The NCI Patient Reported Outcomes-Common Terminology Criteria for Adverse Events (PRO-CTCAE) is a new patient-reported outcome measurement system developed to characterize the frequency, severity and interference of 78 symptomatic treatment toxicities. These include symptomatic toxicities such as pain, fatigue, nausea, and cutaneous side effects such as rash and hand-foot syndrome, all toxicities that can be meaningfully reported from the patient perspective.
The PRO-CTCAE measurement system includes an item library of 124 discrete items representing 78 symptomatic toxicities drawn from the CTCAE. As such, it provides a systematic yet flexible approach to capture symptomatic adverse events in trials of new cancer therapies.
Validation paper
- Cho J, Yoon J, Kim Y, Oh D, Kim SJ, Ahn J, Suh GY, Nam SJ, Mitchell SA. Linguistic Validation of the US National Cancer Institute's Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events in Korean. J Glob Oncol 2019 Mar;5:1-10. doi: 10.1200/JGO.18.00193.
Download
- https://healthcaredelivery.cancer.gov/pro-ctcae/instrument.html
Contact
- Juhee Cho: jcho@skku.edu