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재활의학과 장원혁 교수

진료분야
뇌손상, 뇌졸중, 뇌종양, 파킨슨병재활, 삼킴재활, 언어, 인지, 보톡스, 장애, 운동
진료일정 04 月
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진료일정 05 月
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본원외래 본원클리닉 본원육아상담 암병원외래 암병원클리닉 암병원육아상담

학력

학력
2012.02 고려대학교 대학원 의학과 (박사)
2005.02 연세대학교 대학원 의학과 (석사)
2000.02 연세대학교 의과대학 의학과 졸업 (학사)

경력

경력
2021.04 ~현재 성균관대학교 의과대학 삼성서울병원 재활의학과 교수
2015.04 ~ 2021.03 성균관대학교 의과대학 삼성서울병원 재활의학과 부교수
2014.09 ~ 2015.08 Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard medical school Research Fellow
2011.03 ~ 2015.03 성균관 의대 삼성서울병원 재활의학과 조교수
2010.03 ~ 2011.02 삼성서울병원 재활의학과 임상조교수
2009.03 ~ 2010.02 삼성서울병원 재활의학과 임상강사
2008.05 ~ 2009.02 신촌세브란스병원 재활의학과 임상강사
2005.04 ~ 2008.04 강화병원 재활의학과 과장 (공보의)
2001.03 ~ 2005.02 신촌세브란스병원 재활의학과 레지던트 과정 수료
2000.03 ~ 2001.02 신촌세브란스병원 인턴 과정 수료

연구분야

연구분야
비침습적 뇌자극을 이용한 기능 회복 촉진
뇌졸중, 뇌손상 등 뇌에 질환이 생긴 경우 운동기능, 인지기능, 언어기능 등 다양한 기능에 장애가 발생할 수 있습니다. 이러한 기능 장애를 치료하기 위해서 여러가지 재활치료 방법이 개발되어 사용되고 있으나 근본적 원인인 ‘뇌’ 자체를 직접 치료하는 방법에 대한 연구는 부족합니다. 비침습적 뇌자극은 수술적 치료없이 안전하고 효과적으로 뇌를 조절하여 뇌기능을 향상시킴으로써 다양한 기능적 호전을 기대할 수 있는 새로운 치료 방법입니다. 현재 안정성과 유효성이 입증되어 임상적으로 사용되고 있으나 그 효과가 제한적인 측면이 있습니다. 이에 본 연구는 향후 뇌신경재활분야의 선도적 미래의학으로 생각되는 비침습적 뇌자극의 치료 효과를 증진시키기 위한 연구입니다.

학회활동

학회활동
2017.01 ~ 현재 대한암재활학회 이사
2013.01 ~ 현재 한국재활승마학회 이사
2010.01 ~ 현재 Society for Neuroscience Membership
2010.01 ~ 현재 World Federation for NeuroRehabilitation Membership
2009.10 ~ 현재 대한뇌졸중학회 정회원
2009.03 ~ 현재 대한뇌기능매핑학회 정회원
2001.03 ~ 현재 대한뇌신경재활학회 이사
2001.03 ~ 현재 대한재활의학회 정회원

수상이력

수상이력
2017.11 재활의학 최우수연제상
2017.11 재활의학 학술상
2016.05 뇌졸중학회 Best Poster Presentation Award
2010.04 재활의학 우수포스터상
논문
  • EUR J NEUROL 2024 10.1111/ene.16194 Risk of Parkinson disease in stroke patients: A nationwide cohort study in South Korea Choi, HL; Ahn, JH; Chang, WH; Jung, W; Kim, BS; Han, K; Youn, J; Shin, DW
    View PubMed
  • J STROKE CEREBROVASC 2023 10.1016/j.jstrokecerebrovasdis.2023.107302 Predictors of quality of life at 6 months in patients with mild stroke: A prospective observational cohort study Kim, MS; Min, JH; Shin, YI; Sohn, MK; Lee, JM; Kim, DY; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, JH; Ahn, J; Kim, YH; Ko, SH; Chang, WH
    View PubMed
  • BMJ OPEN 2023 10.1136/bmjopen-2022-065298 Exoskeletal wearable robot on ambulatory function in patients with stroke: a protocol for an international, multicentre, randomised controlled study Chang, WH; Kim, TW; Kim, HS; Hanapiah, FA; Kim, DH; Kim, DY
    View PubMed
  • JAMA NETW OPEN 2023 10.1001/jamanetworkopen.2023.20873 Assessment of Disability and Depression Following Amputation Among Adults in Korea Jung, W; Kim, M; Jeon, HJ; Chang, WH; Yoo, JE; Han, K; Shin, DW
    View PubMed
  • FRONT NEUROL 2023 10.3389/fneur.2023.1130236 Clustering and prediction of long-term functional recovery patterns in first-time stroke patients Shin, S; Chang, WH; Kim, DY; Lee, J; Sohn, MK; Song, MK; Shin, YI; Lee, YS; Joo, MC; Lee, SY; Han, J; Ahn, J; Oh, GJ; Kim, YT; Kim, K; Kim, YH
    View PubMed
  • INT J STROKE 2023 10.1177/17474930231159779 Gender differences in mortality and long-term functional outcomes after first-ever ischemic stroke: A prospective cohort study Yun, SM; Shin, S; Chang, WH; Kim, DY; Lee, JM; Sohn, MK; Song, MK; Shin, YI; Lee, YS; Joo, MC; Lee, SY; Han, JH; Ahn, J; Oh, GJ; Kim, YH
    View PubMed
  • GUT LIVER 2023 10.5009/gnl220337 Pretransplant Functional Status Predicts Postoperative Morbidity and Mortality after Liver Transplantation in Patients with Cirrhosis Goh, MJ; Kim, J; Chang, WH; Sinn, DH; Gwak, GY; Paik, YH; Choi, MS; Lee, JH; Koh, KC; Paik, SW; Kim, JM; Kang, WS
    View PubMed
  • FRONT AGING NEUROSCI 2023 10.3389/fnagi.2022.1059563 Relationship between lower limb muscle activity and cortical activation among elderly people during walking: Effects of fast speed and cognitive dual task Kim, J; Lee, JS; Lee, GHY; Chang, WH; Ko, MH; Yoo, WK; Ryu, GH; Kim, YH
    View PubMed
  • INT J ENV RES PUB HE 2023 10.3390/ijerph20010842 Increased Risk of Developing Depression in Disability after Stroke: A Korean Nationwide Study Choi, HL; Yang, KYJ; Han, KYD; Kim, B; Chang, WH; Kwon, S; Jung, WY; Yoo, JE; Jeon, HJ; Shin, DW
    View PubMed
  • J PERS MED 2023 10.3390/jpm13010131 Factors Associated with Unplanned Transfer of Patients with Brain Tumor from Inpatient Rehabilitation Unit to Primary Acute Care Units Nam, GH; Chang, WH
    View PubMed
  • J CLIN MED 2022 10.3390/jcm11247343 A Smart Glove Digital System Promotes Restoration of Upper Limb Motor Function and Enhances Cortical Hemodynamic Changes in Subacute Stroke Patients with Mild to Moderate Weakness: A Randomized Controlled Trial Shin, S; Lee, HJ; Chang, WH; Ko, SH; Shin, YI; Kim, YH
    View PubMed
  • STROKE 2022 10.1161/STROKEAHA.121.038196 Understanding of the Lower Extremity Motor Recovery After First-Ever Ischemic Stroke Lee, HH; Sohn, MK; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Lee, YH; Chang, WH; Choi, SM; Lee, SK; Lee, J; Kim, YH
    View PubMed
  • JAMA NETW OPEN 2022 10.1001/jamanetworkopen.2022.33094 Multifaceted Assessment of Functional Outcomes in Survivors of First-time Stroke Shin, S; Lee, Y; Chang, WH; Sohn, MK; Lee, J; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Kim, YH
    View PubMed
  • J PERS MED 2022 10.3390/jpm12091505 Clinical Characteristics and Risk Factors of First-Ever Stroke in Young Adults: A Multicenter, Prospective Cohort Study Jo, YJ; Kim, DH; Sohn, MK; Lee, J; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Chang, WH; Kim, YH; Kim, DY
    View PubMed
  • INT J ENV RES PUB HE 2022 10.3390/ijerph19159612 Changes in Long-Term Functional Independence in Patients with Moderate and Severe Ischemic Stroke: Comparison of the Responsiveness of the Modified Barthel Index and the Functional Independence Measure Lee, EY; Sohn, MK; Lee, JM; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Lee, SY; Song, MK; Han, JH; Ahn, JH; Lee, YH; Chang, WH; Choi, SM; Lee, SK; Joo, MC; Kim, YH
    View PubMed
  • STROKE 2022 10.1161/STROKEAHA.121.036545 Circulating Extracellular Vesicles in Stroke Patients Treated With Mesenchymal Stem Cells: A Biomarker Analysis of a Randomized Trial Bang, OY; Kim, EH; Cho, YH; Oh, MJ; Chung, JW; Chang, WH; Kim, YH; Yang, SW; Chopp, M
    View PubMed
  • CEREBELLUM 2022 10.1007/s12311-022-01416-1 M1 and Cerebellar tDCS for MSA-C: a Double-Blind, Randomized, Sham-Controlled, Crossover Study Ahn, JH; Lee, D; Kim, M; Cho, JW; Chang, WH; Youn, J
    View PubMed
  • DISABIL REHABIL 2022 10.1080/09638288.2022.2074154 Effects of the home-based exercise program with an augmented reality system on balance in patients with stroke: a randomized controlled trial Lee, JI; Park, J; Koo, J; Son, M; Hwang, JH; Lee, JY; Chang, WH
    View PubMed
  • J PERS MED 2022 10.3390/jpm12050822 Personalized Approaches to Stroke: One Step Forward for Functional Recovery of Stroke Patients Chang, WH
    View PubMed
  • FRONT NEUROL 2022 10.3389/fneur.2022.804206 Multichannel Transcranial Direct Current Stimulation Combined With Treadmill Gait Training in Patients With Parkinson's Disease: A Pilot Study Na, Y; Kim, J; Lee, SH; Kim, J; Lee, J; Shin, SY; Chang, WH; Cho, JW; Kim, YH
    View PubMed
  • J PERS MED 2022 10.3390/jpm12030432 Whole Brain Hemodynamic Response Based on Synchrony Analysis of Brain Signals for Effective Application of HD-tDCS in Stroke Patients: An fNIRS Study Lee, G; Lee, J; Kim, J; Kim, H; Chang, WH; Kim, YH
    View PubMed
  • J PERS MED 2022 10.3390/jpm12030389 Post-Stroke Depression and Cognitive Aging: A Multicenter, Prospective Cohort Study Shin, M; Sohn, MK; Lee, J; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Lee, YH; Chang, WH; Shin, S; Choi, SM; Lee, SK; Kim, YH
    View PubMed
  • STROKE 2022 10.1161/STROKEAHA.121.034505 Efficacy of Intravenous Mesenchymal Stem Cells for Motor Recovery After Ischemic Stroke: A Neuroimaging Study Lee, J; Chang, WH; Chung, JW; Kim, SK; Lee, JS; Sohn, SI; Kim, YH; Bang, OY
    View PubMed
  • ARCH PHYS MED REHAB 2021 10.1016/j.apmr.2021.07.788 Status Of Dysphagia After Ischemic Stroke: A Korean Nationwide Study Ko, N; Lee, HH; Sohn, MK; Kim, DY; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Song, MK; Han, J; Ahn, J; Lee, YH; Chang, WH; Choi, SM; Lee, SK; Lee, J; Kim, YH
    View PubMed
  • NEUROREHAB NEURAL RE 2021 10.1177/15459683211070278 Multimodal Imaging Biomarker-Based Model Using Stratification Strategies for Predicting Upper Extremity Motor Recovery in Severe Stroke Patients Lee, J; Kim, H; Kim, J; Chang, WH; Kim, YH
    View PubMed
  • SCI REP-UK 2021 10.1038/s41598-021-01182-w A structured exercise to relieve musculoskeletal pain caused by face-down posture after retinal surgery: a randomized controlled trial Kim, AY; Hwang, S; Kang, SW; Shin, SY; Chang, WH; Kim, SJ; Noh, H
    View PubMed
  • INT J ENV RES PUB HE 2021 10.3390/ijerph182212072 Different Effects of Robot-Assisted Gait and Independent Over-Ground Gait on Foot Plantar Pressure in Incomplete Spinal Cord Injury: A Preliminary Study Bae, YH; Chang, WH; Fong, SSM
    View PubMed
  • J PERS MED 2021 10.3390/jpm11111162 Relationship between the Corticospinal and Corticocerebellar Tracts and Their Role in Upper Extremity Motor Recovery in Stroke Patients Lee, J; Chang, WH; Kim, YH
    View PubMed
  • J PERS MED 2021 10.3390/jpm11111137 Probable Factors Associated with Response to Mesenchymal Stem Cell Therapy in Stroke Patients: A Post Hoc Analysis of the STARTING-2 Trial Chang, WH; Lee, J; Chung, JW; Kim, YH; Bang, OY
    View PubMed
  • DISABIL REHABIL 2021 10.1080/09638288.2021.1994660 Reliability and validity of the Korean version of the Functional Status Score for the ICU after translation and cross-cultural adaptation Do, JG; Suh, GY; Won, YH; Chang, WH; Hiser, S; Needham, DM; Chung, CR
    View PubMed
  • STROKE 2021 10.1161/STROKEAHA.120.032409 Revisiting the Proportional Recovery Model in View of the Ceiling Effect of Fugl-Meyer Assessment Lee, HH; Kim, DY; Sohn, MK; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Lee, SY; Han, J; Ahn, J; Chang, WH; Kim, I; Choi, SM; Lee, J; Kim, YH
    View PubMed
  • BMC GERIATR 2021 10.1186/s12877-021-02401-9 Correlation between cardiopulmonary metabolic energy cost and lower-limb muscle activity during inclined treadmill gait in older adults Kim, J; Lee, HJ; Lee, SH; Lee, J; Chang, WH; Ryu, GH; Kim, YH
    View PubMed
  • J PERS MED 2021 10.3390/jpm11060545 Cerebrolysin Combined with Rehabilitation Enhances Motor Recovery and Prevents Neural Network Degeneration in Ischemic Stroke Patients with Severe Motor Deficits Chang1, WH; Lee, J; Shin, YI; Ko, MH; Kim, DY; Sohn, MK; Kim, J; Kim, YH
    View PubMed
  • NEUROLOGY 2021 10.1212/WNL.0000000000011440 Efficacy and Safety of Intravenous Mesenchymal Stem Cells for Ischemic Stroke Chung1, JW; Chang, WH; Bang, OY; Moon, GJ; Kim, SJ; Kim, SK; Lee, JS; Sohn, SI; Kim, YH
    View PubMed
  • PLOS ONE 2021 10.1371/journal.pone.0246817 Brain morphological and connectivity changes on MRI after stem cell therapy in a rat stroke model Son1, JP; Sung, JH; Kim, DH; Cho, YH; Kim, SJ; Chung, JW; Chang, WH; Kim, YH; Kim, EH; Moon, GJ; Bang, OY
    View PubMed
  • NEUROSCI LETT 2021 10.1016/j.neulet.2020.135424 Optimal stimulation site for rTMS to improve motor function: Anatomical hand knob vs. hand motor hotspot Kim1, H; Kim, J; Lee, HJ; Lee, J; Na, Y; Chang, WH; Kim, YH
    View PubMed
  • J NEUROENG REHABIL 2020 10.1186/s12984-020-00777-0 Wearable hip-assist robot modulates cortical activation during gait in stroke patients a functional near-infrared spectroscopy study Lee1, SH; Lee, HJ; Shim, Y; Chang, WH; Choi, BO; Ryu, GH; Kim, YH
    View PubMed
  • NEURAL PLAST 2020 10.1155/2020/5742421 Differential Relationship between Microstructural Integrity in White Matter Tracts and Motor Recovery following Stroke Based on Brain-Derived Neurotrophic Factor Genotype Park1, E; Lee, J; Chang, WH; Lee, A; Hummel, FC; Kim, YH
    View PubMed
  • EUR J NEUROL 2020 10.1111/ene.14494 Differential early predictive factors for upper and lower extremity motor recovery after ischaemic stroke Lee1, J; Kim, H; Kim, J; Lee, HJ; Chang, WH; Kim, YH
    View PubMed
  • THER ADV NEUROL DISO 2020 10.1177/1756286420925679 Prediction of motor recovery using indirect connectivity in a lesion network after ischemic stroke Lee1, J; Park, E; Lee, A; Chang, WH; Kim, DS; Kim, YH
    View PubMed
  • STROKE 2020 10.1161/STROKEAHA.119.026829 Effect of Cognitive Reserve on Risk of Cognitive Impairment and Recovery After Stroke The KOSCO Study Shin1, M; Sohn, MK; Lee, J; Kim, DY; Lee, SG; Shin, YI; Oh, GJ; Lee, YS; Joo, MC; Han, EY; Han, J; Ahn, J; Chang, WH; Shin, MA; Choi, JY; Kang, SH; Kim, Y; Kim, YH
    View PubMed
  • TOP STROKE REHABIL 2020 10.1080/10749357.2019.1711338 Development and validation of a prediction model for home discharge in patients with moderate stroke: The Korean stroke cohort for functioning and rehabilitation study Kim1, MS; Joo, MC; Sohn, MK; Lee, J; Kim, DY; Lee, SG; Shin, YI; Kim, SY; Oh, GJ; Lee, YS; Han, EY; Han, J; Ahn, J; Chang, WH; Kim, YH; Choi, JY; Kang, SH; Kim, YT
    View PubMed
  • PLoS One 2020 10.1371/journal.pone.0226324 Determining the cut-off score for the Modified Barthel Index and the Modified Rankin Scale for assessment of functional independence and residual disability after stroke Lee1, SY; Kim, DY; Sohn, MK; Lee, J; Lee, SG; Shin, YI; Kim, SY; Oh, GJ; Lee, YH; Lee, YS; Joo, MC; Lee, SY; Ahn, J; Chang, WH; Choi, JY; Kang, SH; Kim, I; Han, J; Kim, YH
    View PubMed
  • STROKE 2019 10.1161/STROKEAHA.119.025950 Training for Walking Efficiency With a Wearable Hip-Assist Robot in Patients With Stroke: A Pilot Randomized Controlled Trial Lee1, HJ; Lee, SH; Seo, K; Lee, M; Chang, WH; Choi, BO; Ryu, GH; Kim, YH
    View PubMed
  • PAIN PHYSICIAN 2019 Hydraulic Distension with Pumping Technique for Treating Frozen Shoulder: A Case-Controlled, Retrospective, Comparative Study with 6-Month Follow-Up Kim1, YW; Shin, S; Chang, WH; Lee, SC
    View PubMed
  • BMJ OPEN 2019 10.1136/bmjopen-2018-028673 Factors influencing return to work after stroke: the Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) Study Han1, J; Lee, HI; Shin, YI; Son, JH; Kim, SY; Kim, DY; Sohn, MK; Lee, J; Lee, SG; Oh, GJ; Lee, YS; Joo, MC; Han, EY; Chang, WH; Kim, YH
    View PubMed
  • INT J GERONTOL 2019 10.6890/IJGE.201906_13(2).0008 Gender Differences in the Biomechanical and Physiological Properties of Gait in the Older Adults Lee1, HJ; Choi, DS; Lee, SY; Chang, WH; Kim, Y; Kim, YH
    View PubMed
  • Neural Plast 2019 10.1155/2019/3826495 Different Brain Connectivity between Responders and Nonresponders to Dual-Mode Noninvasive Brain Stimulation over Bilateral Primary Motor Cortices in Stroke Patients Lee1, J; Lee, A; Kim, H; Shin, M; Yun, SM; Jung, Y; Chang, WH; Kim, YH
    View PubMed
  • J CLIN NEUROL 2019 10.3988/jcn.2019.15.1.54 Impact of Functional Status on Noncardioembolic Ischemic Stroke Recurrence Within 1 Year: The Korean Stroke Cohort for Functioning and Rehabilitation Study Kim1, MS; Joo, MC; Sohn, MK; Lee, J; Kim, DY; Lee, SG; Shin, YI; Kim, SY; Oh, GJ; Lee, YS; Han, EY; Han, J; Ahn, J; Chang, WH; Kim, YH
    View PubMed
  • HUM BRAIN MAPP 2018 10.1002/hbm.24338 Differences in motor network dynamics during recovery between supra- and infra-tentorial ischemic strokes Lee1, J; Lee, A; Kim, H; Chang, WH; Kim, YH
    View PubMed
  • INT J MOL SCI 2018 10.3390/ijms19103131 Relationship between Serum BDNF Levels and Depressive Mood in Subacute Stroke Patients: A Preliminary Study Chang1, WH; Shin, MA; Lee, A; Kim, H; Kim, YH
    View PubMed
  • BMC Geriatr 2018 10.1186/s12877-018-0921-1 A wearable hip-assist robot reduces the cardiopulmonary metabolic energy expenditure during stair ascent in elderly adults: a pilot cross-sectional study Kim1, DS; Lee, HJ; Lee, SH; Chang, WH; Jang, J; Choi, BO; Ryu, GH; Kim, YH
    View PubMed
  • AM J PHYS MED REHAB 2018 10.1097/PHM.0000000000000916 Association Between Spasticity and Functional Impairments During the First Year After Stroke in Korea: The KOSCO Study Shin1, YI; Kim, SY; Lee, HI; Kim, DY; Lee, J; Sohn, MK; Lee, SG; Oh, GJ; Lee, YS; Joo, MC; Han, EY; Han, J; Moon, MH; Chang, WH; Kim, Y; Kim, YH
    View PubMed
  • BRAIN TOPOGR 2018 10.1007/s10548-018-0644-9 Alteration and Role of Interhemispheric and Intrahemispheric Connectivity in Motor Network After Stroke Lee1, J; Park, E; Lee, A; Chang, WH; Kim, DS; Kim, YH
    View PubMed
  • J KOREAN NEUROSURG SOC 2018 10.3340/jkns.2017.0404.005 Korean Clinical Practice Guidelines for Aneurysmal Subarachnoid Hemorrhage Cho1, WS; Kim, JE; Park, SQ; Ko, JK; Kim, DW; Park, JC; Yeon, JY; Chung, SY; Chung, J; Joo, SP; Hwang, G; Kim, DY; Chang, WH; Choi, KS; Lee, SH; Sheen, SH; Kang, HS; Kim, BM; Bae, HJ; Oh, CW; Park, HS
    View PubMed
  • Neural Plast 2018 10.1155/2018/1458061 Modulating Brain Connectivity by Simultaneous Dual- Mode Stimulation over Bilateral Primary Motor Cortices in Subacute Stroke Patients Lee1, J; Park, E; Lee, A; Chang, WH; Kim, DS; Shin, YI; Kim, YH
    View PubMed
  • J SPORT REHABIL 2018 10.1123/jsr.2016-0083 Comparison of the Therapeutic Effects of a Sling Exercise and a Traditional Stabilizing Exercise for Clinical Lumbar Spinal Instability Kim1, YW; Kim, NY; Chang, WH; Lee, SC
    View PubMed
  • J NEUROENG REHABIL 2017 10.1186/s12984-017-0333-z Gait performance and foot pressure distribution during wearable robot-assisted gait in elderly adults Lee1, SH; Lee, HJ; Chang, WH; Choi, BO; Lee, J; Kim, J; Ryu, GH; Kim, YH
    View PubMed
  • Transl Stroke Res 2017 10.1007/s12975-017-0538-2 Stroke Induces Mesenchymal Stem Cell Migration to Infarcted Brain Areas Via CXCR4 and C-Met Signaling Bang1, OY; Moon, GJ; Kim, DH; Lee, JH; Kim, S; Son, JP; Cho, YH; Chang, WH; Kim, YH
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