삼성서울병원

Ko En
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비뇨의학과 이규성 교수

진료분야
전립선비대증, 과민성방광, 요실금, 만성간질성방광염, 여성골반장기탈출, 신경인성배뇨장애, 전립선레이저수술, 야간빈뇨, 여성비뇨의학질환
진료일정 04 月
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진료일정 05 月
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본원외래 본원클리닉 본원육아상담 암병원외래 암병원클리닉 암병원육아상담

학력

학력
1998.02 서울대학교 의과대학원 (의학박사)
1991.02 서울대학교 의과대학원 (의학석사)
1987.02 서울대학교 의과대학

경력

경력
2013.08 ~현재 삼성서울병원 장기이식센터 전문의
2007.10 ~현재 성균관대학교 의과대학 비뇨의학 교실 교수
1996.03 ~현재 삼성서울병원 비뇨의학과 Staff
2020.05 ~ 2024.01 삼성서울병원 연구부원장
2020.05 ~ 2024.01 삼성서울병원 미래의학연구원장
2018.03 ~ 2020.04 스마트헬스케어-의료기기센터장
2014.09 ~ 2020.03 성균관대학교 삼성융합의과학원 의료기기산업학과 학과장
2015.04 ~ 2019.03 삼성서울병원 비뇨의학과 과장 및 주임교수
2013.08 ~ 2017.12 삼성서울병원 의공학연구센터장
2014.01 ~ 2015.12 성균관대학교 의과대학 학생부학장
2012.10 ~ 2013.07 삼성서울병원 인력양성센터장
2010.09 ~ 2011.12 삼성서울병원 의료기기교육실장
2010.09 ~ 2011.12 삼성서울병원 의료기기부장
2009.09 ~ 2011.12 삼성서울병원 임상시험센터 의약품교육실장
2001.10 ~ 2007.09 성균관대학교 의과대학 비뇨의학교실 부교수
2006.01 ~ 2006.03 University of California, San Diego, USA 방문교수
2004.03 ~ 2005.02 삼성서울병원 비뇨의학과 의국장
2000.09 ~ 2002.02 Univ. of Virginia, Charlottesville, Virginia, U.S.A 방문교수
1997.03 ~ 2001.09 성균관대학교 의과대학 비뇨의학교실 조교수
1995.03 ~ 1996.02 삼성서울병원 비뇨의학과 전임의
1992.05 ~ 1995.04 충청남도 서산의료원 비뇨의학과 과장
1988.03 ~ 1992.02 서울대학교병원 (레지던트 과정)
1987.03 ~ 1988.02 서울대학교병원 (인턴과정)

연구분야

연구분야
광에너지를 이용한 배뇨장애 치료
배뇨기능은 신경계의 조절을 받기 때문에 신경질환은 다양한 형태의 배뇨장애를 유발 할 수 있다. 신경계의 활성-억제는 배뇨기능을 제어할 수 있으며 이를 위한 방법으로 전기자극이 사용되고 있으나 신경 특이성이 떨어지고 억제 기능이 어렵다는 단점이 있다. Optogenetics은 빛을 이용하여 생물의 신경활동을 정확하게 조절하는 기술로서 초기에는 빛에 반응하는 뇌신경세포와 시신경 세포를 레이져 빛 등을 이용하여 연구하였다. 정밀한 작동제어 및 빠르게 뉴런을 자극하여 행동을 이끌어 내는 것이 Optogenetics의 키포인트이며, Optogenetics에 관련된 많은 세포 및 티슈 등이 발견 되고 있으며 임상적인 사용처로는 특정파장을 산출 하는 섬유(화이버)형태의 의료기기로 파킨슨병 등 신경계 관련 질병에 적용할 수 있을 것이다. 또한 이 원리는 배뇨기능을 담당하는 신경계의 활성-억제를 통해 다양한 배뇨장애 치료에 응용이 가능하다.

학회활동

학회활동
2019.01 ~ 2020.12 대한비뇨의학회 회장
2015.01 ~ 2016.12 대한비뇨의학회 총무이사
2011.01 ~ 2013.12 대한배뇨장애요실금학회 회장
2008.01 ~ 2010.12 대한배뇨장애요실금학회 연구이사
2009.01 ~ 2010.10 대한비뇨의학회지 부편집인
2006.01 ~ 2007.12 대한배뇨장애요실금학회 총무이사
2004.01 ~ 2005.12 대한배뇨장애요실금학회 학술이사
2002.01 ~ 2003.12 대한내비뇨의학회 총무이사

수상이력

수상이력
2018.10 38th SIU Congress best Poster
2017.12 보건복지부 장관상
논문
  • ADV THER 2024 10.1007/s12325-024-02784-2 Treatment Patterns with Mirabegron and Antimuscarinics for Overactive Bladder: A Prospective, Registry Study in Taiwan and South Korea (FAITH) Oh, SJ; Cho, ST; Kuo, HC; Chou, ECL; Hsu, YC; Lee, KS; Hadi, F; Song, Y; Sumarsono, B
    View PubMed
  • INT J MOL SCI 2024 10.3390/ijms25020778 Potential Role of Macrophage Polarization in the Progression of Hunner-Type Interstitial Cystitis Ko, KJ; Kim, G; Sung, HH; Park, WY; Lee, KS
    View PubMed
  • SCI REP-UK 2023 10.1038/s41598-023-44894-x Recurrence after postoperative intravesical instillation therapy in Hunner type interstitial cystitis Ko, KJ; Koo, MJ; Bang, S; Byun, HJ; Kim, MJ; Kim, K; Lee, KS
    View PubMed
  • LUTS 2023 10.1111/luts.12505 Optimal endoscopic treatment and partial cystectomy with or without bladder augmentation for Hunner-type interstitial cystitis Yu, J; Lee, CU; Lee, KS; Ko, KJ
    View PubMed
  • PHARMACOL REV 2023 10.1124/pharmrev.121.000523 Current and Emerging Pharmacological Targets and Treatments of Urinary Incontinence and Related Disorders Michel, MC; Cardozo, L; Chermansky, CJ; Cruz, F; Igawa, Y; Lee, KS; Sahai, A; Wein, AJ; Andersson, KE
    View PubMed
  • INT NEUROUROL J 2023 10.5213/inj.2346022.011 A Randomized, Double-Blind, Placebo-Controlled, Bridging Study to Evaluate the Efficacy and Safety of Vibegron in Treating Korean Patients With Overactive Bladder Shin, JH; Jeong, SJ; Kim, SO; Oh, CY; Chung, KJ; Shin, DG; Kim, TH; Kwon, J; Shin, JH; Bae, WJ; Lee, KS; Choo, MS
    View PubMed
  • NEUROUROL URODYNAM 2023 10.1002/nau.25190 A treatment prediction strategy for overactive bladder using a machine learning algorithm that utilized data from the FAITH study Hadi, F; Sumarsono, B; Lee, KS; Oh, SJ; Cho, ST; Hsu, YC; Rasner, P; Jenkins, C; Fisher, H
    View PubMed
  • TOXINS 2023 10.3390/toxins15050338 Retrospective Observational Study of Treatment Patterns and Efficacy of onabotulinumtoxinA Therapy in Patients with Refractory Overactive Bladder in Clinical Practice Ko, KJ; Lee, KS
    View PubMed
  • ACS NANO 2023 10.1021/acsnano.3c00755 Wireless, Fully Implantable and Expandable Electronic System for Bidirectional Electrical Neuromodulation of the Urinary Bladder Lee, JH; Jang, TM; Shin, JW; Lim, BH; Rajaram, K; Han, WB; Ko, GJ; Yang, SM; Han, SK; Kim, DJ; Kang, HS; Lim, JH; Lee, KS; Park, E; Hwang, SW
    View PubMed
  • APPL SCI-BASEL 2023 10.3390/app13042430 Optimization Framework for Temporal Interference Current Tibial Nerve Stimulation in Tibial Nerves Based on In-Silico Studies Kim, E; Ye, EB; Lee, JH; Kim, T; Choi, D; Lee, KYS; Park, S
    View PubMed
  • INT NEUROUROL J 2022 10.5213/inj.2244146.073 A Multicenter, Open-Label, Observational Study Evaluating the Quality of Life After Using a Hydrophilic-Coated Catheter (SpeediCath) With Self-Intermittent Catheterization Ko, KJ; Choo, MS; Kim, SO; Kim, JH; Chung, KJ; Yoo, ES; Kim, MK; Cho, WJ; Choi, JB; Lee, J; Lee, KS
    View PubMed
  • INT J UROL 2022 10.1111/iju.15083 The Asia-Pacific AMS800 artificial urinary sphincter consensus statement Chung, E; Liao, L; Kim, JH; Wang, Z; Kitta, T; Lin, ATL; Lee, KS; Ye, LF; Chu, P; Kaiho, Y; Takei, M; Jiang, H; Lee, J; Masuda, H; Tse, V
    View PubMed
  • INT NEUROUROL J 2022 10.5213/inj.2142408.204 A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome Ko, KJ; Byun, HJ; Bang, S; Lee, KS
    View PubMed
  • MEDICINE 2022 10.1097/MD.0000000000030091 Factors associated with quality of life in patients with benign prostatic hyperplasia, 2009-2016 Park, S; Lee, KS; Choi, M; Lee, M
    View PubMed
  • IEEE ACCESS 2022 10.1109/ACCESS.2022.3198980 Fabrication of a Flexible Three-Dimensional Hybrid Directional Lead for Deep Brain Stimulation and Control of Micturition Reflex in Rats Ju, C; Park, E; Ye, E; Kim, YG; Kim, T; Kang, M; Shon, YM; Lee, KS; Park, SM
    View PubMed
  • QUAL LIFE RES 2022 10.1007/s11136-022-03183-2 The impact of Hunner lesion-type interstitial cystitis/bladder pain syndrome on health-related quality of life and the effects of transurethral ablation Ko, KJ; Lim, J; Yu, J; Kang, D; Cho, J; Lee, KS
    View PubMed
  • INT NEUROUROL J 2022 10.5213/inj.2142382.191 Efficacy and Safety of DA-8010, a Novel M3 Antagonist, in Patients With Overactive Bladder: A Randomized, Double-Blind Phase 2 Study Son, HS; Oh, CY; Choo, MS; Kim, HG; Kim, JC; Lee, KS; Shin, DG; Cho, SY; Jeong, SJ; Seo, JT; Yoon, H; Moon, HS; Kim, JH
    View PubMed
  • INVESTIG CLIN UROL 2022 10.4111/icu.20210434 Feasibility of a deep learning-based diagnostic platform to evaluate lower urinary tract disorders in men using simple uroflowmetry Bang, S; Tukhtaev, S; Ko, KJ; Han, DH; Baek, M; Jeon, HG; Cho, BH; Lee, KS
    View PubMed
  • CLIN COSMET INV DERM 2022 10.2147/CCID.S344284 The usefulness of patient-specific 3D nasal silicone implant using 3D design and order form Lee, I; Ohba, N; Lee, H; Lee, KS; Lee, M
    View PubMed
  • NEUROUROL URODYNAM 2021 10.1002/nau.24776 Mirabegron has longer treatment persistence than antimuscarinics: Real-world data from a Korean national cohort database Lee, KS; Park, H; Kang, D; Byun, HJ; Foo, CY; Hadi, FA; Kim, S; Cho, J
    View PubMed
  • INT NEUROUROL J 2021 10.5213/inj.2040314.157 Comparison of Efficacy of Different Surgical Techniques for Benign Prostatic Obstruction Yu, J; Jeong, BC; Jeon, SS; Lee, SW; Lee, KS
    View PubMed
  • MOL PHARMACOL 2021 10.1124/molpharm.120.000106 Identification and Characterization of a Novel Large-Conductance Calcium-Activated Potassium Channel Activator, CTIBD, and Its Relaxation Effect on Urinary Bladder Smooth Muscle Lee1, N; Lim, BH; Lee, KS; Shin, J; Pagire, HS; Pagire, SH; Ahn, JH; Lee, SW; Kang, TM; Park, CS
    View PubMed
  • IEEE T BIO-MED ENG 2021 10.1109/TBME.2020.2995841 An Efficient Noninvasive Neuromodulation Modality for Overactive Bladder Using Time Interfering Current Method Lee1, J; Park, E; Kang, W; Kim, Y; Lee, KS; Park, SM
    View PubMed
  • COMPUT METH PROG BIO 2021 10.1016/j.cmpb.2020.105819 Automatic stenosis recognition from coronary angiography using convolutional neural networks Moon1, JH; Lee, DY; Cha, WC; Chung, MJ; Lee, KS; Cho, BH; Choi, JH
    View PubMed
  • ADV THER 2020 10.1007/s12325-020-01517-5 Mirabegron Add-On Therapy to Tamsulosin in Men with Overactive Bladder Post Hoc Analyses of Efficacy from the MATCH Study Kakizaki1, H; Lee, KS; Katou, D; Yamamoto, O; Sumarsono, B; Uno, S; Yamaguchi, O
    View PubMed
  • SCI REP-UK 2020 10.1038/s41598-020-76987-2 The long-lasting post-stimulation inhibitory effects of bladder activity induced by posterior tibial nerve stimulation in unanesthetized rats Park1, E; Lee, JW; Kim, T; Kang, MN; Cho, BH; Lee, JH; Park, SM; Lee, KS
    View PubMed
  • SCI ADV 2020 10.1126/sciadv.abc9675 Expandable and implantable bioelectronic complex for analyzing and regulating real-time activity of the urinary bladder Jang1, TM; Lee, JH; Zhou, HL; Joo, J; Lim, BH; Cheng, HY; Kim, SH; Kang, IS; Lee, KS; Park, E; Hwang, SW
    View PubMed
  • NEUROUROL URODYNAM 2020 10.1002/nau.24505 A multicenter prospective study for overactive bladder patient treatment satisfaction with mirabegron after being unsatisfied with antimuscarinic therapy (FAVOR study) Ko1, KJ; Choo, MS; Chang, YS; Kim, JC; Lee, KS
    View PubMed
  • LUTS 2020 10.1111/luts.12339 Cardiovascular safety of mirabegron add-on therapy to tamsulosin for the treatment of overactive bladder in men with lower urinary tract symptoms A post hoc analysis from theMATCHstudy Katoh1, T; Kakizaki, H; Lee, KS; Ishida, K; Katou, D; Yamamoto, O; Jong, JJ; Sumarsono, B; Uno, S; Yamaguchi, O
    View PubMed
  • WORLD J UROL 2020 10.1007/s00345-020-03417-3 Impact of COVID-19 on medical education introducinghomo digitalis Gravas1, S; Ahmad, M; Hernandez-Porras, A; Furriel, F; Alvarez-Maestro, M; Kumar, A; Lee, KS; Azodoh, E; Mburugu, P; Sanchez-Salas, R; Bolton, D; Gomez, R; Klotz, L; Kulkarni, S; Tanguay, S; Elliott, S; de la Rosette, J
    View PubMed
  • EUR UROL FOCUS 2020 10.1016/j.euf.2019.10.019 Mirabegron Add-on Therapy to Tamsulosin for the Treatment of Overactive Bladder in Men with Lower Urinary Tract Symptoms A Randomized, Placebo -controlled Study (MATCH) Kakizaki1, H; Lee, KS; Yamamoto, O; Jong, JJ; Katou, D; Sumarsono, B; Uno, S; Yamaguchi, O
    View PubMed
  • INVESTIG CLIN UROL 2020 10.4111/icu.2020.61.3.304 Changes in uroplakin expression in the urothelium of patients with ulcerative interstitial cystitis/bladder pain syndrome Cho1, KJ; Lee, KS; Choi, JB; Koh, JS; Kim, JC
    View PubMed
  • PLoS One 2020 10.1371/journal.pone.0233531 Effectiveness of electrical stimulation on nerve regeneration after crush injury: Comparison between invasive and non-invasive stimulation Ju1, C; Park, E; Kim, T; Kim, T; Kang, M; Lee, KS; Park, SM
    View PubMed
  • EUR UROL 2020 Comparison of the Efficacy Between Transurethral Coagulation and Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients: A Prospective Randomized Controlled Trial Ko1, KJ; Cho, WJ; Lee, YS; Choi, J; Byun, HJ; Lee, KS
    View PubMed
  • J CLIN MED 2020 10.3390/jcm9040895 Unmet Medical Needs of Patients with Benign Prostate Enlargement Lee1, M; Park, S; Choi, M; Lee, KS
    View PubMed
  • INT J UROL 2020 10.1111/iju.14234 Clinical guidelines for interstitial cystitis/bladder pain syndrome Homma1, Y; Akiyama, Y; Tomoe, H; Furuta, A; Ueda, T; Maeda, D; Lin, AT; Kuo, HC; Lee, MH; Oh, SJ; Kim, JC; Lee, KS
    View PubMed
  • LUTS 2020 10.1111/luts.12308 The prevalence of urinary incontinence in men and women aged 40 years or over in China, Taiwan and South Korea: A cross-sectional, prevalence-based study Sumarsono1, B; Jong, JJ; Wang, JY; Liao, LM; Lee, KS; Yoo, TK; Liu, SP; Chuang, YC
    View PubMed
  • J CLIN MED 2020 10.3390/jcm9010121 Relationship between Morbidity and Health Behavior in Chronic Diseases Lee1, M; Park, S; Lee, KS
    View PubMed
  • INVESTIG CLIN UROL 2019 10.4111/icu.2019.60.6.413 Current surgical management of pelvic organ prolapse: Strategies for the improvement of surgical outcomes Ko1, KJ; Lee, KS
    View PubMed
  • J UROLOGY 2019 10.1097/JU.0000000000000281 Efficacy and Safety of Tolterodine and Pilocarpine in Patients with Overactive Bladder Ko1, KJ; Kim, KH; Kim, SW; Kim, SO; Seo, JT; Choo, MS; Lee, JZ; Oh, SJ; Kim, HG; Min, KS; Kim, JH; Lee, KS
    View PubMed
  • ACS SENSORS 2019 10.1021/acssensors.9b00175 Development of Label-Free Colorimetric Assay for MERS-CoV Using Gold Nanoparticles Kim1, H; Park, M; Hwang, J; Kim, JH; Chung, DR; Lee, KS; Kang, M
    View PubMed
  • SUSTAINABILITY-BASEL 2019 10.3390/su11071948 What Are the Features of Successful Medical Device Start-Ups? Evidence from KOREA Lee1, M; Park, S; Lee, KS
    View PubMed
  • LUTS 2019 10.1111/luts.12220 Effect of lower urinary tract symptoms on the quality of life and sexual function of males in China, Taiwan, and South Korea: Subgroup analysis of a cross-sectional, population-based study Liao1, LM; Chuang, YC; Liu, SP; Lee, KS; Yoo, TK; Chu, R; Sumarsono, B; Wang, JY
    View PubMed
  • INVESTIG CLIN UROL 2019 10.4111/icu.2019.60.2.61 A new approach to urinary bladder control with optogenetics Park1, E; Lee, KS
    View PubMed
  • INTERNATIONAL NEUROUROLOGY JOURNAL 2019 10.5213/inj.1836176.088 A Korean Postmarketing Study Assessing the Effectiveness of OnabotulinumtoxinA for the Treatment of Neurogenic Detrusor Overactivity or Idiopathic Overactive Bladder Using a Validated Patient-Reported Outcome Measure Ko1, KJ; Jenkins, B; Patel, A; Lee, KS
    View PubMed
  • UROLOGY 2019 10.1016/j.urology.2018.11.012 Can the Penile Cuff Test Predict the Outcome of Holmium Laser Enucleation of the Prostate for Benign Prostatic Obstruction? Ko1, KJ; Na, JP; Lee, M; Ryu, GH; Lee, KS
    View PubMed
  • LUTS 2019 10.1111/luts.12193 Prevalence of overactive bladder in China, Taiwan and South Korea: Results from a cross-sectional, population-based study Chuang1, YC; Liu, SP; Lee, KS; Liao, L; Wang, JY; Yoo, TK; Chu, R; Sumarsono, B
    View PubMed
  • SCI REP-UK 2019 10.1038/s41598-018-36602-x Establishment and Validation of Extra-transitional Zone Prostate Specific Antigen Density (ETzD), a Novel Structure-based Parameter for Quantifying the Oncological Hazard of Prostates with Enlarged Stroma Kim1, JJ; Suh, YS; Kim, TH; Jeon, SS; Lee, HM; Choi, H; Kim, S; Lee, KS
    View PubMed
  • INTERNATIONAL NEUROUROLOGY JOURNAL 2018 10.5213/inj.1836246.123 Detecting Bladder Biomarkers for Closed-Loop Neuromodulation: A Technological Review Park1, E; Lee, JW; Kang, M; Cho, K; Cho, BH; Lee, KS
    View PubMed
  • SCI REP-UK 2018 10.1038/s41598-018-34781-1 Closed-type pre-treatment device for point-of-care testing of sputum Park1, HJ; Woo, A; Cha, JM; Lee, KS; Lee, MY
    View PubMed
  • WORLD J UROL 2018 10.1007/s00345-018-2329-0 The prevalence and risk factors of nocturia in China, South Korea, and Taiwan: results from a cross-sectional, population-based study Chow1, PM; Liu, SP; Chuang, YC; Lee, KS; Yoo, TK; Liao, LM; Wang, JY; Liu, M; Sumarsono, B; Jong, JJ
    View PubMed
  • BIOMED MICRODEVICES 2018 10.1007/s10544-018-0334-0 Silicon membrane filter designed by fluid dynamics simulation and near-field stress analysis for selective cell enrichment Jang1, YC; Park, HJ; Woo, A; Lee, KS; Moon, HS; Oh, JH; Lee, MY
    View PubMed
  • LUTS 2018 10.1111/luts.12168 Efficacy of Holmium Laser Transurethral Incision of the Prostate in Symptomatic Mild-to-Moderate Benign Prostate Enlargement Based on Preoperative Characteristics Suh1, YS; Ko, KJ; Kim, TH; Sung, HH; Lee, KS
    View PubMed
  • INQUIRY-J HEALTH CAR 2018 10.1177/0046958018791858 Social Network Analysis in the Legislative Process in the Korean Medical Device Industry Lee1, M; Yoon, K; Lee, KS
    View PubMed
  • INTERNATIONAL NEUROUROLOGY JOURNAL 2018 10.5213/inj.1836144.072 Recent Patient Health Monitoring Platforms Incorporating Internet of Things-Enabled Smart Devices Kang1, M; Park, E; Cho, BH; Lee, KS
    View PubMed
  • INTERNATIONAL NEUROUROLOGY JOURNAL 2018 10.5213/inj.1836152.076 Innovative Distribution Priorities for the Medical Devices Indus ry in the Fourth Industrial Revolution Lee1, M; Yoon, Y; Ryu, GH; Bok, HS; Yoon, K; Park, S; Lee, KS
    View PubMed
  • BJU INT 2018 10.1111/bju.14097 Therapeutic effects of endoscopic ablation in patients with Hunner type interstitial cystitis Ko1, KJ; Chung, H; Suh, YS; Lee, SW; Kim, TH; Lee, KS
    View PubMed
  • INTERNATIONAL NEUROUROLOGY JOURNAL 2018 10.5213/inj.1834904.452 Efficacy of an Alpha-Blocker for the Treatment of Nonneurogenic Voiding Dysfunction in Women: An 8-Week, Randomized, Double-Blind, Placebo-Controlled Trial Lee1, YS; Lee, KS; Choo, MS; Kim, JC; Lee, JG; Seo, JT; Lee, JZ; Lee, JY; Oh, SJ; Na, YG
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  • Int J Urol.?2005 Jun;12(6):544-7. A comparison of holmium : YAG laser with Lithoclast lithotripsy in ureteral calculi fragmentation Jeon SS11,?Hyun JH,?Lee KS.
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  • J Urol. 2003 Nov;170(5):2067-71. Alterations in voiding frequency and cystometry in the clomipramine induced model of endogenous depression and reversal with fluoxetine Lee KS11, Na YG, Dean-McKinney T, Klausner AP, Tuttle JB, Steers WD.
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  • Urology. 2002 Sep;60(3):411-4. Laparoscopic nephrectomy for tuberculous nonfunctioning kidney: Comparison with laparoscopic simple nephrectomy for other diseases Lee KS11, Kim HH, Byun SS, Kwak C, Park K, Ahn H.
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  • 없음 Depression and incontinence
  • 없음 MR imaging of acute penile fracture
  • J Endourol. 2000 Jun;14(5):433-7. Laparoscopic nephrectomy for nonfunctioning tuberculous kidney Kim HH11, Lee KS, Park K, Ahn H.
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