삼성서울병원

Ko En

Gastroenterology Park, Joo Kyung M.D

Expertise
Pancreatic Cancer, Biliary Tract Cancer, Gallbladder Cancer, Pancreas Cystic Tumor, Pancreatitis, Gallbladder Polyp, Gallbladder Stone, ERCP, Endoscopic Ultrasound
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Treament Schedule 06 月
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Medical Education

2000.02. Medical Doctor, College of Medicine, Seoul National University
2005.02. Master of Science, Seoul National University
2014.08. Ph.D. in Medicine, Seoul National University

Post-Graduate Training

Fellowship   2005-2008 Department of Medicine, Seoul National Universtiy Hospital
Residency   2001-2005 Department of Medicine, Seoul National Universtiy Hospital
Internship   2000-2001 Seoul National Universtiy Hospital

Professional Appointments

2024.03-Present Professor, Internal Medicine, Sungkyunkwan University College of Medicine
2015.03-Present Faculty, Gastroenterology, Samsung Medical Center
2009-2015 Assistant Professor, Gastroenterology,Seoul National Univerity Hospital
2009-2011 Visiting Scholar, Massachusetts General Hospital Harvard Medical School

Professional Memberships

A member of the American Cancer Research Association
A member of the American Pancreatic Association
A member of the International Association of Pancreatology
A member of the Korean Association of Internal Medicine
A member of the Korean Society of Gastroenterology
A member of the Korean Society of Gastrointestinal Endoscopy
A member of the Korean Society of Pancreaticobiliary Diseases
A member of the Korean Society of Gastrointestinal Cancer

Selected Publications

  • CLIN MOL HEPATOL 2025 10.3350/cmh.2024.0629 Safety and efficacy of HK-660S in patients with primary sclerosing cholangitis: A randomized double-blind phase 2a trial Paik, WH; Park, JK; Chung, MJ; Huh, G; Park, CH; Lee, SH; Jeong, HS; Kim, HJ; Park, D
    View PubMed
  • ONCOL RES 2025 10.32604/or.2024.049054 Comprehensive molecular characterization to predict immunotherapy response in advanced biliary tract cancer: a phase II trial of pembrolizumab Kim, R; Park, JK; Kwon, M; An, M; Hong, JY; Park, JO; Lim, SH; Kim, ST
    View PubMed
  • HEPATOB PANCREAT DIS 2024 10.1016/j.hbpd.2024.02.001 Bleeding after endoscopic papillectomy and its risk factors: A single center experience of 196 cases Choi, JH; Kim, WC; Park, JK; Lee, JK; Lee, KT; Lee, KH
    View PubMed
  • J CACHEXIA SARCOPENI 2024 10.1002/jcsm.13643 Skeletal Muscle Index Changes on Locoregional Treatment Application After FOLFIRINOX and Survival in Pancreatic Cancer Min, JH; Yu, JI; Kim, SH; Kim, YK; Kim, K; Park, HC; Park, JO; Hong, JY; Lee, KT; Lee, KH; Lee, JK; Park, JK; Choi, JH; Heo, JS; Han, IW; Kim, H; Shin, SH; Yoon, SJ; Woo, SY
    View PubMed
  • GASTROINTEST ENDOSC 2024 Establishment of a patient-specific avatar organoid model derived from EUS-guided fine-needle biopsy for timely clinical application in pancreatic ductal adenocarcinoma (with video) Kim, H; Jang, J; Choi, JH; Song, JH; Lee, SH; Park, JP; Ryoo, SK; Lee, EM; Jeong, HO; Kim, S; Lee, SH; Lee, KH; Lee, KT; Kim, KM; Jang, KT; Lee, H; Lee, S; Lee, JK; Park, JK
    View PubMed
  • BMJ OPEN 2024 10.1136/bmjopen-2024-084052 Aggressive hydration with lactated Ringer's solution versus plasma solution for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (ALPS study): protocol for a multicentre, double-blind, randomised controlled trial Cho, IR; Choi, JH; Park, JK; Huh, G; Lee, SH; Paik, WH; Park, DH
    View PubMed
  • MOL CANCER 2024 10.1186/s12943-024-02003-0 Single-cell transcriptome analysis reveals subtype-specific clonal evolution and microenvironmental changes in liver metastasis of pancreatic adenocarcinoma and their clinical implications Park, JK; Jeong, HO; Kim, H; Choi, JH; Lee, EM; Kim, S; Jang, J; Choi, DWY; Lee, SH; Kim, KM; Jang, KT; Lee, KH; Lee, KT; Lee, MW; Lee, JK; Lee, SM
    View PubMed
  • CLIN TRANSL RAD ONCO 2024 10.1016/j.ctro.2024.100732 Impact and optimal timing of local therapy addition in borderline resectable or locally advanced pancreatic cancer after FOLFIRINOX chemotherapy Kim, K; Park, HC; Yu, JI; Park, JO; Hong, JY; Lee, KT; Lee, KH; Lee, JK; Park, JK; Heo, JS; Shin, SH; Min, JH; Kim, K; Han, IW
    View PubMed
  • FRONT IMMUNOL 2024 10.3389/fimmu.2024.1321813 The predictive value of PD-L1 expression in response to anti-PD-1/PD-L1 therapy for biliary tract cancer: a systematic review and meta-analysis Yoon, SB; Woo, SM; Chun, JW; Kim, DU; Kim, J; Park, JK; So, HS; Chung, MJ; Cho, IR; Heo, J
    View PubMed
  • THER ADV MED ONCOL 2024 10.1177/17588359231225045 Prolonged progression-free survival achieved by gemcitabine, cisplatin, and albumin-bound paclitaxel for the treatment of advanced biliary tract cancers Choi, JH; Park, H; Park, JK; Lee, JK; Lee, KT; Lee, KH
    View PubMed
  • GUT LIVER 2023 10.5009/gnl230164 Outcomes of Palliative Chemotherapy for Ampulla of Vater Adenocarcinoma: A Multicenter Cohort Study Jang, DK; Kim, SJ; Chung, HH; Lee, JM; Yoon, SB; Lee, JC; Shin, DW; Hwang, JH; Jung, MK; Lee, YS; Lee, HS; Park, JK
    View PubMed
  • J TRANSL MED 2023 10.1186/s12967-023-04549-x Genetic assessment of pathogenic germline alterations in lysosomal genes among Asian patients with pancreatic ductal adenocarcinoma Koh, Y; Kim, H; Joo, SY; Song, SL; Choi, YH; Kim, HR; Moon, B; Byun, J; Hong, JS; Shin, DY; Park, S; Lee, KH; Lee, KT; Lee, JK; Park, D; Lee, SH; Jang, JY; Lee, H; Kim, JA; Yoon, SS; Park, JK
    View PubMed
  • J AM COLL SURGEONS 2023 10.1097/XCS.0000000000000769 Adjuvant Chemotherapy and Effect on Long-Term Survival in Ampullary Adenocarcinoma: A Multicenter Cohort Study Shin, DW; Lee, JM; Lee, JC; Lee, HS; Yoon, SB; Jang, DK; Park, JK; Jung, MK; Lee, YS; Hwang, JH
    View PubMed
  • SCI REP-UK 2023 10.1038/s41598-023-33867-9 Feasibility of in vivo swine models using guide wire-assisted intraductal radiofrequency ablation for benign biliary stricture Park, JK; Yang, JI; Park, JK; Lee, KH; Lee, JK; Lee, KT
    View PubMed
  • GUT LIVER 2023 10.5009/gnl220413 Diagnosis and Treatment of Perihilar Cholangiocarcinoma: A National Survey from the Korean Pancreatobiliary Association Cho, E; Kim, SH; Choi, SJ; Jung, MK; Song, BJ; Park, JM; Kang, JG; Park, WS; Park, JK; Woo, SM; Kim, HJ; Study Grp Biliary Dis; Korean Pancreatobiliary Assoc
    View PubMed
  • J PERS MED 2023 10.3390/jpm13010149 Comparison of Clinical and Imaginal Features According to the Pathological Grades of Dysplasia in Branch-Duct Intraductal Papillary Mucinous Neoplasm (BD-IPMN) for Personalized Medicine Na, JE; Park, JK; Lee, JK; Park, JK; Lee, KH; Lee, KT
    View PubMed
  • CANCER MED-US 2023 10.1002/cam4.5530 Comprehensive immunoprofile analysis of prognostic markers in pancreaticobiliary tract cancers Kim, JE; Kim, H; Kim, B; Chung, HG; Chung, HH; Kim, KM; Kim, SH; Jeong, WK; Kim, YK; Min, JH; Heo, JS; Han, IW; Shin, SH; Park, HC; Yu, JI; Park, JO; Kim, ST; Hong, JY; Lee, SH; Lee, KH; Lee, JK; Lee, KT; Jang, KT; Park, JK
    View PubMed
  • SURG ENDOSC 2022 10.1007/s00464-022-09856-w Long-term outcomes of endoscopic papillectomy for ampullary adenoma with high-grade dysplasia or adenocarcinoma: a propensity score-matched analysis Yoon, SB; Jung, MK; Lee, YS; Park, JK; Jang, DK; Lee, JM; Lee, HS; Shin, DW; Lee, JC; Hwang, JH
    View PubMed
  • GUT LIVER 2022 10.5009/gnl220044 Postoperative Prognostic Predictors of Bile Duct Cancers: Clinical Analysis and Immunoassays of Tissue Microarrays Chung, HH; Seo, SH; Kim, H; Kim, Y; Kim, DW; Lee, KH; Lee, KT; Heo, JS; Han, IW; Park, SM; Jang, KT; Lee, JK; Park, JK
    View PubMed
  • CANCERS 2022 10.3390/cancers14194556 The Feasibility of Stereotactic Body Proton Beam Therapy for Pancreatic Cancer Shin, H; Yu, JI; Park, HC; Yoo, GS; Cho, S; Park, JO; Lee, KT; Lee, KH; Lee, JK; Park, JK; Heo, JS; Han, IW; Shin, SH
    View PubMed
  • SCI REP-UK 2022 10.1038/s41598-022-14856-w Increased risk of pancreatic cancer in individuals with non-alcoholic fatty liver disease Park, JH; Hong, JY; Han, K; Kang, W; Park, JK
    View PubMed
  • J PERS MED 2022 10.3390/jpm12060855 Clinical Utility of Personalized Serum IgG Subclass Ratios for the Differentiation of IgG4-Related Sclerosing Cholangitis (IgG4-SC) from Primary Sclerosing Cholangitis (PSC) and Cholangiocarcinoma (CCA) Park, JK; Kim, D; Lee, JM; Lee, KH; Lee, KT; Park, JK; Lee, JK
    View PubMed
  • TRANSL ONCOL 2022 10.1016/j.tranon.2021.101321 Clinical significance of circulating tumor cells after chemotherapy in unresectable pancreatic ductal adenocarcinoma Kim, H; Heo, CM; Oh, J; Chung, HH; Lee, EM; Park, J; Lee, SH; Lee, KH; Lee, KT; Lee, JK; Cho, YK; Park, JK
    View PubMed
  • GUT LIVER 2021 10.5009/gnl210231 Diagnostic Concordance and Preoperative Risk Factors for Malignancy in Pancreatic Mucinous Cystic Neoplasms Kim, GH; Choi, K; Paik, N; Lee, KT; Lee, JK; Lee, KH; Han, IW; Kang, SH; Heo, JS; Park, JK
    View PubMed
  • PLOS ONE 2021 10.1371/journal.pone.0258887 Comparison of EUS and ERCP-guided tissue sampling in suspected biliary stricture Chung, HG; Chang, JI; Lee, KH; Park, JK; Lee, KT; Lee, JK
    View PubMed
  • FRONT MED-LAUSANNE 2021 10.3389/fmed.2021.719768 Risk Factors for High-Risk Adenoma on the First Lifetime Colonoscopy Using Decision Tree Method: A Cross-Sectional Study in 6,047 Asymptomatic Koreans Chung, KH; Park, MJ; Jin, EH; Seo, JY; Song, JH; Yang, SY; Kim, YS; Yim, JY; Lim, SH; Kim, JS; Chung, SJ; Park, JK
    View PubMed
  • CANCERS 2021 10.3390/cancers13112791 Accurate Prognosis Prediction of Pancreatic Ductal Adenocarcinoma Using Integrated Clinico-Genomic Data of Endoscopic Ultrasound-Guided Fine Needle Biopsy Park1, JK; Kim, H; Son, DS; Kim, NKD; Sung, YK; Cho, M; Lee, C; Noh, DH; Lee, SH; Lee, KT; Lee, JK; Jang, KT; Park, WY; Lee, KH
    View PubMed
  • J HEPATO-BIL-PAN SCI 2021 10.1002/jhbp.986 Multi-biomarker panel prediction model for diagnosis of pancreatic cancer Lee1, DH; Yoon, W; Lee, A; Han, Y; Byun, Y; Kang, JS; Kim, H; Kwon, W; Suh, YA; Choi, Y; Namkung, J; Han, S; Yi, SG; Heo, JS; Han, IW; Park, JO; Park, JK; Kim, SC; Jun, E; Kang, CM; Lee, WJ; Lee, HK; Lee, H; Lee, S; Jeong, SY; Lee, KE; Han, W; Park, T; Jang, JY
    View PubMed
  • EUR J CANCER 2021 10.1016/j.ejca.2021.03.024 Association between non-alcoholic fatty liver disease and the risk of biliary tract cancers: A South Korean nationwide cohort study Park1, JH; Hong, JY; Kwon, M; Lee, J; Han, K; Han, IW; Kang, W; Park, JK
    View PubMed
  • FRONT MED 2021 10.3389/fmed.2021.675207 Clinical Characteristics of Clonorchis sinensis-Associated Cholangiocarcinoma: A Large-Scale, Single-Center Study Chang1, JI; Lee, K; Kim, D; Yang, JI; Park, JK; Choi, K; Kang, SH; Lee, KH; Lee, KT; Lee, JK; Park, SM; Park, JK
    View PubMed
  • ANN SURG TREAT RES 2021 10.4174/astr.2021.100.3.144 Diagnostic model for pancreatic cancer using a multi-biomarker panel Choi1, YJ; Yoon, W; Lee, A; Han, Y; Byun, Y; Kang, JS; Kim, H; Kwon, W; Suh, YA; Kim, Y; Lee, S; Namkung, J; Han, S; Choi, Y; Heo, JS; Park, JO; Park, JK; Kim, SC; Kang, CM; Lee, WJ; Park, T; Jang, JY
    View PubMed
  • FRONT ONCOL 2021 10.3389/fonc.2020.616440 Detection of Circulating Tumor Cells in Resectable Pancreatic Ductal Adenocarcinoma: A Prospective Evaluation as a Prognostic Marker Song1, BG; Kwon, W; Kim, H; Lee, EM; Han, YM; Kim, H; Byun, Y; Lee, KB; Lee, KH; Lee, KT; Lee, JK; Jang, JY; Park, JK
    View PubMed
  • GUT LIVER 2020 10.5009/gnl19011 Factors of Endoscopic Ultrasound-Guided Tissue Acquisition for Successful Next-Generation Sequencing in Pancreatic Ductal Adenocarcinoma Park1, JK; Lee, JH; Noh, DH; Park, JK; Lee, KT; Lee, JK; Lee, KH; Jang, KT; Cho, J
    View PubMed
  • PANCREAS 2020 10.1097/MPA.0000000000001459 Primary and Metastatic Pancreatic Cancer Cells Exhibit Differential Migratory Potentials Park1, JK; Hank, T; Scherber, CM; Lillemoe, KD; Fernandez-del Castillo, C; Warshaw, AL; Toner, M; Irimia, D; Thayer, SP; Liss, AS
    View PubMed
  • GUT LIVER 2020 10.5009/gnl18387 Long-term Outcome of Endoscopic Retrograde Biliary Drainage of Biliary Stricture Following Living Donor Liver Transplantation Park1, JK; Yang, JI; Lee, JK; Park, JK; Lee, KH; Lee, KT; Joh, JW; Kwon, CHD; Kim, JM
    View PubMed
  • ALIMENT PHARM THER 2019 10.1111/apt.15466 Use of proton pump inhibitors and risk of cholangitis: a nationwide cohort study Min1, YW; Kang, D; Shin, JY; Kang, M; Park, LK; Lee, KH; Lee, JK; Lee, KT; Rhee, PL; Kim, JJ; Guallar, E; Cho, J; Lee, H
    View PubMed
  • SCAND J GASTROENTERO 2019 10.1080/00365521.2019.1619827 Prognosis and prognostic factors in patients with advanced biliary tract cancer depending on its anatomical location Song1, BG; Park, JK; Kim, HS; Kim, K; Park, JK; Lee, KH; Lee, KT; Lee, JK
    View PubMed
  • J GASTROEN HEPATOL 2019 10.1111/jgh.14611 Long-term outcome and recurrence factors after percutaneous cholecystostomy as a definitive treatment for acute cholecystitis Park1, JK; Yang, JI; Wi, JW; Park, JK; Lee, KH; Lee, KT; Lee, JK
    View PubMed
  • GASTROINTEST ENDOSC 2018 10.1016/j.gie.2018.06.024 Preoperative EUS-guided FNA: effects on peritoneal recurrence and survival in patients with pancreatic cancer Kim1, SH; Woo, YS; Lee, KH; Lee, JK; Lee, KT; Park, JK; Kang, SH; Kim, JW; Park, JK; Park, SW
    View PubMed
  • SCAND J GASTROENTERO 2018 10.1080/00365521.2018.1524021 Long term outcome of EUS-based strategy for suspected choledocholithiasis but negative CT finding Park1, JK; Lee, JK; Yang, JI; Lee, K; Park, JK; Lee, KH; Lee, KT
    View PubMed
  • CLIMACTERIC 2018 10.1080/13697137.2018.1481380 Association between nonalcoholic fatty liver disease and bone mineral density in postmenopausal women Lee1, DY; Park, JK; Hur, KY; Um, SH
    View PubMed
  • SCI REP-UK 2018 10.1038/s41598-018-30100-w Utility of targeted deep sequencing for detecting circulating tumor DNA in pancreatic cancer patients Park1, G; Park, JK; Son, DS; Shin, SH; Kim, YJ; Jeon, HJ; Lee, J; Park, WY; Lee, KH; Park, D
    View PubMed
  • GASTROINTEST ENDOSC 2018 10.1016/j.gie.2018.03.015 Efficacy of EUS-guided and ERCP-guided biliary drainage for malignant biliary obstruction: prospective randomized controlled study Park1, JK; Woo, YS; Noh, DH; Yang, JI; Bae, SY; Yun, HS; Lee, JK; Lee, KT; Lee, KH
    View PubMed
  • J CLIN GASTROENTEROL 2018 10.1097/MCG.0000000000000900 Predictive Model for Neoplastic Potential of Gallbladder Polyp Yang1, JI; Lee, JK; Ahn, DG; Park, JK; Lee, KH; Lee, KT; Chi, SA; Jung, SH
    View PubMed
  • SCAND J GASTROENTERO 2017 10.1080/00365521.2017.1322136 22G versus 25G biopsy needles for EUS-guided tissue sampling of solid pancreatic masses: a randomized controlled study Woo1, YS; Lee, KH; Noh, DH; Park, JK; Lee, KT; Lee, JK; Jang, KT
    View PubMed
  • ONCOTARGET 2017 10.18632/oncotarget.16135 Additional K-ras mutation analysis and Plectin-1 staining improve the diagnostic accuracy of pancreatic solid mass in EUS-guided fine needle aspiration Park1, JK; Paik, WH; Song, BJ; Ryu, JK; Kim, MA; Park, JM; Lee, SH; Kim, YT
    View PubMed
  • GENOME BIOL 2017 10.1186/s13059-017-1275-2 Characterization of background noise in capture-based targeted sequencing data Park1, G; Park, JK; Shin, SH; Jeon, HJ; Kim, NKD; Kim, YJ; Shin, HT; Lee, E; Lee, KH; Son, DS; Park, WY; Park, D
    View PubMed
  • ONCOTARGET 2017 10.18632/oncotarget.17964 DAXX/ATRX and MEN1 genes are strong prognostic markers in pancreatic neuroendocrine tumors Park1, JK; Paik, WH; Lee, K; Ryu, JK; Lee, SH; Kim, YT
    View PubMed
  • Oncotarget. 2017 Jan 10;8(2):3519-3527. doi: 10.18632/oncotarget.13864. KRAS mutation analysis of washing fluid from endoscopic ultrasound-guided fine needle aspiration improves cytologic diagnosis of pancreatic ductal adenocarcinoma Park JK11, Lee YJ1, Lee JK1, Lee KT1, Choi YL2, Lee KH1,3.
    View PubMed
  • Medicine (Baltimore). 2016 Dec;95(51):e5535. doi: 10.1097/MD.0000000000005535. Incidental pancreatic cystic neoplasms in an asymptomatic healthy population of 21,745 individuals Large-scale, single-center cohort study Chang YR11, Park JK, Jang JY, Kwon W, Yoon JH, Kim SW.
    View PubMed
  • Oncotarget. 2016 Nov 15;7(46):75081-75093. doi: 10.18632/oncotarget.12057. The anti-fibrotic effect of GV1001 combined with gemcitabine on treatment of pancreatic ductal adenocarcinoma Park JK11, Kim Y2, Kim H2,3, Jeon J2, Kim TW4, Park JH5, Hwnag YI2, Lee WJ2, Kang JS2,3.
    View PubMed
  • Surg Endosc. 2016 Sep;30(9):3897-903. doi: 10.1007/s00464-015-4695-7. Epub 2015 Dec 18. SpyGlass cholangioscopy-assisted guidewire placement for post-LDLT biliary strictures: a case series Woo YS11, Lee JK2, Noh DH3, Park JK3, Lee KH3, Lee KT3.
    View PubMed
  • Pancreas. 2016 Jul;45(6):889-94. doi: 10.1097/MPA.0000000000000567. Clinical Outcomes of Endoscopic Ultrasonography-Guided Pancreatic Cyst Ablation Park JK11, Song BJ, Ryu JK, Paik WH, Park JM, Kim J, Lee SH, Kim YT.
    View PubMed
  • Medicine (Baltimore). 2016 May;95(21):e3740. doi: 10.1097/MD.0000000000003740. Evaluating the Minimal Specimens From Endoscopic Ultrasound-Guided Fine-Needle Aspiration in Pancreatic Masses Park JK11, Kang KJ, Oh CR, Lee JK, Lee KT, Jang KT, Park SM, Lee KH.
    View PubMed
  • Surg Endosc. 2016 Mar;30(3):1141-5. doi: 10.1007/s00464-015-4317-4. Epub 2015 Jun 27. Novel flower-type covered metal stent to prevent cholecystitis: experimental study in a pig model Woo YS11, Lee KH2, Lee JK3, Noh DH2, Park JK2, Lee KT2, Jang KT4.
    View PubMed
  • World J Gastroenterol. 2015 Jun 28;21(24):7506-13. doi: 10.3748/wjg.v21.i24.7506. Risk factors of organ failure in cholangitis with bacteriobilia Lee JM11, Lee SH1, Chung KH1, Park JM1, Lee BS1, Paik WH1, Park JK1, Ryu JK1, Kim YT1.
    View PubMed