Introduction of MR-Guided Focused Ultrasound (MRgFUS) Surgery Equipment

2021.08.10  87

Neurology Department at Samsung Medical Center is scheduled to introduce a Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) equipment in September.

 

The principle of brain surgery using an ultrasound is to cover the head with 1,024 ultrasound generators and raising the temperature of the brain tissue, thereby inducing necrosis and destroying the target area by focusing ultrasound waves based on the magnetic resonance imaging.

 

The surgery is performed without any anesthesia or incisions. During the surgery, the temperature deep in the brain is measured by magnetic resonance imaging in real-time, and the improvement of the symptoms is checked simultaneously. Parkinson's disease, whose main symptoms are essential tremor and hand tremor that do not respond to drugs, is the disease with the safest and is most clearly proven to have a therapeutic effect to date.

 

Existing treatment methods for those diseases include direct insertion of electrodes and applying heat by passing high-frequency waves, deep brain stimulation in which electrodes are permanently implanted in the deep brain to apply electrical stimulation, and gamma knife to target radiation. There are also methods such as radio-surgery that focus on the target area. Each method has advantages and disadvantages depending on the patient's condition. The major advantage of ultrasound surgery is that it does not use invasive methods such as anesthesia or incision to directly insert electrodes into the brain, and it can monitor the treatment response during surgery in real-time to minimize complications and increase treatment effect.

 

Furthermore, the therapeutic effect appears immediately, and there is no delay in radiation-induced complications or the hassle of managing a permanently implanted device for deep brain stimulation.

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