삼성서울병원

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재활의학과 장원혁 교수

진료분야
뇌손상, 뇌졸중, 뇌종양, 파킨슨병재활, 삼킴재활, 언어, 인지, 보톡스, 장애, 운동
진료일정 05 月
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진료일정 06 月
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본원외래 본원클리닉 본원육아상담 암병원외래 암병원클리닉 암병원육아상담

학력

학력
2012.02 고려대학교 대학원 의학과 (박사)
2005.02 연세대학교 대학원 의학과 (석사)
2000.02 연세대학교 의과대학 의학과 졸업 (학사)

경력

경력
2021.04 ~현재 성균관대학교 의과대학 삼성서울병원 재활의학과 교수
2015.04 ~ 2021.03 성균관대학교 의과대학 삼성서울병원 재활의학과 부교수
2014.09 ~ 2015.08 Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard medical school Research Fellow
2011.03 ~ 2015.03 성균관 의대 삼성서울병원 재활의학과 조교수
2010.03 ~ 2011.02 삼성서울병원 재활의학과 임상조교수
2009.03 ~ 2010.02 삼성서울병원 재활의학과 임상강사
2008.05 ~ 2009.02 신촌세브란스병원 재활의학과 임상강사
2005.04 ~ 2008.04 강화병원 재활의학과 과장 (공보의)
2001.03 ~ 2005.02 신촌세브란스병원 재활의학과 레지던트 과정 수료
2000.03 ~ 2001.02 신촌세브란스병원 인턴 과정 수료

연구분야

연구분야
비침습적 뇌자극을 이용한 기능 회복 촉진
뇌졸중, 뇌손상 등 뇌에 질환이 생긴 경우 운동기능, 인지기능, 언어기능 등 다양한 기능에 장애가 발생할 수 있습니다. 이러한 기능 장애를 치료하기 위해서 여러가지 재활치료 방법이 개발되어 사용되고 있으나 근본적 원인인 ‘뇌’ 자체를 직접 치료하는 방법에 대한 연구는 부족합니다. 비침습적 뇌자극은 수술적 치료없이 안전하고 효과적으로 뇌를 조절하여 뇌기능을 향상시킴으로써 다양한 기능적 호전을 기대할 수 있는 새로운 치료 방법입니다. 현재 안정성과 유효성이 입증되어 임상적으로 사용되고 있으나 그 효과가 제한적인 측면이 있습니다. 이에 본 연구는 향후 뇌신경재활분야의 선도적 미래의학으로 생각되는 비침습적 뇌자극의 치료 효과를 증진시키기 위한 연구입니다.

학회활동

학회활동
2017.01 ~ 현재 대한암재활학회 이사
2013.01 ~ 현재 한국재활승마학회 이사
2010.01 ~ 현재 Society for Neuroscience Membership
2010.01 ~ 현재 World Federation for NeuroRehabilitation Membership
2009.10 ~ 현재 대한뇌졸중학회 정회원
2009.03 ~ 현재 대한뇌기능매핑학회 정회원
2001.03 ~ 현재 대한뇌신경재활학회 이사
2001.03 ~ 현재 대한재활의학회 정회원

수상이력

수상이력
2017.11 재활의학 최우수연제상
2017.11 재활의학 학술상
2016.05 뇌졸중학회 Best Poster Presentation Award
2010.04 재활의학 우수포스터상
논문
  • CIRCULATION 2025 10.1161/CIRCULATIONAHA.124.070662 Risk of Atrial Fibrillation After Hemorrhagic Stroke: A Nationwide Cohort Study With Propensity Score Matching Kang, JH; Yoo, JE; Jeon, BJ; Im, SI; Kim, B; Chang, WH; Han, K; Shin, DW
    View PubMed
  • HEALTHCARE-BASEL 2025 10.3390/healthcare13010080 Increased Risk of End-Stage Kidney Disease After Traumatic Amputation: Nationwide Cohort Study Yoo, JE; Kim, B; Chang, WH; Lee, K; Jang, HR; Han, K; Shin, DW
    View PubMed
  • FRONT ENDOCRINOL 2025 10.3389/fendo.2024.1437860 Increased risk of type 2 diabetes after traumatic amputation: a nationwide retrospective cohort study Yoo, JE; Lee, DGY; Kim, B; Chang, WH; Jin, SM; Han, KYD; Shin, DW
    View PubMed
  • NUTRIENTS 2024 10.3390/nu16203461 The Significance of an Initial Controlling Nutritional Status Score in Predicting the Functional Outcome, Complications, and Mortality in a First-Ever Ischemic Stroke Choi, H; Jo, YJ; Sohn, MK; Lee, J; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Lee, YH; Kim, YH; Chang, WH; Kim, DY
    View PubMed
  • DIAGNOSTICS 2024 10.3390/diagnostics14182063 The Development of a Quantitative Disability Assessment Tool in Patients with Idiopathic Parkinson's Disease Seo, HG; Yun, SJ; Song, Y; Lee, HS; Kim, DH; Chang, WH
    View PubMed
  • HEALTHCARE-BASEL 2024 10.3390/healthcare12181859 Short-Term and Long-Term Risk of Diabetes Mellitus among Patients with Spinal Cord Injury: A Nationwide Retrospective Cohort Study Kim, S; Han, KD; Kim, B; Min, JH; Chang, WH; Cho, IY; Shin, DW
    View PubMed
  • TRIALS 2024 10.1186/s13063-024-08385-2 Efficacy of personalized repetitive transcranial magnetic stimulation based on functional reserve to enhance ambulatory function in patients with Parkinson's disease: study protocol for a randomized controlled trial Yun, SJ; Lee, HS; Kim, DH; Im, S; Yoo, YJ; Kim, NY; Lee, J; Kim, D; Park, HY; Yoon, MJ; Kim, YS; Chang, WH; Seo, HG
    View PubMed
  • GEN HOSP PSYCHIAT 2024 10.1016/j.genhosppsych.2024.03.006 Increased risk of developing depression in disability after spinal cord injury: A nationwide cohort study in South Korea Kwon, S; Han, KD; Kim, B; Jung, W; Chang, WH; Jeon, HJ; Shin, DW; Min, JH
    View PubMed
  • FRONT NEUROL 2024 10.3389/fneur.2024.1427142 Efficacy of personalized rTMS to enhance upper limb function in subacute stroke patients: a protocol for a multi-center, randomized controlled study Lee, HS; Kim, DH; Seo, HG; Im, S; Yoo, YJ; Kim, NY; Lee, J; Kim, D; Park, HY; Yoon, MJ; Kim, YS; Kim, H; Chang, WH
    View PubMed
  • J NEUROPHYSIOL 2024 10.1152/jn.00102.2024 Correlations in abnormal synergies between the upper and lower extremities across various phases of stroke Kim, D; Ko, SH; Han, J; Kim, YT; Kim, YH; Chang, WH; Shin, YI
    View PubMed
  • J NEUROPHYSIOL 2024 10.1152/jn.00067.2024 Evidence of the existence of multiple modules for the stroke-caused flexion synergy from Fugl-Meyer assessment scores Kim, D; Ko, SH; Han, J; Kim, YT; Kim, YH; Chang, WH; Shin, YI
    View PubMed
  • J PERS MED 2024 10.3390/jpm14070687 No Additional Effects of Sequential Facilitatory Cerebral and Cerebellar rTMS in Subacute Stroke Patients Lee, HS; Kim, S; Kim, H; Baik, SM; Kim, DH; Chang, WH
    View PubMed
  • BONE 2024 10.1016/j.bone.2024.117093 Risk of fracture among patients with spinal cord injury: A nationwide cohort study in South Korea Kim, S; Kim, B; Han, KD; Park, J; Yoo, JE; Choi, HL; Chang, WH; Cho, IY; Shin, DW
    View PubMed
  • J PERS MED 2024 10.3390/jpm14060610 Association between Height and Functional Outcomes of Patients 6 Months after a Stroke: A Multicenter Prospective Observational Cohort Study Kang, NY; Ko, SH; Shin, YI; Min, JH; Yun, MS; Sohn, MK; Lee, JM; Kim, DY; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, JH; Ahn, J; Kim, YH; Chang, WH
    View PubMed
  • STROKE 2024 10.1161/STROKEAHA.123.044953 Fracture Risk Among Stroke Survivors According to Poststroke Disability Status and Stroke Type Lee, DGY; Cho, IY; Chang, WH; Yoo, JE; Choi, HL; Park, J; Shin, DW; Han, KYD
    View PubMed
  • J AM HEART ASSOC 2024 10.1161/JAHA.123.033304 Risk of Heart Disease in Patients With Amputation: A Nationwide Cohort Study in South Korea Choi, HL; Yoo, JE; Kim, M; Kim, B; Park, J; Chang, WH; Lee, H; Han, K; Shin, DW
    View PubMed
  • MEDICINA-LITHUANIA 2024 10.3390/medicina60040559 Predictors of Burden for First-Ever Stroke Survivor's Long-Term Caregivers: A Study of KOSCO Lee, JW; Sohn, MK; Lee, J; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Han, J; Ahn, J; Kim, YH; Song, MK; Chang, WH
    View PubMed
  • AM J PHYS MED REHAB 2024 10.1097/PHM.0000000000002351 Incidence of Altered Level of Consciousness in Hemorrhagic Stroke Survivors Ko, N; Lee, HH; Sohn, MK; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Chang, WH; Lee, J; Kim, YH
    View PubMed
  • J AM HEART ASSOC 2024 10.1161/JAHA.123.032377 Long-Term Functional Outcome in Patients With Isolated Thalamic Stroke: The KOSCO Study Lee, HS; Sohn, MK; Lee, J; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Kim, DH; Kim, YH; Chang, WH
    View PubMed
  • EUR J NEUROL 2024 10.1111/ene.16194 Risk of Parkinson disease in stroke patients: A nationwide cohort study in South Korea Choi, HL; Ahn, JH; Chang, WH; Jung, W; Kim, BS; Han, K; Youn, J; Shin, DW
    View PubMed
  • J STROKE CEREBROVASC 2023 10.1016/j.jstrokecerebrovasdis.2023.107302 Predictors of quality of life at 6 months in patients with mild stroke: A prospective observational cohort study Kim, MS; Min, JH; Shin, YI; Sohn, MK; Lee, JM; Kim, DY; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, JH; Ahn, J; Kim, YH; Ko, SH; Chang, WH
    View PubMed
  • BMJ OPEN 2023 10.1136/bmjopen-2022-065298 Exoskeletal wearable robot on ambulatory function in patients with stroke: a protocol for an international, multicentre, randomised controlled study Chang, WH; Kim, TW; Kim, HS; Hanapiah, FA; Kim, DH; Kim, DY
    View PubMed
  • JAMA NETW OPEN 2023 10.1001/jamanetworkopen.2023.20873 Assessment of Disability and Depression Following Amputation Among Adults in Korea Jung, W; Kim, M; Jeon, HJ; Chang, WH; Yoo, JE; Han, K; Shin, DW
    View PubMed
  • FRONT NEUROL 2023 10.3389/fneur.2023.1130236 Clustering and prediction of long-term functional recovery patterns in first-time stroke patients Shin, S; Chang, WH; Kim, DY; Lee, J; Sohn, MK; Song, MK; Shin, YI; Lee, YS; Joo, MC; Lee, SY; Han, J; Ahn, J; Oh, GJ; Kim, YT; Kim, K; Kim, YH
    View PubMed
  • INT J STROKE 2023 10.1177/17474930231159779 Gender differences in mortality and long-term functional outcomes after first-ever ischemic stroke: A prospective cohort study Yun, SM; Shin, S; Chang, WH; Kim, DY; Lee, JM; Sohn, MK; Song, MK; Shin, YI; Lee, YS; Joo, MC; Lee, SY; Han, JH; Ahn, J; Oh, GJ; Kim, YH
    View PubMed
  • GUT LIVER 2023 10.5009/gnl220337 Pretransplant Functional Status Predicts Postoperative Morbidity and Mortality after Liver Transplantation in Patients with Cirrhosis Goh, MJ; Kim, J; Chang, WH; Sinn, DH; Gwak, GY; Paik, YH; Choi, MS; Lee, JH; Koh, KC; Paik, SW; Kim, JM; Kang, WS
    View PubMed
  • INT J ENV RES PUB HE 2023 10.3390/ijerph20010842 Increased Risk of Developing Depression in Disability after Stroke: A Korean Nationwide Study Choi, HL; Yang, KYJ; Han, KYD; Kim, B; Chang, WH; Kwon, S; Jung, WY; Yoo, JE; Jeon, HJ; Shin, DW
    View PubMed
  • FRONT AGING NEUROSCI 2023 10.3389/fnagi.2022.1059563 Relationship between lower limb muscle activity and cortical activation among elderly people during walking: Effects of fast speed and cognitive dual task Kim, J; Lee, JS; Lee, GHY; Chang, WH; Ko, MH; Yoo, WK; Ryu, GH; Kim, YH
    View PubMed
  • J PERS MED 2023 10.3390/jpm13010131 Factors Associated with Unplanned Transfer of Patients with Brain Tumor from Inpatient Rehabilitation Unit to Primary Acute Care Units Nam, GH; Chang, WH
    View PubMed
  • J CLIN MED 2022 10.3390/jcm11247343 A Smart Glove Digital System Promotes Restoration of Upper Limb Motor Function and Enhances Cortical Hemodynamic Changes in Subacute Stroke Patients with Mild to Moderate Weakness: A Randomized Controlled Trial Shin, S; Lee, HJ; Chang, WH; Ko, SH; Shin, YI; Kim, YH
    View PubMed
  • STROKE 2022 10.1161/STROKEAHA.121.038196 Understanding of the Lower Extremity Motor Recovery After First-Ever Ischemic Stroke Lee, HH; Sohn, MK; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Lee, YH; Chang, WH; Choi, SM; Lee, SK; Lee, J; Kim, YH
    View PubMed
  • JAMA NETW OPEN 2022 10.1001/jamanetworkopen.2022.33094 Multifaceted Assessment of Functional Outcomes in Survivors of First-time Stroke Shin, S; Lee, Y; Chang, WH; Sohn, MK; Lee, J; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Kim, YH
    View PubMed
  • J PERS MED 2022 10.3390/jpm12091505 Clinical Characteristics and Risk Factors of First-Ever Stroke in Young Adults: A Multicenter, Prospective Cohort Study Jo, YJ; Kim, DH; Sohn, MK; Lee, J; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Chang, WH; Kim, YH; Kim, DY
    View PubMed
  • INT J ENV RES PUB HE 2022 10.3390/ijerph19159612 Changes in Long-Term Functional Independence in Patients with Moderate and Severe Ischemic Stroke: Comparison of the Responsiveness of the Modified Barthel Index and the Functional Independence Measure Lee, EY; Sohn, MK; Lee, JM; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Lee, SY; Song, MK; Han, JH; Ahn, JH; Lee, YH; Chang, WH; Choi, SM; Lee, SK; Joo, MC; Kim, YH
    View PubMed
  • STROKE 2022 10.1161/STROKEAHA.121.036545 Circulating Extracellular Vesicles in Stroke Patients Treated With Mesenchymal Stem Cells: A Biomarker Analysis of a Randomized Trial Bang, OY; Kim, EH; Cho, YH; Oh, MJ; Chung, JW; Chang, WH; Kim, YH; Yang, SW; Chopp, M
    View PubMed
  • J PERS MED 2022 10.3390/jpm12050822 Personalized Approaches to Stroke: One Step Forward for Functional Recovery of Stroke Patients Chang, WH
    View PubMed
  • CEREBELLUM 2022 10.1007/s12311-022-01416-1 M1 and Cerebellar tDCS for MSA-C: a Double-Blind, Randomized, Sham-Controlled, Crossover Study Ahn, JH; Lee, D; Kim, M; Cho, JW; Chang, WH; Youn, J
    View PubMed
  • DISABIL REHABIL 2022 10.1080/09638288.2022.2074154 Effects of the home-based exercise program with an augmented reality system on balance in patients with stroke: a randomized controlled trial Lee, JI; Park, J; Koo, J; Son, M; Hwang, JH; Lee, JY; Chang, WH
    View PubMed
  • J PERS MED 2022 10.3390/jpm12030432 Whole Brain Hemodynamic Response Based on Synchrony Analysis of Brain Signals for Effective Application of HD-tDCS in Stroke Patients: An fNIRS Study Lee, G; Lee, J; Kim, J; Kim, H; Chang, WH; Kim, YH
    View PubMed
  • FRONT NEUROL 2022 10.3389/fneur.2022.804206 Multichannel Transcranial Direct Current Stimulation Combined With Treadmill Gait Training in Patients With Parkinson's Disease: A Pilot Study Na, Y; Kim, J; Lee, SH; Kim, J; Lee, J; Shin, SY; Chang, WH; Cho, JW; Kim, YH
    View PubMed
  • J PERS MED 2022 10.3390/jpm12030389 Post-Stroke Depression and Cognitive Aging: A Multicenter, Prospective Cohort Study Shin, M; Sohn, MK; Lee, J; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Lee, YH; Chang, WH; Shin, S; Choi, SM; Lee, SK; Kim, YH
    View PubMed
  • STROKE 2022 10.1161/STROKEAHA.121.034505 Efficacy of Intravenous Mesenchymal Stem Cells for Motor Recovery After Ischemic Stroke: A Neuroimaging Study Lee, J; Chang, WH; Chung, JW; Kim, SK; Lee, JS; Sohn, SI; Kim, YH; Bang, OY
    View PubMed
  • J PERS MED 2021 10.3390/jpm11060545 2021 Cerebrolysin Combined with Rehabilitation Enhances Motor Recovery and Prevents Neural Network Degeneration in Ischemic Stroke Patients with Severe Motor Deficits Chang1, WH; Lee, J; Shin, YI; Ko, MH; Kim, DY; Sohn, MK; Kim, J; Kim, YH
    View PubMed
  • NEUROLOGY 2021 10.1212/WNL.0000000000011440 2021 Efficacy and Safety of Intravenous Mesenchymal Stem Cells for Ischemic Stroke Chung1, JW; Chang, WH; Bang, OY; Moon, GJ; Kim, SJ; Kim, SK; Lee, JS; Sohn, SI; Kim, YH
    View PubMed
  • PLOS ONE 2021 10.1371/journal.pone.0246817 2021 Brain morphological and connectivity changes on MRI after stem cell therapy in a rat stroke model Son1, JP; Sung, JH; Kim, DH; Cho, YH; Kim, SJ; Chung, JW; Chang, WH; Kim, YH; Kim, EH; Moon, GJ; Bang, OY
    View PubMed
  • NEUROSCI LETT 2021 10.1016/j.neulet.2020.135424 2021 Optimal stimulation site for rTMS to improve motor function: Anatomical hand knob vs. hand motor hotspot Kim1, H; Kim, J; Lee, HJ; Lee, J; Na, Y; Chang, WH; Kim, YH
    View PubMed
  • NEUROREHAB NEURAL RE 2021 10.1177/15459683211070278 Multimodal Imaging Biomarker-Based Model Using Stratification Strategies for Predicting Upper Extremity Motor Recovery in Severe Stroke Patients Lee, J; Kim, H; Kim, J; Chang, WH; Kim, YH
    View PubMed
  • ARCH PHYS MED REHAB 2021 10.1016/j.apmr.2021.07.788 Status Of Dysphagia After Ischemic Stroke: A Korean Nationwide Study Ko, N; Lee, HH; Sohn, MK; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Lee, YH; Chang, WH; Choi, SM; Lee, SK; Lee, J; Kim, YH
    View PubMed
  • J PERS MED 2021 10.3390/jpm11111162 Relationship between the Corticospinal and Corticocerebellar Tracts and Their Role in Upper Extremity Motor Recovery in Stroke Patients Lee, J; Chang, WH; Kim, YH
    View PubMed
  • SCI REP-UK 2021 10.1038/s41598-021-01182-w A structured exercise to relieve musculoskeletal pain caused by face-down posture after retinal surgery: a randomized controlled trial Kim, AY; Hwang, S; Kang, SW; Shin, SY; Chang, WH; Kim, SJ; Noh, H
    View PubMed
  • INT J ENV RES PUB HE 2021 10.3390/ijerph182212072 Different Effects of Robot-Assisted Gait and Independent Over-Ground Gait on Foot Plantar Pressure in Incomplete Spinal Cord Injury: A Preliminary Study Bae, YH; Chang, WH; Fong, SSM
    View PubMed
  • J PERS MED 2021 10.3390/jpm11111137 Probable Factors Associated with Response to Mesenchymal Stem Cell Therapy in Stroke Patients: A Post Hoc Analysis of the STARTING-2 Trial Chang, WH; Lee, J; Chung, JW; Kim, YH; Bang, OY
    View PubMed
  • STROKE 2021 10.1161/STROKEAHA.120.032409 Revisiting the Proportional Recovery Model in View of the Ceiling Effect of Fugl-Meyer Assessment Lee, HH; Kim, DY; Sohn, MK; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Han, J; Ahn, J; Chang, WH; Kim, I; Choi, SM; Lee, J; Kim, YH
    View PubMed
  • DISABIL REHABIL 2021 10.1080/09638288.2021.1994660 Reliability and validity of the Korean version of the Functional Status Score for the ICU after translation and cross-cultural adaptation Do, JG; Suh, GY; Won, YH; Chang, WH; Hiser, S; Needham, DM; Chung, CR
    View PubMed
  • BMC GERIATR 2021 10.1186/s12877-021-02401-9 Correlation between cardiopulmonary metabolic energy cost and lower-limb muscle activity during inclined treadmill gait in older adults Kim, J; Lee, HJ; Lee, SH; Lee, J; Chang, WH; Ryu, GH; Kim, YH
    View PubMed
  • J NEUROENG REHABIL 2020 10.1186/s12984-020-00777-0 2020 Wearable hip-assist robot modulates cortical activation during gait in stroke patients a functional near-infrared spectroscopy study Lee1, SH; Lee, HJ; Shim, Y; Chang, WH; Choi, BO; Ryu, GH; Kim, YH
    View PubMed
  • NEURAL PLAST 2020 10.1155/2020/5742421 2020 Differential Relationship between Microstructural Integrity in White Matter Tracts and Motor Recovery following Stroke Based on Brain-Derived Neurotrophic Factor Genotype Park1, E; Lee, J; Chang, WH; Lee, A; Hummel, FC; Kim, YH
    View PubMed
  • EUR J NEUROL 2020 10.1111/ene.14494 2020 Differential early predictive factors for upper and lower extremity motor recovery after ischaemic stroke Lee1, J; Kim, H; Kim, J; Lee, HJ; Chang, WH; Kim, YH
    View PubMed
  • THER ADV NEUROL DISO 2020 10.1177/1756286420925679 2020 Prediction of motor recovery using indirect connectivity in a lesion network after ischemic stroke Lee1, J; Park, E; Lee, A; Chang, WH; Kim, DS; Kim, YH
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