Human Brain Mapping 정회원
2015.03 ~ 2017.03 대한뇌신경재활학회 회장
2013.03 ~ 2014.03 대한신경조절학회 회장, 이사
2004.11 ~ 2006.11 대한뇌기능매핑학회 이사장

수상이력

수상이력
2016.10 대한재활의학회 신정순 학술상
2015.12 보건복지부장관 표창
2015.06 ISPRM 2015 등 국제학회 다수 우수 포스터상
2015.04 한국여의사회 JW 중외학술대상
2014.08 성균관대학교 교육영역 우수 교수
2014.01 뉴스메이커 ‘2014 한국을 이끄는 혁신리더’ 수상
2009.12 교육과학기술부장관상 국가연구기술 우수성과패
2008.04 The 3rd International Conference on Intracranial Artherosclerosis 등 국내외 학수 다수 우수포스터상
2007.11 대한뇌기능매핑학회 지맨스뇌기능매핑학술상
2005.10 대한재활의학회 학술상(2005년, 2002년, 2000년, 1997년)
논문
  • J NEUROENG REHABIL 2020 10.1186/s12984-020-00777-0 Wearable hip-assist robot modulates cortical activation during gait in stroke patients a functional near-infrared spectroscopy study Lee1, SH; Lee, HJ; Shim, Y; Chang, WH; Choi, BO; Ryu, GH; Kim, YH
    View PubMed
  • NEURAL PLAST 2020 10.1155/2020/5742421 Differential Relationship between Microstructural Integrity in White Matter Tracts and Motor Recovery following Stroke Based on Brain-Derived Neurotrophic Factor Genotype Park1, E; Lee, J; Chang, WH; Lee, A; Hummel, FC; Kim, YH
    View PubMed
  • EUR J NEUROL 2020 10.1111/ene.14494 Differential early predictive factors for upper and lower extremity motor recovery after ischaemic stroke Lee1, J; Kim, H; Kim, J; Lee, HJ; Chang, WH; Kim, YH
    View PubMed
  • PSYCHIATRY INVESTIG 2020 10.30773/pi.2019.0225 Effects of Process-Based Cognitive Training on Memory in the Healthy Elderly and Patients with Mild Cognitive Impairment A Randomized Controlled Trial Shin1, M; Lee, A; Cho, AY; Son, M; Kim, YH
    View PubMed
  • J MED IMAG HEALTH IN 2020 10.1166/jmihi.2020.3061 Simultaneous Clustering and Classification of Function Recovery Patterns of Ischemic Stroke Kim1, H; Lee, M; Sohn, MK; Lee, J; Kim, DY; Lee, SG; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Han, J; Ahn, J; Chang, WH; Choi, JY; Kang, SH; Lee, DH; Kim, YT; Choi, MT; Kim, YH
    View PubMed
  • THER ADV NEUROL DISO 2020 10.1177/1756286420925679 Prediction of motor recovery using indirect connectivity in a lesion network after ischemic stroke Lee1, J; Park, E; Lee, A; Chang, WH; Kim, DS; Kim, YH
    View PubMed
  • STROKE 2020 10.1161/STROKEAHA.119.026829 Effect of Cognitive Reserve on Risk of Cognitive Impairment and Recovery After Stroke The KOSCO Study Shin1, M; Sohn, MK; Lee, J; Kim, DY; Lee, SG; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Han, EY; Han, J; Ahn, J; Chang, WH; Shin, MA; Choi, JY; Kang, SH; Kim, Y; Kim, YH
    View PubMed
  • PLoS One 2020 10.1371/journal.pone.0226324 Determining the cut-off score for the Modified Barthel Index and the Modified Rankin Scale for assessment of functional independence and residual disability after stroke Lee1, SY; Kim, DY; Sohn, MK; Lee, J; Lee, SG; Shin, YI; Kim, SY; Oh, GJ; Lee, YH; Lee, YS; Joo, MC; Lee, SY; Ahn, J; Chang, WH; Choi, JY; Kang, SH; Kim, I; Han, J; Kim, YH
    View PubMed
  • TOP STROKE REHABIL 2020 10.1080/10749357.2019.1711338 Development and validation of a prediction model for home discharge in patients with moderate stroke: The Korean stroke cohort for functioning and rehabilitation study Kim1, MS; Joo, MC; Sohn, MK; Lee, J; Kim, DY; Lee, SG; Shin, YI; Kim, SY; Oh, GJ; Lee, YS; Han, EY; Han, J; Ahn, J; Chang, WH; Kim, YH; Choi, JY; Kang, SH; Kim, YT
    View PubMed
  • STROKE 2019 10.1161/STROKEAHA.119.025950 Training for Walking Efficiency With a Wearable Hip-Assist Robot in Patients With Stroke: A Pilot Randomized Controlled Trial Lee1, HJ; Lee, SH; Seo, K; Lee, M; Chang, WH; Choi, BO; Ryu, GH; Kim, YH
    View PubMed
  • J SPORT REHABIL 2019 10.1123/jsr.2017-0012 Modulation of Cortical Activity by High-Frequency Whole-Body Vibration Exercise: An fNIRS Study Choi1, DS; Lee, HJ; Shin, YI; Lee, A; Kim, HG; Kim, YH
    View PubMed
  • BMJ OPEN 2019 10.1136/bmjopen-2018-028673 Factors influencing return to work after stroke: the Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) Study Han1, J; Lee, HI; Shin, YI; Son, JH; Kim, SY; Kim, DY; Sohn, MK; Lee, J; Lee, SG; Oh, GJ; Lee, YS; Joo, MC; Han, EY; Chang, WH; Kim, YH
    View PubMed
  • INT J GERONTOL 2019 10.6890/IJGE.201906_13(2).0008 Gender Differences in the Biomechanical and Physiological Properties of Gait in the Older Adults Lee1, HJ; Choi, DS; Lee, SY; Chang, WH; Kim, Y; Kim, YH
    View PubMed
  • Neural Plast 2019 10.1155/2019/3826495 Different Brain Connectivity between Responders and Nonresponders to Dual-Mode Noninvasive Brain Stimulation over Bilateral Primary Motor Cortices in Stroke Patients Lee1, J; Lee, A; Kim, H; Shin, M; Yun, SM; Jung, Y; Chang, WH; Kim, YH
    View PubMed
  • NeuroRehabilitation 2019 10.3233/NRE-182550 Neuroplastic and motor behavioral changes after intermanual transfer training of non-dominant hand: A prospective fMRI study Jung1, D; Park, JW; Kim, YH; You, JH
    View PubMed
  • J CLIN NEUROL 2019 10.3988/jcn.2019.15.1.54 Impact of Functional Status on Noncardioembolic Ischemic Stroke Recurrence Within 1 Year: The Korean Stroke Cohort for Functioning and Rehabilitation Study Kim1, MS; Joo, MC; Sohn, MK; Lee, J; Kim, DY; Lee, SG; Shin, YI; Kim, SY; Oh, GJ; Lee, YS; Han, EY; Han, J; Ahn, J; Chang, WH; Kim, YH
    View PubMed
  • HUM BRAIN MAPP 2018 10.1002/hbm.24338 Differences in motor network dynamics during recovery between supra- and infra-tentorial ischemic strokes Lee1, J; Lee, A; Kim, H; Chang, WH; Kim, YH
    View PubMed
  • J REHABIL MED 2018 10.2340/16501977-2373 PREDICTION OF RETURN TO DRIVING AFTER FIRST-EVER STROKE IN KOREA: THE KOSCO STUDY Jee1, S; Sohn, MK; Lee, J; Kim, DY; Lee, SG; Shin, Y; Oh, GJ; Lee, YS; Joo, MC; Han, EY; Kim, YH
    View PubMed
  • INT J MOL SCI 2018 10.3390/ijms19103131 Relationship between Serum BDNF Levels and Depressive Mood in Subacute Stroke Patients: A Preliminary Study Chang1, WH; Shin, MA; Lee, A; Kim, H; Kim, YH
    View PubMed
  • BMC Geriatr 2018 10.1186/s12877-018-0921-1 A wearable hip-assist robot reduces the cardiopulmonary metabolic energy expenditure during stair ascent in elderly adults: a pilot cross-sectional study Kim1, DS; Lee, HJ; Lee, SH; Chang, WH; Jang, J; Choi, BO; Ryu, GH; Kim, YH
    View PubMed
  • AM J PHYS MED REHAB 2018 10.1097/PHM.0000000000000916 Association Between Spasticity and Functional Impairments During the First Year After Stroke in Korea: The KOSCO Study Shin1, YI; Kim, SY; Lee, HI; Kim, DY; Lee, J; Sohn, MK; Lee, SG; Oh, GJ; Lee, YS; Joo, MC; Han, EY; Han, J; Moon, MH; Chang, WH; Kim, Y; Kim, YH
    View PubMed
  • BRAIN TOPOGR 2018 10.1007/s10548-018-0644-9 Alteration and Role of Interhemispheric and Intrahemispheric Connectivity in Motor Network After Stroke Lee1, J; Park, E; Lee, A; Chang, WH; Kim, DS; Kim, YH
    View PubMed
  • J ALTERN COMPLEM MED 2018 10.1089/acm.2017.0358 Efficacy of Hippotherapy Versus Pharmacotherapy in Attention-Deficit/Hyperactivity Disorder: A Randomized Clinical Trial Oh1, Y; Joung, YS; Jang, B; Yoo, JH; Song, J; Kim, J; Kim, K; Kim, S; Lee, J; Shin, HY; Kwon, JY; Kim, YH; Jeong, B
    View PubMed
  • Neural Plast 2018 10.1155/2018/1458061 Modulating Brain Connectivity by Simultaneous Dual- Mode Stimulation over Bilateral Primary Motor Cortices in Subacute Stroke Patients Lee1, J; Park, E; Lee, A; Chang, WH; Kim, DS; Shin, YI; Kim, YH
    View PubMed
  • PLoS One 2018 10.1371/journal.pone.0190715 Changes in network connectivity during motor imagery and executionChanges in network connectivity during motor imagery and execution Kim1, YK; Park, E; Lee, A; Im, CH; Kim, YH
    View PubMed
  • IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2017, 25(9): 1549-1557. doi: 10.1109/TNSRE.2017.2664801 A Wearable Hip Assist Robot Can Improve Gait Function and Cardiopulmonary Metabolic Efficiency in Elderly Adults Hwang-Jae Lee1, Suhyun Lee, Won Hyuk Chang, Keehong Seo, Youngbo Shim, Byung-Ok Choi, Gyu-Ha Ryu, Yun-Hee Kim (Corresponding author).
    View PubMed
  • Neuroimage Clin. 2017 Apr 19;15:118-124. doi: 10.1016/j.nicl.2017.04.016. eCollection 2017. Synergistic but independent: The role of corticospinal and alternate motor fibers for residual motor output after stroke. Schulz R11, Park E2, Lee J2, Chang WH2, Lee A3, Kim YH4, Hummel FC5.
    View PubMed
  • Stroke, 2017, 39(9): 904-910. doi: 10.1161/STROKEAHA.116.015264 Association Between Brain-Derived Neurotrophic Factor Genotype and Upper Extremity Motor Outcome After Stroke Won Hyuk Chang1, Eunhee Park, Jungsoo Lee, Ahee Lee, Yun-Hee Kim.
    View PubMed
  • J NEUROENG REHABIL 2017 10.1186/s12984-017-0333-z Gait performance and foot pressure distribution during wearable robot-assisted gait in elderly adults Lee1, SH; Lee, HJ; Chang, WH; Choi, BO; Lee, J; Kim, J; Ryu, GH; Kim, YH
    View PubMed
  • Transl Stroke Res 2017 10.1007/s12975-017-0538-2 Stroke Induces Mesenchymal Stem Cell Migration to Infarcted Brain Areas Via CXCR4 and C-Met Signaling Bang1, OY; Moon, GJ; Kim, DH; Lee, JH; Kim, S; Son, JP; Cho, YH; Chang, WH; Kim, YH
    View PubMed
  • EUR J NEUROL 2017 10.1111/ene.13377 Recovery-related indicators of motor network plasticity according to impairment severity after stroke Lee1, J; Park, E; Lee, A; Chang, WH; Kim, DS; Kim, YH
    View PubMed
  • STROKE 2017 10.1161/STROKEAHA.117.016834 Interactions Between the Corticospinal Tract and Premotor-Motor Pathways for Residual Motor Output After Stroke Schulz1, R; Park, E; Lee, J; Chang, WH; Lee, A; Kim, YH; Hummel, FC
    View PubMed
  • COGN SYST RES 2017 10.1016/j.cogsys.2017.02.001 Cross-association analysis of EEG and EMG signals according to movement intention state Kim1, B; Kim, L; Kim, YH; Yoo, SK
    View PubMed
  • NEUROSCI LETT 2017 10.1016/j.neulet.2017.05.039 Real-time measurement of cerebral blood flow during and after repetitive transcranial magnetic stimulation: A near-infrared spectroscopy study Park1, E; Kang, MJ; Lee, A; Chang, WH; Shin, YI; Kim, YH
    View PubMed
  • Disabil Rehabil. 2017 May;39(9):904-910. doi: 10.3109/09638288.2016.1170214. Epub 2016 May 20. Long-term functional outcomes of patients with very mild stroke: does a NIHSS score of 0 mean no disability? An interim analysis of the KOSCO study Chang WH11, Sohn MK2, Lee J3, Kim DY4, Lee SG5, Shin YI6, Oh GJ7, Lee YS8, Joo MC9, Han EY10, Kim MS9, Jang SY11, Kim JH1, Kim YH1,12.
    View PubMed
  • BMC Neurol. 2017 Apr 17;17(1):72. doi: 10.1186/s12883-017-0841-2. Big data and data repurposing - using existing data to answer new questions in vascular dementia research Doubal FN11, Ali M2, Batty GD3, Charidimou A4, Eriksdotter M5, Hofmann-Apitius M6, Kim YH7, Levine DA8, Mead G9, Mucke HAM10, Ritchie CW11, Roberts CJ12, Russ TC13, Stewart R14, Whiteley W15, Quinn TJ16.
    View PubMed
  • J Aging Phys Act. 2017 Apr;25(2):247-253. doi: 10.1123/japa.2015-0325. Epub 2016 Oct 5. Age-Related Locomotion Characteristics in Association with Balance Function in Young, Middle-Aged, and Older Adults Lee HJ1, Chang WH, Hwang SH, Choi BO, Ryu GH, Kim YH.
    View PubMed
  • Restor Neurol Neurosci. 2017;35(2):137-146. doi: 10.3233/RNN-160689. Repeated anodal transcranial direct current stimulation induces neural plasticity-associated gene expression in the rat cortex and hippocampus Kim MS11, Koo H1, Han SW1, Paulus W2, Nitsche MA2,3,4, Kim YH5, Yoon JA6, Shin YI6.
    View PubMed
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