WORLD NEUROSURG 2021 10.1016/j.wneu.2021.03.085

Safety and Efficacy of Endoscopic Dorsum Sellar Resection for Access to Retroinfundibular or Upper Clival Tumors (Korean Society of Endoscopic Neurosurgery-008)

Kong¹, DS; Hong, SD; Kang, H; Seo, Y; Kim, MS; Seol, HJ; Park, CK; Nam, DH; Lee, JI; Kim, YH

INT J MOL SCI 2021 10.3390/ijms22126240

Semi-Automated Cell Panning for Efficient Isolation of FGFR3-Targeting Antibody

Min¹, B; Yoo, M; Kim, H; Cho, M; Nam, DH; Yoon, Y

EUR ARCH OTO-RHINO-L 2021 10.1007/s00405-021-06877-4

Learning curve and technical nuances of endoscopic skull base reconstruction with nasoseptal flap to control high-flow cerebrospinal fluid leakage: reconstruction after endoscopic skull base surgery other than pituitary surgery

Park¹, W; Nam, D; Kong, DS; Lee, KE; Park, SI; Kim, HY; Chung, SK; Jung, YG; Hong, SD

J NEURO-ONCOL 2021 10.1007/s11060-021-03774-y

Early hormonal recovery following endoscopic transsphenoidal surgery for silent non-functioning pituitary adenomas with hormone dysfunction

Lee¹, MH; Hur, KY; Hong, SD; Seol, HJ; Choi, JW; Lee, JI; Nam, D; Kong, DS

CELL DEATH DIS 2021 10.1038/s41419-021-03657-0

Mutation-specific non-canonical pathway of PTEN as a distinct therapeutic target for glioblastoma

Choi¹, SW; Lee, Y; Shin, K; Koo, H; Kim, D; Sa, JK; Cho, HJ; Shin, HM; Lee, SJ; Kim, H; Chung, S; Shin, J; Lee, C; Nam, DH

J KOREAN MED SCI 2021 10.3346/jkms.2021.36.e102

Optimal Volume of the Residual Tumor to Predict Long-term Tumor Control Using Stereotactic Radiosurgery after Facial Nerve-preserving Surgery for Vestibular Schwannomas

Lee¹, WJ; Lee, JI; Choi, JW; Kong, DS; Nam, DH; Cho, YS; Shin, HJ; Seol, HJ

ISCIENCE 2021 10.1016/j.isci.2021.102238

Azathioprine antagonizes aberrantly elevated lipid metabolism and induces apoptosis in glioblastoma

Nam¹, HJ; Kim, YE; Moon, BS; Kim, HY; Jung, D; Choi, S; Jang, JW; Nam, DH; Cho, H

J KOREAN NEUROSURG SOC 2021 10.3340/jkns.2020.0135

Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer with Brain Metastasis : The Role of Gamma Knife Radiosurgery

Lee¹, MH; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Jung, HA; Sun, JM; Lee, SH; Ahn, JS; Ahn, MJ; Park, K; Lee, JI

CANCER LETT 2021 10.1016/j.canlet.2020.10.050

Clinical practice guidelines for the management of adult diffuse gliomas

Jiang¹, T; Nam, DH; Ram, Z; Poon, WS; Wang, JG; Boldbaatar, D; Mao, Y; Ma, WB; Mao, Q; You, YP; Jiang, CL; Yang, XJ; Kang, CS; Qiu, XG; Li, WB; Li, SW; Chen, L; Li, XJ; Liu, ZX; Wang, WM; Bai, HM; Yao, Y; Li, SW; Wu, AH; Sai, K; Li, GL; Yao, K; Wei, XT; Liu, XZ; Zhang, ZW; Dai, YW; Lv, SQ; Wang, L; Lin, ZX; Dong, J; Xu, GZ; Ma, XD; Zhang, W; Zhang, CB; Chen, BS; You, G; Wang, YZ; Wang, YY; Bao, ZS; Yang, P; Fan, X; Liu, X; Zhao, Z; Wang, Z; Li, YM; Wang, ZL; Li, GZ; Fang, SY; Li, LW; Liu, YW; Liu, S; Shan, X; Liu, YQ; Chai, RC; Hu, HM; Chen, J; Yan, W; Cai, JQ; Wang, HJ; Chen, LC; Yang, Y; Wang, Y; Han, L; Wang, QX

BRAIN 2021 10.1093/brain/awaa433

Modulation of Nogo receptor 1 expression orchestrates myelin-associated infiltration of glioblastoma

Hong¹, JH; Kang, S; Sa, JK; Park, G; Oh, YT; Kim, TH; Yin, J; Kim, SS; D'Angelo, F; Koo, H; You, Y; Park, S; Kwon, HJ; Kim, CI; Ryu, H; Lin, W; Park, EJ; Kim, YJ; Park, MJ; Kim, H; Kim, MS; Chung, S; Park, CK; Park, SH; Kang, YH; Kim, JH; Saya, H; Nakano, I; Gwak, HS; Yoo, H; Lee, J; Hur, EM; Shi, BY; Nam, DH; Iavarone, A; Lee, SH; Park, JB

CANCERS 2021 10.3390/cancers13030372

High-Content Analysis-Based Sensitivity Prediction and Novel Therapeutics Screening for c-Met-Addicted Glioblastoma

Oh¹, JW; Oh, YJ; Han, S; Her, NG; Nam, DH

STEREOT FUNCT NEUROS 2020 10.1159/000508737

Gamma Knife Radiosurgery as a Primary Treatment for Nonfunctioning Pituitary Adenoma Invading the Cavernous Sinus

Lee¹, WJ; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI

CANCERS 2020 10.3390/cancers12113210

Therapeutic Efficacy of GC1118, a Novel Anti-EGFR Antibody, against Glioblastoma with High EGFR Amplification in Patient-Derived Xenografts

Lee¹, K; Koo, H; Kim, YJ; Kim, D; Son, E; Yang, H; Lim, Y; Hur, M; Lee, HW; Choi, SW; Nam, DH

ACS OMEGA 2020 10.1021/acsomega.0c03102

cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody-Drug Conjugate Targeting c-Met Overexpression Tumors

Min¹, B; Jin, J; Kim, H; Her, NG; Park, C; Kim, D; Yang, J; Hwang, J; Kim, E; Choi, M; Song, HY; Nam, DH; Yoon, Y

J NEUROSURG 2020 10.3171/2019.5.JNS19222

Outcome evaluation of patients treated with fractionated Gamma Knife radiosurgery for large (> 3 cm) brain metastases a dose-escalation study

Kim¹, KH; Kong, DS; Cho, KR; Lee, MH; Choi, JW; Seol, HJ; Kim, ST; Nam, DH; Lee, JI

ACTA NEUROCHIR 2020 10.1007/s00701-020-04575-4

Stereotactic radiosurgery for orbital cavernous venous malformation a single center's experience for 15 years

Lee¹, WJ; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, D; Kim, YD; Woo, KI; Lee, JI

NAT COMMUN 2020 10.1038/s41467-020-18189-y

Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy

Bastola¹, S; Pavlyukov, MS; Yamashita, D; Ghosh, S; Cho, H; Kagaya, N; Zhang, Z; Minata, M; Lee, Y; Sadahiro, H; Yamaguchi, S; Komarova, S; Yang, E; Markert, J; Nabors, LB; Bhat, K; Lee, J; Chen, Q; Crossman, DK; Shin-Ya, K; Nam, DH; Nakano, I

NAT COMMUN 2020 10.1038/s41467-020-17717-0

MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

Oldrini¹, B; Vaquero-Siguero, N; Mu, QH; Kroon, P; Zhang, Y; Galan-Ganga, M; Bao, ZS; Wang, Z; Liu, HJ; Sa, JK; Zhao, JF; Kim, H; Rodriguez-Perales, S; Nam, DH; Verhaak, RGW; Rabadan, R; Jiang, T; Wang, JG; Squatrito, M

CLIN EXP OTORHINOLARYNGOL 2020 10.21053/ceo.2019.01466

A Comparison of Olfactory and Sinonasal Outcomes in Endoscopic Pituitary Surgery Performed by a Single Neurosurgeon or a Collaborative Team of Surgeons

Noh¹, Y; Choi, JE; Lee, KE; Kong, DS; Nam, DH; Jung, YG; Kim, HY; Chung, SK; Hong, SD

GENOME BIOL 2020 10.1186/s13059-020-02140-x

Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

Sa¹, JK; Chang, N; Lee, HW; Cho, HJ; Ceccarelli, M; Cerulo, L; Yin, JL; Kim, SS; Caruso, FP; Lee, M; Kim, D; Oh, YT; Lee, Y; Her, NG; Min, B; Kim, HJ; Jeong, DE; Kim, HM; Kim, H; Chung, S; Woo, HG; Lee, J; Kong, DS; Seol, HJ; Lee, JI; Kim, J; Park, WY; Wang, QH; Sulman, EP; Heimberger, AB; Lim, M; Park, JB; Iavarone, A; Verhaak, RGW; Nam, DH

CANCER MED 2020 10.1002/cam4.3370

Ethnic delineation of primary glioblastoma genome

Koo¹, H; Choi, SW; Cho, HJ; Lee, IH; Kong, DS; Seol, HJ; Lee, JI; Choi, JW; Sa, JK; Nam, DH

CLIN NEUROL NEUROSUR 2020 10.1016/j.clineuro.2020.105847

Two-staged gamma knife radiosurgery for treatment of numerous (> 10) brain metastases

Kim¹, M; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI

NAT COMMUN 2020 10.1038/s41467-020-17139-y

Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities

Oh¹, S; Yeom, J; Cho, HJ; Kim, JH; Yoon, SJ; Kim, H; Sa, JK; Ju, S; Lee, H; Oh, MJ; Lee, W; Kwon, Y; Li, HL; Choi, S; Han, JH; Chang, JH; Choi, E; Kim, J; Her, NG; Kim, SH; Kang, SG; Paek, E; Nam, DH; Lee, C; Kim, HS

SCI REP-UK 2020 10.1038/s41598-020-67842-5

Molecular dissection of CRC primary tumors and their matched liver metastases reveals critical role of immune microenvironment, EMT and angiogenesis in cancer metastasis

Liu¹, JG; Cho, YB; Hong, HK; Wu, S; Ebert, PJ; Bray, SM; Wong, SS; Ting, JC; Calley, JN; Whittington, CF; Bhagwat, SV; Reinhard, C; Wild, R; Nam, DH; Aggarwal, A; Lee, WY; Peng, SB

CANCERS 2020 10.3390/cancers12071707

Multi-Habitat Radiomics Unravels Distinct Phenotypic Subtypes of Glioblastoma with Clinical and Genomic Significance

Choi¹, SW; Cho, HH; Koo, H; Cho, KR; Nenning, KH; Langs, G; Furtner, J; Baumann, B; Woehrer, A; Cho, HJ; Sa, JK; Kong, DS; Seol, HJ; Lee, JI; Nam, DH; Park, H

J NEUROSURG 2020 10.3171/2019.3.JNS183130

Volumetric changes of intracranial metastases during the course of fractionated stereotactic radiosurgery and significance of adaptive planning

Lee¹, MH; Kim, KH; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI

J CLIN NEUROSCI 2020 10.1016/j.jocn.2020.04.047

Pattern of disease progression following stereotactic radiosurgery in malignant glioma patients

Choi¹, SW; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI

J NEURO-ONCOL 2020 10.1007/s11060-020-03468-x

Chemoradiation in elderly patients with glioblastoma from the multi-institutional GBM-molRPA cohort: is short-course radiotherapy enough or is it a matter of selection?

Wee¹, CW; Kim, IH; Park, CK; Kim, N; Suh, CO; Chang, JH; Lim, HD; Nam, D; Kim, IA; Kim, CY; Oh, YT; Chung, WK; Kim, SH

WORLD NEUROSURG 2020 10.1016/j.wneu.2019.12.023

Morbidities Associated with the Endoscopic Transnasal Transpterygoid Approach: Focusing on Postoperative Sequelae

Choi¹, JE; Noh, YS; Lee, KE; Jung, YG; Chung, SK; Kim, HY; Kong, DS; Nam, DH; Hong, SD

Genome Med 2020 10.1186/s13073-020-00741-6

Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient

Lee¹, HW; Chung, W; Lee, HO; Jeong, D; Jo, A; Lim, JE; Hong, JH; Nam, DH; Jeong, BC; Park, SH; Joo, KM; Park, WY

CANCER RES TREAT 2020 10.4143/crt.2019.421

Concurrent and Adjuvant Temozolomide for Newly Diagnosed Grade III Gliomas without 1p/19q Co-deletion: A Randomized, Open-Label, Phase 2 Study (KNOG-1101 Study)

Hwang¹, K; Kim, TM; Park, CK; Chang, JH; Jung, TY; Kim, JH; Nam, DH; Kim, SH; Yoo, H; Hong, YK; Kim, EY; Lee, DE; Joo, J; Kim, YJ; Choe, G; Choi, BS; Kang, SG; Kim, JH; Kim, CY

Biomed Signal Process Control 2020 10.1016/j.bspc.2020.101846

Accuracy improvement of quantification information using super-resolution with convolutional neural network for microscopy images

Kang¹, MS; Cha, E; Kang, E; Ye, JC; Her, NG; Oh, JW; Nam, DH; Kim, MH; Yang, S

TARGET ONCOL 2020 10.1007/s11523-020-00706-0

Use of Gefitinib in EGFR-Amplified Refractory Solid Tumors: An Open-Label, Single-Arm, Single-Center Prospective Pilot Study

Byeon¹, S; Hong, JY; Lee, J; Nam, DH; Park, SH; Park, JO; Park, YS; Lim, HY; Kang, WK; Kim, ST

CANCERS 2020 10.3390/cancers12040866

Integrative Radiogenomics Approach for Risk Assessment of Post-Operative Metastasis in Pathological T1 Renal Cell Carcinoma: A Pilot Retrospective Cohort Study

Lee¹, HW; Cho, HH; Joung, JG; Jeon, HG; Jeong, BC; Jeon, SS; Lee, HM; Nam, DH; Park, WY; Kim, CK; Seo, SI; Park, H

CANCERS 2020 10.3390/cancers12030549

Sphere-Forming Culture for Expanding Genetically Distinct Patient-Derived Glioma Stem Cells by Cellular Growth Rate Screening

Shin¹, K; Shin, H; Cho, HJ; Kang, H; Lee, JK; Seo, YJ; Shin, YJ; Kim, D; Koo, H; Kong, DS; Seol, HJ; Lee, JI; Lee, HW; Nam, DH

J CLIN MED 2020 10.3390/jcm9020533

Plasma Lysyl-tRNA Synthetase 1 (KARS1) as a Novel Diagnostic and Monitoring Biomarker for Colorectal Cancer

Suh¹, JH; Park, MC; Goughnour, PC; Min, BS; Kim, SB; Lee, WY; Cho, YB; Cheon, JH; Lee, KY; Nam, DH; Kim, S

Genome Med 2020 10.1186/s13073-020-0717-8

Comprehensive pharmacogenomic characterization of gastric cancer

Sa¹, JK; Hong, JY; Lee, IK; Kim, JS; Sim, MH; Kim, HJ; An, JY; Sohn, TS; Lee, JH; Bae, JM; Kim, S; Kim, KM; Kim, ST; Park, SH; Park, JO; Lim, HY; Kang, WK; Her, NG; Lee, Y; Cho, HJ; Shin, YJ; Kim, M; Koo, H; Kim, M; Seo, YJ; Kim, JY; Choi, MG; Nam, DH; Lee, J

J NEURO-ONCOL 2020 10.1007/s11060-019-03361-2

Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial

Kim¹, CY; Paek, SH; Nam, D; Chang, JH; Hong, YK; Kim, JH; Kim, OL; Kim, SH

CANCER SCI 2020 10.1111/cas.14254

Phase 1 study of capmatinib in MET-positive solid tumor patients: Dose escalation and expansion of selected cohorts

Bang¹, YJ; Su, WC; Schuler, M; Nam, DH; Lim, WT; Bauer, TM; Azaro, A; Poon, RTP; Hong, D; Lin, CC; Akimov, M; Ghebremariam, S; Zhao, S; Giovannini, M; Ma, B

BMC OPHTHALMOL 2020 10.1186/s12886-019-1285-9

Markedly increased ocular side effect causing severe vision deterioration after chemotherapy using new or investigational epidermal or fibroblast growth factor receptor inhibitors

Shin¹, E; Lim, DH; Han, JS; Nam, D; Park, K; Ahn, MJ; Kang, WK; Lee, JY; Ahn, JS; Lee, SH; Sun, JM; Jung, HA; Chung, TY

CANCER RES TREAT 2020 10.4143/crt.2019.036

Clinical Targeted Next-Generation Sequencing Panels for Detection of Somatic Variants in Gliomas

Shin¹, H; Sa, JK; Bae, JS; Koo, H; Jin, S; Cho, HJ; Choi, SW; Kyoung, JM; Kim, JY; Seo, YJ; Joung, JG; Kim, NKD; Son, DS; Chung, J; Lee, T; Kong, DS; Choi, JW; Seol, HJ; Lee, JI; Suh, YL; Park, WY; Nam, DH

WORLD NEUROSURG 2019 10.1016/j.wneu.2019.08.067

Delayed Cerebrospinal Fluid Leakage After Treatment of Skull Base Tumors: Case Series of 9 Patients

Lee¹, JJ; Kim, HY; Dhong, HJ; Chung, SK; Kong, DS; Nam, DH; So, YK; Hong, SD

J NEURO-ONCOL 2019 10.1007/s11060-019-03328-3

Fractionated stereotactic radiosurgery for malignant gliomas: comparison with single session stereotactic radiosurgery

Choi¹, SW; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI

NATURE 2019 10.1038/s41586-019-1775-1

Longitudinal molecular trajectories of diffuse glioma in adults

Barthel¹, FP; Johnson, KC; Varn, FS; Moskalik, AD; Tanner, G; Kocakavuk, E; Anderson, KJ; Abiola, O; Aldape, K; Alfaro, KD; Alpar, D; Amin, SB; Ashley, DM; Bandopadhayay, P; Barnholtz-Sloan, JS; Beroukhim, R; Bock, C; Brastianos, PK; Brat, DJ; Brodbelt, AR; Bruns, AF; Bulsara, KR; Chakrabarty, A; Chakravarti, A; Chuang, JH; Claus, EB; Cochran, EJ; Connelly, J; Costello, JF; Finocchiaro, G; Fletcher, MN; French, PJ; Gan, HK; Gilbert, MR; Gould, PV; Grimmer, MR; Iavarone, A; Ismail, A; Jenkinson, MD; Khasraw, M; Kim, H; Kouwenhoven, MCM; LaViolette, PS; Li, MH; Lichter, P; Ligon, KL; Lowman, AK; Malta, TM; Mazor, T; McDonald, KL; Molinaro, AM; Nam, DH; Nayyar, N; Ng, HK; Ngan, CY; Niclou, SP; Niers, JM; Noushmehr, H; Noorbakhsh, J; Ormond, DR; Park, CK; Poisson, LM; Rabadan, R; Radlwimmer, B; Rao, G; Reifenberger, G; Sa, JK; Schuster, M; Shaw, BL; Short, SC; Smitt, PAS; Sloan, AE; Smits, M; Suzuki, H; Tabatabai, G; Van Meir, EG; Watts, C; Weller, M; Wesseling, P; Westerman, BA; Widhalm, G

INT J MOL SCI 2019 10.3390/ijms20235894

Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts

Lee¹, HW; Son, E; Lee, K; Lee, Y; Kim, Y; Lee, JC; Lim, Y; Hur, M; Kim, D; Nam, DH

EXP MOL MED 2019 10.1038/s12276-019-0351-y

Secretome analysis of patient-derived GBM tumor spheres identifies midkine as a potent therapeutic target

Han¹, S; Shin, H; Lee, JK; Liu, ZQ; Rabadan, R; Lee, J; Shin, J; Lee, C; Yang, H; Kim, D; Kim, SH; Kim, J; Oh, JW; Kong, DS; Lee, JI; Seol, HJ; Choi, JW; Kang, HJ; Nam, DH

WORLD NEUROSURG 2019 10.1016/j.wneu.2019.08.031

Clinical Efficacy of Optical Coherence Tomography to Predict the Visual Outcome After Endoscopic Endonasal Surgery for Suprasellar Tumors

Jeon¹, C; Park, KA; Hong, SD; Choi, JW; Seol, HJ; Nam, DH; Lee, JI; Shin, HJ; Kong, DS

WORLD NEUROSURG 2019 10.1016/j.wneu.2019.07.218

Clinical Significance of Tumor-Related Edema of Optic Tract Affecting Visual Function in Patients with Sellar and Suprasellar Tumors

Ju¹, DG; Jeon, C; Kim, KH; Park, KA; Hong, SD; Seoul, HJ; Shin, HJ; Nam, DH; Lee, JI; Kong, DS

NAT COMMUN 2019 10.1038/s41467-019-13082-9

Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy

Khattar¹, E; Maung, KZY; Chew, CL; Ghosh, A; Mok, MMH; Lee, P; Zhang, J; Chor, WHJ; Cildir, G; Wang, CQ; Mohd-Ismail, NK; Chin, DWL; Lee, SC; Yang, H; Shin, YJ; Nam, DH; Chen, LM; Kumar, AP; Deng, LW; Ikawa, M; Gunaratne, J; Osato, M; Tergaonkar, V

Front Oncol 2019 10.3389/fonc.2019.01327

Systematic Evaluation of Gastric Tumor Cell Index and Two-Drug Combination Therapy via 3-Dimensional High-Throughput Drug Screening

Lim¹, SH; Sa, JK; Lee, DW; Kim, J; Kim, ST; Park, SH; Ku, B; Park, JO; Park, YS; Lim, H; Kang, WK; Nam, DH; Lee, J

CANCER SCI 2019 10.1111/cas.14254

Phase 1 study of capmatinib in MET-positive solid tumor patients: Dose escalation and expansion of selected cohorts

Bang¹, YJ; Su, WC; Schuler, M; Nam, DH; Lim, WT; Bauer, TM; Azaro, A; Poon, RTP; Hong, D; Lin, CC; Akimov, M; Ghebremariam, S; Zhao, S; Giovannini, M; Ma, B

MICRON 2019 10.1016/j.micron.2019.102718

Automated stitching of microscope images of fluorescence in cells with minimal overlap

Seo¹, JH; Yang, S; Kang, MS; Her, NG; Nam, DH; Choi, JH; Kim, MH

NEUROSURG REV 2019 10.1007/s10143-019-01213-1

Comparison between retrosigmoid and translabyrinthine approaches for large vestibular schwannoma: focus on cerebellar injury and morbidities

Kim¹, KH; Cho, YS; Seol, HJ; Cho, KR; Choi, JW; Kong, DS; Shin, HJ; Nam, DH; Lee, JI

J MOL MED-JMM 2019 10.1007/s00109-019-01815-8

Molecular changes in solitary fibrous tumor progression

Park¹, HK; Yu, DB; Sung, MJ; Oh, E; Kim, M; Song, JY; Lee, MS; Jung, K; Noh, KW; An, S; Song, K; Nam, DH; Kim, YJ; Choi, YL

CELL DEATH DIFFER 2019 10.1038/s41418-019-0282-0

Ly6G(+) inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model

Jeon¹, HY; Ham, SW; Kim, JK; Jin, X; Lee, SY; Shin, YJ; Choi, CY; Sa, JK; Kim, SH; Chun, T; Jin, X; Nam, DH; Kim, H

J NEUROSURG 2019 10.3171/2018.6.JNS181099

Endoscopic transorbital surgery for Meckel's cave and middle cranial fossa tumors: surgical technique and early results

Jeon¹, C; Hong, CK; Woo, KI; Hong, SD; Nam, DH; Lee, JI; Choi, JW; Seol, HJ; Kong, DS

J NEUROSURG 2019 10.3171/2018.3.JNS173233

Clinical and ophthalmological outcome of endoscopic transorbital surgery for cranioorbital tumors

Kong¹, DS; Young, SM; Hong, CK; Kim, YD; Hong, SD; Choi, JW; Seol, HJ; Lee, JI; Shin, HJ; Nam, DH; Woo, KI

RSC Adv 2019 10.1039/c9ra04749b

Synthesis and biological evaluation of potent benzoselenophene and heteroaromatic analogues of (S)-1-(chloromethyl)-8-methoxy-2,3-dihydro-1H-benzo[e]indol-5-ol (seco-MCBI)

Mhetre¹, AB; Sreedhar, E; Dubey, R; Sable, GA; Lee, H; Yang, H; Lee, K; Nam, DH; Lim, D

CANCERS 2019 10.3390/cancers11081090

Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models

Lee¹, M; Kim, YS; Lee, K; Kang, M; Shin, H; Oh, JW; Koo, H; Kim, D; Kim, Y; Kong, DS; Nam, DH; Lee, HW

MEDICINE 2019 10.1097/MD.0000000000016089

Differentiation of postoperative changes and residual tumors in dynamic contrast-enhanced sella MRI after transsphenoidal resection of pituitary adenoma

Kim¹, H; Kim, ST; Kim, HJ; Jeon, P; Byun, HS; Kim, YK; Cha, J; Park, GM; Nam, DH; Kong, DS

LARYNGOSCOPE 2019 10.1002/lary.27630

Quality of life after extended versus transsellar endoscopic skull base surgery from 767 patients

Seo¹, MY; Nam, DH; Kong, DS; Lee, JJ; Ryu, G; Kim, HY; Dhong, HJ; Chung, SK; Lee, KE; Hong, SD

INT J CANCER 2019 10.1002/ijc.32054

Hypermutagenesis in untreated adult gliomas due to inherited mismatch mutations

Sa¹, JK; Choi, SW; Zhao, JF; Lee, Y; Zhang, J; Kong, DS; Choi, JW; Seol, HJ; Lee, JI; Iavarone, A; Rabadan, R; Nam, DH

J NEUROSURG 2019 10.3171/2017.12.JNS171943

Clinical and radiological outcomes of proactive Gamma Knife surgery for asymptomatic meningiomas compared with the natural course without intervention

Kim¹, KH; Kang, SJ; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI

WORLD NEUROSURG 2019 10.1016/j.wneu.2019.01.157

Prediction of IDH1 Mutation Status in Glioblastoma Using Machine Learning Technique Based on Quantitative Radiomic Data

Lee¹, MH; Kim, J; Kim, ST; Shin, HM; You, HJ; Choi, JW; Seol, HJ; Nam, DH; Lee, JI; Kong, DS

SCI REP-UK 2019 10.1038/s41598-019-43173-y

Relevance of a TCGA-derived Glioblastoma Subtype Gene-Classifier among Patient Populations

Teo¹, WY; Sekar, K; Seshachalam, P; Shen, JH; Chow, WY; Lau, CC; Yang, H; Park, J; Kang, SG; Li, XN; Nam, DH; Hui, KM

J EXP MED 2019 10.1084/jem.20172170

PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma

Shin¹, YJ; Sa, JK; Lee, Y; Kim, D; Chang, N; Cho, HJ; Son, M; Oh, MYT; Shin, K; Lee, JK; Park, J; Jo, YK; Kim, M; Paddison, PJ; Tergaonkar, V; Lee, J; Nam, DH

PLoS One 2019 10.1371/journal.pone.0215080

Selective colony area method for heterogeneous patient-derived tumor cell lines in anti-cancer drug screening system

Cho¹, JH; Kim, JS; Kim, ST; Hong, JY; Park, JO; Park, YS; Nam, DH; Lee, DW; Lee, J

INT J MOL SCI 2019 10.3390/ijms20071717

Elucidation of Novel Therapeutic Targets for Acute Myeloid Leukemias with RUNX1-RUNX1T1 Fusion

Yun¹, JW; Bae, YK; Cho, SY; Koo, H; Kim, HJ; Nam, DH; Kim, SH; Chun, S; Joo, KM; Park, WY

J NEUROSURG 2019 10.3171/2017.11.JNS171337

Selection of endoscopic or transcranial surgery for tuberculum sellae meningiomas according to specific anatomical features: a retrospective multicenter analysis (KOSEN-002)

Kong¹, DS; Hong, CK; Hong, SD; Nam, DH; Lee, JI; Seol, HJ; Oh, J; Kim, DG; Kim, YH

Front Immunol 2019 10.3389/fimmu.2019.00555

Preferential Infiltration of Unique V gamma 9J gamma 2-V delta 2 T Cells Into Glioblastoma Multiforme

Lee¹, M; Park, C; Woo, J; Kim, J; Kho, I; Nam, DH; Park, WY; Kim, YS; Kong, DS; Lee, HW; Kim, TJ

WORLD NEUROSURG 2019 10.1016/j.wneu.2018.11.090

Endoscopic Endonasal Versus Transorbital Surgery for Middle Cranial Fossa Tumors: Comparison of Clinical Outcomes Based on Surgical Corridors

Lee¹, MH; Hong, SD; Woo, KI; Kim, YD; Choi, JW; Seol, HJ; Lee, JI; Shin, HJ; Nam, DH; Kong, DS

WORLD NEUROSURG 2019 10.1016/j.wneu.2018.10.151

Apparent Diffusion Coefficient as a Predictive Biomarker for Survival in Patients with Treatment-Naive Glioblastoma Using Quantitative Multiparametric Magnetic Resonance Profiling

Kim¹, BS; Kim, ST; Kim, JH; Seol, HJ; Nam, DH; Shin, HJ; Lee, JI; Kong, DS

RADIOTHER ONCOL 2019 10.1016/j.radonc.2018.11.025

Cancer genetic markers according to radiotherapeutic response in patients with primary glioblastoma - Radiogenomic approach for precision medicine

Yang¹, K; Jung, SW; Shin, H; Lim, DH; Lee, JI; Kong, DS; Seol, HJ; Kim, ST; Nam, DH

NEURO-ONCOLOGY 2019 10.1093/neuonc/noy105

Identification of genomic and molecular traits that present therapeutic vulnerability to HGF-targeted therapy in glioblastoma

Sa¹, JK; Kim, SH; Lee, JK; Cho, HJ; Shin, YJ; Shin, H; Koo, H; Kim, D; Lee, M; Kang, W; Hong, SH; Kim, JY; Park, YW; Song, SW; Lee, SJ; Joo, KM; Nam, DH

CELL DEATH DIFFER 2019 10.1038/s41418-018-0126-3

TP53 gain-of-function mutation promotes inflammation in glioblastoma

Ham¹, SW; Jeon, HY; Jin, X; Kim, EJ; Kim, JK; Shin, YJ; Lee, Y; Kim, SH; Lee, SY; Seo, S; Park, MG; Kim, HM; Nam, DH; Kim, H

CELL REP 2019 10.1016/j.celrep.2019.01.076

Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation

Minata¹, M; Audia, A; Shi, JF; Lu, SJ; Bernstock, J; Pavlyukov, MS; Das, A; Kim, SH; Shin, YJ; Lee, Y; Koo, H; Snigdha, K; Waghmare, I; Guo, X; Mohyeldin, A; Gallego-Perez, D; Wang, J; Chen, DQ; Cheng, P; Mukheef, F; Contreras, M; Reyes, JF; Vaillant, B; Sulman, EP; Cheng, SY; Markert, JM; Tannous, BA; Lu, XH; Kango-Singh, M; Lee, LJ; Nam, DH; Nakano, I; Bhat, KP

NAT MED 2019 10.1038/s41591-018-0263-8

The molecular landscape of glioma in patients with Neurofibromatosis 1

D'Angelo¹, F; Ceccarelli, M; Tala; Garofano, L; Zhang, J; Frattini, V; Caruso, FP; Lewis, G; Alfaro, KD; Bauchet, L; Berzero, G; Cachia, D; Cangiano, M; Capelle, L; de Groot, J; DiMeco, F; Ducray, F; Farah, W; Finocchiaro, G; Goutagny, S; Kamiya-Matsuoka, C; Lavarino, C; Loiseau, H; Lorgis, V; Marras, CE; McCutcheon, I; Nam, DH; Ronchi, S; Saletti, V; Seizeur, R; Slopis, J; Sunol, M; Vandenbos, F; Varlet, P; Vidaud, D; Watts, C; Tabar, V; Reuss, DE; Kim, SK; Meyronet, D; Mokhtari, K; Salvador, H; Bhat, KP; Eoli, M; Sanson, M; Lasorella, A; Iavarone, A

NEURO-ONCOLOGY 2019 10.1093/neuonc/noy123

Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma

Cho¹, HJ; Zhao, JF; Jung, SW; Ladewig, E; Kong, DS; Suh, YL; Lee, Y; Kim, D; Ahn, SH; Bordyuh, M; Kang, HJ; Sa, JK; Seo, YJ; Kim, ST; Lim, DH; Dho, YS; Lee, JI; Seol, HJ; Choi, JW; Park, WY; Park, CK; Rabadan, R; Nam, DH

J NEUROSURG 2018 10.3171/2017.7.JNS171226

Clinical outcomes of intracranial solitary fibrous tumor and hemangiopericytoma: analysis according to the 2016 WHO classification of central nervous system tumors

Kim¹, BS; Kim, Y; Kong, DS; Nam, DH; Lee, JI; Suh, YL; Seol, HJ

NEURORADIOLOGY 2018 10.1007/s00234-018-2091-4

Radiomics features to distinguish glioblastoma from primary central nervous system lymphoma on multi-parametric MRI

Kim¹, Y; Cho, HH; Kim, ST; Park, H; Nam, D; Kong, DS

ACTA NEUROCHIR 2018 10.1007/s00701-018-3726-2

The influence of histology on the response of brain metastases to gamma knife radiosurgery: a propensity score-matched study

Kim¹, KH; Lee, MH; Cho, KR; Choi, JW; Kong, DS; Seol, HJ; Nam, DH; Lee, JI

RADIOTHER ONCOL 2018 10.1016/j.radonc.2018.09.001

Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study

Wee¹, CW; Kim, IH; Park, CK; Kim, JW; Dho, YS; Ohka, F; Aoki, K; Motomura, K; Natsume, A; Kim, N; Suh, CO; Chang, JH; Kim, SH; Cho, WK; Lim, DH; Nam, DH; Choi, JW; Kim, IA; Kim, CY; Oh, YT; Cho, O; Chung, WK; Kim, SH; Kim, E

CELL 2018 10.1016/j.cell.2018.09.038

Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

Hu¹, HM; Mu, QH; Bao, ZS; Chen, YY; Liu, YW; Chen, J; Wang, KY; Wang, Z; Nam, Y; Jiang, BB; Sa, JK; Cho, HJ; Her, NG; Zhang, CB; Zhao, Z; Zhang, Y; Zeng, F; Wu, F; Kang, X; Liu, YQ; Qian, ZH; Wang, ZL; Huang, RY; Wang, QW; Zhang, W; Qiu, XG; Li, WB; Nam, DH; Fan, XL; Wang, JG; Jiang, T

NAT CELL BIOL 2018 10.1038/s41556-018-0183-3

A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma

Barnes¹, JM; Kaushik, S; Bainer, RO; Sa, JK; Woods, EC; Kai, F; Przybyla, L; Lee, M; Lee, HW; Tung, JC; Maller, O; Barrett, AS; Lu, KV; Lakins, JN; Hansen, KC; Obernier, K; Alvarez-Buylla, A; Bergers, G; Phillips, JJ; Nam, DH; Bertozzi, CR; Weaver, VM

ASIA-PAC J CLIN ONCO 2018 10.1111/ajco.12861

Leptomeningeal enhancement on preoperative brain MRI in patients with glioblastoma and its clinical impact

Kim¹, H; Lim, DH; Kim, TG; Lee, JI; Nam, DH; Seol, HJ; Kong, DS; Choi, JW; Suh, YL; Kim, ST

NAT GENET 2018 10.1038/s41588-018-0209-6

Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy

Lee¹, JK; Liu, ZQ; Sa, JK; Shin, S; Wang, JG; Bordyuh, M; Cho, H; Elliott, O; Chu, T; Choi, SW; Rosenbloom, DIS; Lee, IH; Shin, YJ; Kang, HJ; Kim, D; Kim, SY; Sim, MH; Kim, J; Lee, T; Seo, YJ; Shin, H; Lee, M; Kim, SH; Kwon, YJ; Oh, JW; Song, M; Kim, M; Kong, DS; Choi, JW; Seol, HJ; Lee, JI; Kim, ST; Park, JO; Kim, KM; Song, SY; Lee, JW; Kim, HC; Lee, JE; Choi, MG; Seo, SW; Shim, YM; Zo, JI; Jeong, BC; Yoon, Y; Ryu, GH; Kim, NKD; Bae, JS; Park, WY; Lee, J; Verhaak, RGW; Iavarone, A; Lee, J; Rabadan, R; Nam, DH

INVEST NEW DRUG 2018 10.1007/s10637-017-0547-8

Drug repurposing screening identifies bortezomib and panobinostat as drugs targeting cancer associated fibroblasts (CAFs) by synergistic induction of apoptosis

Lee¹, HM; Lee, E; Yeo, SY; Shin, S; Park, HK; Nam, DH; Kim, SH

PLoS One 2018 10.1371/journal.pone.0202307

In vivo distribution of U87MG cells injected into the lateral ventricle of rats with spinal cord injury

Won¹, JS; Nam, H; Lee, HW; Hwang, JY; Noh, YJ; Nam, DH; Lee, SH; Joo, KM

STEM CELL RES 2018 10.1016/j.scr.2018.07.006

Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury

Lee¹, KH; Pyeon, HJ; Nam, H; Won, JS; Hwang, JY; Lee, KA; Yeon, JY; Hong, SC; Nam, DH; Lee, K; Lee, SH; Joo, KM

ANAL CHEM 2018 10.1021/acs.analchem.7b05328

3D Cell-Based High-Content Screening (HCS) Using a Micropillar and Microwell Chip Platform

Lee¹, SY; Doh, I; Nam, DH; Lee, DW

CANCER CELL 2018 10.1016/j.ccell.2018.05.012

Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors

Pavlyukov¹, MS; Yu, H; Bastola, S; Minata, M; Shender, VO; Lee, Y; Zhang, SJ; Wang, J; Komarova, S; Wang, J; Yamaguchi, S; Alsheikh, HA; Shi, JF; Chen, DQ; Mohyeldin, A; Kim, SH; Shin, YJ; Anufrieva, K; Evtushenko, EG; Antipova, NV; Arapidi, GP; Govorun, V; Pestov, NB; Shakhparonov, MI; Lee, LJ; Nam, DH; Nakano, I

CELL DEATH DIS 2018 10.1038/s41419-018-0825-1

Potent effect of the MDM2 inhibitor AMG232 on suppression of glioblastoma stem cells

Her¹, NG; Oh, JW; Oh, YJ; Han, S; Cho, HJ; Lee, Y; Ryu, GH; Nam, DH

J Cancer 2018 10.7150/jca.26256

NCOA4-RET fusion in colorectal cancer: Therapeutic challenge using patient-derived tumor cell lines

Kim¹, SY; Oh, SO; Kim, K; Lee, J; Kang, S; Kim, KM; Lee, W; Kim, ST; Nam, DN

NEURO-ONCOLOGY 2018 10.1093/neuonc/noy020

Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium

Aldape¹, K; Amin, SB; Ashley, DM; Barnholtz-Sloan, JS; Bates, AJ; Beroukhim, R; Bock, C; Brat, DJ; Claus, EB; Costello, JF; de Groot, JF; Finocchiaro, G; French, PJ; Gan, HK; Griffith, B; Herold-Mende, CC; Horbinski, C; Iavarone, A; Kalkanis, SN; Karabatsou, K; Kim, H; Kouwenhoven, MCM; McDonald, KL; Miletic, H; Nam, DH; Ng, HK; Niclou, SP; Noushmehr, H; Ormond, DR; Poisson, LM; Reifenberger, G; Roncaroli, F; Sa, JK; Smitt, PAES; Smits, M; Souza, CF; Tabatabai, G; Van Meir, EG; Verhaak, RGW; Watts, C; Wesseling, P; Woehrer, A; Yung, WKA; Jungk, C; Hau, AC; van Dyck, E; Westerman, BA; Yin, JL; Abiola, O; Zeps, N; Grimmond, S; Buckland, M; Khasraw, M; Sulman, EP; Muscat, AM; Stead, L

CANCER RES TREAT 2018 10.4143/crt.2017.315

Anti-SEMA3A Antibody: A Novel Therapeutic Agent to Suppress Glioblastoma Tumor Growth

Lee¹, J; Shin, YJ; Lee, K; Cho, HJ; Sa, JK; Lee, SY; Kim, SH; Lee, J; Yoon, Y; Nam, DH

ONCOGENE 2018 10.1038/s41388-018-0182-7

Astrocyte-derived CCL20 reinforces HIF-1-mediated hypoxic responses in glioblastoma by stimulating the CCR6-NF-kappa B signaling pathway

Jin¹, P; Shin, SH; Chun, YS; Shin, HW; Shin, YJ; Lee, Y; Kim, D; Nam, DH; Park, JW

NAT GENET 2018 10.1038/s41588-018-0105-0

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

deCarvalho¹, AC; Kim, H; Poisson, LM; Winn, ME; Mueller, C; Cherba, D; Koeman, J; Seth, S; Protopopov, A; Felicella, M; Zheng, SY; Multani, A; Jiang, YY; Zhang, JH; Nam, DH; Petricoin, EF; Chin, L; Mikkelsen, T; Verhaak, RGW

MED ONCOL 2018 10.1007/s12032-018-1119-2

Comparison of 1p and 19q status of glioblastoma by whole exome sequencing, array-comparative genomic hybridization, and fluorescence in situ hybridization

Sim¹, J; Nam, DH; Kim, Y; Lee, IH; Choi, JW; Sa, JK; Suh, YL

Cancer Med 2018 10.1002/cam4.1439

Identification of transcriptome signature for predicting clinical response to bevacizumab in recurrent glioblastoma

Choi¹, SW; Shin, H; Sa, JK; Cho, HJ; Koo, H; Kong, DS; Seol, HJ; Nam, DH

ANTICANCER RES 2018 10.21873/anticanres.12524

Pharmacokinetics, Biodistribution, and Toxicity Evaluation of Anti-SEMA3A (F11) in In Vivo Models

Lee¹, J; Kim, D; Son, E; Yoo, SJ; Sa, JK; Shin, YJ; Yoon, Y; Nam, DH

J NEUROSURG 2018 10.3171/2016.12.JNS161920

Clinical outcomes of an endoscopic transclival and transpetrosal approach for primary skull base malignancies involving the clivus

Kim¹, YH; Jeon, C; Se, YB; Hong, SD; Seol, HJ; Lee, JI; Park, CK; Kim, DG; Jung, HW; Han, DH; Nam, DH; Kong, DS

TRANSL ONCOL 2018 10.1016/j.tranon.2017.10.002

Genetic and Clinical Characteristics of Phyllodes Tumors of the Breast

Kim¹, JY; Yu, JH; Nam, SJ; Kim, SW; Lee, SK; Park, WY; Noh, DY; Nam, DH; Park, YH; Han, W; Lee, JE

AM J CLIN ONCOL-CANC 2018 10.1097/COC.0000000000000224

Prognostic Value of Ki-67 Labeling Index and Postoperative Radiotherapy in WHO Grade II Meningioma

Choi¹, Y; Lim, DH; Yu, JI; Jo, K; Nam, DH; Seol, HJ; Lee, JI; Kong, DS; Suh, YL; Nam, H

ONCOL LETT 2017 10.3892/ol.2017.7196

Preclinical and clinical implications of TERT promoter mutation in glioblastoma multiforme

Jeong¹, DE; Woo, SR; Nam, H; Nam, DH; Lee, JH; Joo, KM

BIOCHEM BIOPH RES CO 2017 10.1016/j.bbrc.2017.09.061

Antitumor activity, pharmacokinetics, tumor-homing effect, and hepatotoxicity of a species cross-reactive c-Met antibody

Park¹, H; Kim, D; Son, E; Shin, S; Sa, JK; Kim, SH; Yoon, Y; Nam, DH

J CLIN NEUROSCI 2017 10.1016/j.jocn.2017.07.012

Reconstructive outcome of intraoperative cerebrospinal fluid leak after endoscopic endonasal surgery for tumors involving skull base

Jeon¹, CM; Hong, SD; Seol, HJ; Lee, JI; Nam, DH; Hwang, YJ; Kong, DS

MOL CELL BIOL 2017 10.1128/MCB.00265-17

RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer

Lee¹, JH; Jeon, YG; Lee, KH; Lee, HW; Park, J; Jang, H; Kang, M; Lee, HS; Cho, HJ; Nam, DH; Kwak, C; Kim, JB

BIOMED RES INT 2017 10.1155/2017/7218707

High-Dose Compound Heat Map for 3D-Cultured Glioblastoma Multiforme Cells in a Micropillar and Microwell Chip Platform

Lee¹, DW; Lee, SY; Doh, I; Ryu, GH; Nam, DH

INT J MOL SCI 2017 10.3390/ijms18091968

Tumor Inhibitory Effect of IRCR201, a Novel Cross-Reactive c-Met Antibody Targeting the PSI Domain

Park¹, H; Kim, D; Kim, E; Sa, JK; Lee, HW; Yu, S; Oh, J; Kim, SH; Yoon, Y; Nam, DH

Clin Neuroradiol 2017 10.1007/s00062-016-0508-1

Differentiation of Hemangioblastoma from Metastatic Brain Tumor using Dynamic Contrast-enhanced MR Imaging

Cha¹, J; Kim, ST; Nam, DH; Kong, DS; Kim, HJ; Kim, YK; Kim, HY; Park, GM; Jeon, P; Kim, KH; Byun, HS

CANCER RES 2017 10.1158/0008-5472.CAN-17-0388

Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBP beta Signaling

Yin¹, J; Oh, YT; Kim, JY; Kim, SS; Choi, E; Kim, TH; Hong, JH; Chang, N; Cho, HJ; Sa, JK; Kim, JC; Kwon, HJ; Park, S; Lin, W; Nakano, I; Gwak, HS; Yoo, H; Lee, SH; Lee, J; Kim, JH; Kim, SY; Nam, DH; Park, MJ; Park, JB

ACTA NEUROCHIR 2017 10.1007/s00701-017-3230-0

Optimal treatment of jugular foramen schwannomas: long-term outcome of a multidisciplinary approach for a series of 29 cases in a single institute

Ryu¹, SM; Lee, JI; Park, K; Choi, JW; Kong, DS; Nam, DH; Jeong, HS; Cho, YS; Seol, HJ

NEURO-ONCOLOGY 2017 10.1093/neuonc/nox025

Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG

Blumenthal¹, DT; Gorlia, T; Gilbert, MR; Kim, MM; Nabors, LB; Mason, WP; Hegi, ME; Zhang, PX; Golfinopoulos, V; Perry, JR; Nam, DH; Erridge, SC; Corn, BW; Mirimanoff, RO; Brown, PD; Baumert, BG; Mehta, MP; van den Bent, MJ; Reardon, DA; Weller, M; Stupp, R

WORLD NEUROSURG 2017 10.1016/j.wneu.2017.04.141

Outcome of Endoscopic Transsphenoidal Surgery for Acromegaly

Kim¹, JH; Hur, KY; Lee, JH; Lee, JH; Se, YB; Kim, HI; Lee, SH; Nam, DH; Kim, SY; Kim, KW; Kong, DS; Kim, YH

J CLIN INVEST 2017 10.1172/JCI89092

Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2

Wang¹, J; Cheng, P; Pavlyukov, MS; Yu, H; Zhang, Z; Kim, SH; Minata, M; Mohyeldin, A; Xie, WF; Chen, DQ; Goidts, V; Frett, B; Hu, WH; Li, HY; Shin, YJ; Lee, Y; Nam, DH; Kornblum, HI; Wang, MDD; Nakano, I

MOL CELL ENDOCRINOL 2017 10.1016/j.mce.2017.01.004

The role of STAT3 in glioblastoma progression through dual influences on tumor cells and the immune microenvironment

Chang¹, N; Ahn, SH; Kong, DS; Lee, HW; Nam, DH

J NEURO-ONCOL 2017 10.1007/s11060-017-2478-9

MGMT promoter methylation status as a prognostic factor for the outcome of gamma knife radiosurgery for recurrent glioblastoma

Kim¹, BS; Kong, DS; Seol, HJ; Nam, DH; Lee, JI

CANCER CELL 2017 10.1016/j.ccell.2017.06.003

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment

Wang¹, QH; Hu, BL; Hu, X; Kim, H; Squatrito, M; Scarpace, L; deCarvalho, AC; Lyu, S; Li, PP; Li, Y; Barthel, F; Cho, HJ; Lin, YH; Satani, N; Martinez-Ledesma, E; Zheng, SY; Chang, E; Sauve, CEG; Olar, A; Lan, ZD; Finocchiaro, G; Phillips, JJ; Berger, MS; Gabrusiewicz, KR; Wang, GC; Eskilsson, E; Hu, J; Mikkelsen, T; DePinho, RA; Muller, F; Heimberger, AB; Sulman, EP; Nam, DH; Verhaak, RGW

Nat Genet. 2017 Apr;49(4):594-599. doi: 10.1038/ng.3806. Epub 2017 Mar 6.

Spatiotemporal genomic architecture informs precision oncology in glioblastoma

Lee JK1¹,2, Wang J3,4,5, Sa JK1,2,6, Ladewig E3,4, Lee HO7, Lee IH1,2, Kang HJ1,2, Rosenbloom DS3,4, Camara PG3,4, Liu Z3,4, van Nieuwenhuizen P3,4, Jung SW1,2,6, Choi SW1,2,6, Kim J1,2, Chen A3,4, Kim KT7, Shin S1,2,6, Seo YJ1,2, Oh JM1,2, Shin YJ1,2,7, Park CK8, Kong DS2, Seol HJ2, Blumberg A9, Lee JI2, Iavarone A10,11,12, Park WY6,7, Rabadan R3,4, Nam DH1,2,6.

Org Biomol Chem. 2017 Feb 1;15(5):1198-1208. doi: 10.1039/c6ob02729f.

Synthesis and anticancer activity of benzoselenophene and heteroaromatic derivatives of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI)

Mhetre AB1¹, Lee H1, Yang H2, Lee K2, Nam DH2, Lim D1.

Oncotarget. 2017 Jan 3;8(1):1321-1328. doi: 10.18632/oncotarget.13616.

Genomic and transcriptomic characterization of skull base chordoma

Sa JK1¹,2,3, Lee IH2,3, Hong SD4, Kong DS2,3,5, Nam DH1,2,3,5.

J Korean Neurosurg Soc. 2017 Jan 1;60(1):21-29. doi: 10.3340/jkns.2016.0404.005. Epub 2016 Dec 29.

The Influence of Biomarker Mutations and Systemic Treatment on Cerebral Metastases from NSCLC Treated with Radiosurgery

Lee MH1¹, Kong DS1, Seol HJ1, Nam DH1, Lee JI1.

J Clin Neurosci. 2017 Jan;35:35-41. doi: 10.1016/j.jocn.2016.10.002. Epub 2016 Oct 18.

Gamma knife radiosurgery for residual or recurrent intracranial hemangiopericytomas

Kim BS1¹, Kong DS2, Seol HJ2, Nam DH2, Lee JI3.

Oncotarget. 2017 Jan 24;8(4):7003-7013. doi: 10.18632/oncotarget.12273.

Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in korea

Kong DS1¹, Nam DH1, Kang SH2, Lee JW3, Chang JH4, Kim JH5, Lim YJ6, Koh YC7, Chung YG2, Kim JM8, Kim CH8.

Cancer Res Treat. 2017 Jan;49(1):193-203. doi: 10.4143/crt.2015.473. Epub 2016 Jun 27.

Concurrent Chemoradiotherapy with Temozolomide Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients: A Retrospective Multicenter Observation Study in Korea

Kim BS1¹, Seol HJ2, Nam DH2, Park CK3, Kim IH4, Kim TM5, Kim JH6, Cho YH6, Yoon SM7, Chang JH8, Kang SG8, Kim EH8, Suh CO9, Jung TY10, Lee KH11, Kim CY12, Kim IA13, Hong CK14, Yoo H15, Kim JH16, Kang SH17, Kang MK18, Kim EY19, Kim SH20, Chung DS21, Hwang SC22, Song JH23, Cho SJ24, Lee SI25, Lee YS26, Ahn KJ27, Kim SH28, Lim DH29, Gwak HS30, Lee SH31, Hong YK32.

Oncotarget. 2017 Jan 31;8(5):8342-8355. doi: 10.18632/oncotarget.14184.

MicroRNA-1908-5p contributes to the oncogenic function of the splicing factor SRSF3

Kim HR1¹, Shin CH1, Lee H1, Choi KH1, Nam DH1,2, Ohn T3, Kim HH1,4.

SENSORS AND ACTUATORS B-CHEMICAL, JUN 2 2016, 228:523-528, DOI: 10.1016/j.snb.2016.01.011

Unified 2D and 3D cell-based high-throughput screening platform using a micropillar/microwell chip

Lee DW¹, Doh I, Nam DH

Int J Oncol. 2016 Mar;48(3):1053-62. doi: 10.3892/ijo.2016.3328. Epub 2016 Jan 11.

Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma

Cho YJ1¹, Kang W2, Kim SH3, Sa JK4, Kim N4, Paddison PJ5, Kim M6, Joo KM3, Hwang YI1, Nam DH7.

Histol Histopathol. 2016 Mar;31(3):269-83. doi: 10.14670/HH-11-695. Epub 2015 Nov 18.

Facilitating tailored therapeutic strategies for glioblastoma through an orthotopic patient-derived xenograft platform

Lee HW1¹, Lee K2, Kim DG3, Yang H4, Nam DH5.

Lab Invest. 2016 Feb;96(2):137-50. doi: 10.1038/labinvest.2015.140. Epub 2015 Dec 7.

WNT signaling in glioblastoma and therapeutic opportunities

Lee Y1¹, Lee JK2, Ahn SH1, Lee J3, Nam DH1,4.

Oncol Lett. 2016 Feb;11(2):1281-1286. Epub 2016 Jan 7.

Repurposing antipsychotics as glioblastoma therapeutics: Potentials and challenges

Lee JK1¹, Nam DH1, Lee J2.

Mol Cancer Ther. 2016 Feb;15(2):251-63. doi: 10.1158/1535-7163.MCT-15-0679. Epub 2015 Nov 19.

GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands

Lim Y1¹, Yoo J2, Kim MS1, Hur M3, Lee EH1, Hur HS1, Lee JC1, Lee SN1, Park TW1, Lee K1, Chang KH1, Kim K2, Kang Y2, Hong KW1, Kim SH4, Kim YG5, Yoon Y6, Nam DH7, Yang H8, Kim DG9, Cho HS10, Won J11.

Cancer Med. 2016 Dec;5(12):3615-3621. doi: 10.1002/cam4.955. Epub 2016 Nov 23.

Analysis of risk factors to predict communicating hydrocephalus following gamma knife radiosurgery for intracranial schwannoma

Lee S1¹, Seo SW2, Hwang J1, Seol HJ1, Nam DH1, Lee JI1, Kong DS1.

World Neurosurg. 2016 Nov;95:399-405. doi: 10.1016/j.wneu.2016.08.046. Epub 2016 Aug 24.

Outcomes of Gamma Knife Radiosurgery in Combination with Crizotinib for Patients with Brain Metastasis from Non-Small Cell Lung Cancer

Choi JW1¹, Kong DS1, Seol HJ1, Nam DH1, Yoo KH2, Sun JM2, Ahn JS2, Ahn MJ2, Park K2, Lee JI3.

Neurosurg Rev. 2016 Oct;39(4):643-53. doi: 10.1007/s10143-016-0728-5. Epub 2016 May 4.

Clinical outcome of neurofibromatosis type 2-related vestibular schwannoma: treatment strategies and challenges

Kim BS1¹, Seol HJ2, Lee JI3, Shin HJ3, Park K3, Kong DS3, Nam DH3, Cho YS4.

Neuro Oncol. 2016 Jan;18(1):37-47. doi: 10.1093/neuonc/nov091. Epub 2015 Jun 1.

USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance

Lee JK1¹, Chang N1, Yoon Y1, Yang H1, Cho H1, Kim E1, Shin Y1, Kang W1, Oh YT1, Mun GI1, Joo KM1, Nam DH1, Lee J1.

J Korean Neurosurg Soc. 2016 Jan;59(1):44-51. doi: 10.3340/jkns.2016.59.1.44. Epub 2016 Jan 20.

Malignant Glioma with Neuronal Marker Expression : A Clinicopathological Study of 18 Cases

Kim HR1¹, Lee JJ2, Lee JI3, Nam DH3, Suh YL2, Seol HJ3.

World Neurosurg. 2016 Sep;93:164-7. doi: 10.1016/j.wneu.2016.06.006. Epub 2016 Jun 11.

Nasoseptal Flap Elevation in Patients with History of Septal Surgery: Does It Increase Flap Failure or Cerebrospinal Fluid Leakage?

Park W1¹, Hong SD2, Nam DH3, Kong DS3, Ryu G1, Kim HY1, Chung SK1, Dhong HJ1.

Oncotarget. 2016 Aug 9;7(32):51626-51639. doi: 10.18632/oncotarget.10539.

Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion

Chang N1¹,2,3, Lee HW3,4, Lim JE5, Jeong DE1, Song HJ6, Kim S3,7, Nam DH1,2,3, Sung HH5, Jeong BC5, Seo SI5, Jeon SS5, Lee HM5, Choi HY5, Jeon HG5.

Nat Genet. 2016 Jul;48(7):768-76. doi: 10.1038/ng.3590. Epub 2016 Jun 6.

Clonal evolution of glioblastoma under therapy

Wang J1¹,2, Cazzato E3, Ladewig E1,2, Frattini V4, Rosenbloom DI1,2, Zairis S1,2, Abate F1,2, Liu Z1,2, Elliott O1,2, Shin YJ5, Lee JK5, Lee IH5, Park WY6, Eoli M3, Blumberg AJ7, Lasorella A4,8,9, Nam DH5,10, Finocchiaro G3, Iavarone A4,9,11, Rabadan R1,2.

Medicine (Baltimore). 2016 Jul;95(27):e4109. doi: 10.1097/MD.0000000000004109.

Integrative radiogenomic analysis for genomic signatures in glioblastomas presenting leptomeningeal dissemination

You HJ1¹, Park HY, Kim J, Lee IH, Seol HJ, Lee JI, Kim ST, Kong DS, Nam DH.

PLoS One. 2016 Jul 8;11(7):e0158639. doi: 10.1371/journal.pone.0158639. eCollection 2016.

Sensitive Tumorigenic Potential Evaluation of Adult Human Multipotent Neural Cells Immortalized by hTERT Gene Transduction

Lee KH1¹,2, Nam H3,2, Jeong da E1,2, Kim SS1,2, Song HJ4,2, Pyeon HJ4,2, Kang K4, Hong SC1,2, Nam DH1,3,2, Joo KM1,4,2.

World Neurosurg. 2016 Jun;90:496-503. doi: 10.1016/j.wneu.2016.03.050. Epub 2016 Mar 26.

Serial Re-Expansion of Pituitary Gland Is Associated with Endocrinologic Recovery

Cho KR1¹, Hong SD2, Hur KY3, Kim ST4, Seol HJ1, Lee JI1, Kong DS5, Nam DH6.

Oncotarget. 2016 May 17;7(20):29400-11. doi: 10.18632/oncotarget.8837.

Anti-miR delivery strategies to bypass the blood-brain barrier in glioblastoma therapy

Kim DG1¹,2, Kim KH2, Seo YJ2, Yang H2,3, Marcusson EG4, Son E2,5, Lee K1,2, Sa JK1,2, Lee HW1,2,6, Nam DH1,2,3.

Headache. 2016 Apr 4. doi: 10.1111/head.12801.

Gamma Knife Radiosurgery for Trigeminal Neuralgia Secondary to Benign Lesions

Cho KR1¹, Lee MH1, Im YS1, Kong DS1, Seol HJ1, Nam DH1, Lee JI1.

World Neurosurg. 2016 May;89:215-22. doi: 10.1016/j.wneu.2016.01.038. Epub 2016 Jan 28.

Functional Outcome of the Facial Nerve After Surgery for Vestibular Schwannoma: Prediction of Acceptable Long-Term Facial Nerve Function Based on Immediate Postoperative Facial Palsy

Lee S1¹, Seol HJ2, Park K1, Lee JI1, Nam DH1, Kong DS1, Cho YS3.

Genome Biol. 2016 Apr 29;17:80. doi: 10.1186/s13059-016-0945-9.

Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma

Kim KT1¹, Lee HW2, Lee HO1,3, Song HJ4, Jeong da E5, Shin S5, Kim H6, Shin Y6, Nam DH5,7, Jeong BC8, Kirsch DG9,10, Joo KM11,12, Park WY13,14,15.

Oncotarget. 2016 Mar 8;7(10):11526-38. doi: 10.18632/oncotarget.7115.

Integrative radiogenomic analysis for multicentric radiophenotype in glioblastoma

Kong DS1¹,2,3,4, Kim J2,3,4, Lee IH2,3,4, Kim ST5, Seol HJ1, Lee JI1, Park WY6, Ryu G7, Wang Z7, Ma'ayan A7, Nam DH1,2,3,4.

World Neurosurg. 2016 Mar;87:162-9. doi: 10.1016/j.wneu.2015.12.050. Epub 2015 Dec 28.

Endoscopic Modified Transseptal Transsphenoidal Approach for Maximal Preservation of Sinonasal Quality of Life and Olfaction

Hong SD1¹, Nam DH2, Kong DS3, Kim HY1, Chung SK1, Dhong HJ4.

Cancer Res. 2016 Mar 1;76(5):1044-54. doi: 10.1158/0008-5472.CAN-14-2611. Epub 2015 Dec 16.

Novel Morphologic and Genetic Analysis of Cancer Cells in a 3D Microenvironment Identifies STAT3 as a Regulator of Tumor Permeability Barrier Function

Park MC1¹, Jeong H2, Son SH3, Kim Y4, Han D4, Goughnour PC4, Kang T3, Kwon NH3, Moon HE5, Paek SH5, Hwang D6, Seol HJ7, Nam DH7, Kim S8.

Oncotarget. 2015 Sep 29;6(29):27239-51. doi: 10.18632/oncotarget.4835.

Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme

Kang W1¹,2, Kim SH3, Cho HJ4, Jin J1,2, Lee J5, Joo KM1,4,3, Nam DH4,2.

Cancer Cell. 2015 Sep 14;28(3):318-28. doi: 10.1016/j.ccell.2015.07.013.

Spatiotemporal Evolution of the Primary Glioblastoma Genome

Kim J1¹, Lee IH2, Cho HJ3, Park CK4, Jung YS5, Kim Y6, Nam SH6, Kim BS5, Johnson MD7, Kong DS5, Seol HJ5, Lee JI5, Joo KM8, Yoon Y3, Park WY9, Lee J10, Park PJ11, Nam DH12.

World Neurosurg. 2015 Dec;84(6):1752-7. doi: 10.1016/j.wneu.2015.07.045. Epub 2015 Jul 26.

Effectiveness of Postoperative Gamma Knife Radiosurgery to the Tumor Bed After Resection of Brain Metastases

Choi JW1¹, Im YS1, Kong DS1, Seol HJ1, Nam DH1, Lee JI2.

Cell Rep. 2015 Dec 22;13(11):2425-39. doi: 10.1016/j.celrep.2015.11.021. Epub 2015 Dec 7.

Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells

Toledo CM1¹, Ding Y2, Hoellerbauer P1, Davis RJ3, Basom R4, Girard EJ5, Lee E6, Corrin P2, Hart T7, Bolouri H2, Davison J4, Zhang Q4, Hardcastle J2, Aronow BJ8, Plaisier CL9, Baliga NS9, Moffat J7, Lin Q10, Li XN10, Nam DH11, Lee J12, Pollard SM13, Zhu J6, Delrow JJ4, Clurman BE14, Olson JM15, Paddison PJ16.

BMC Cancer. 2015 Dec 24;15:1011. doi: 10.1186/s12885-015-2034-y.

Natural killer (NK) cells inhibit systemic metastasis of glioblastoma cells and have therapeutic effects against glioblastomas in the brain

Lee SJ1¹, Kang WY2,3, Yoon Y4,5, Jin JY6, Song HJ7, Her JH8, Kang SM9, Hwang YK10, Kang KJ11, Joo KM12,13,14,15, Nam DH16,17.

J Neurooncol. 2015 Nov;125(2):331-8. doi: 10.1007/s11060-015-1915-x. Epub 2015 Sep 15.

Outcome of gamma knife radiosurgery for metastatic brain tumors derived from non-small cell lung cancer

Cho KR1¹, Lee MH1, Kong DS1, Seol HJ1, Nam DH1, Sun JM2, Ahn JS2, Ahn MJ2, Park K2, Kim ST3, Lim do H4, Lee JI5.

MAbs. 2015;7(6):1195-204. doi: 10.1080/19420862.2015.1086854. Epub 2015 Sep 1.

Anticancer activity of TTAC-0001, a fully human anti-vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) monoclonal antibody, is associated with inhibition of tumor angiogenesis

Kim DG1¹,2, Jin Y1, Jin J1, Yang H1,3, Joo KM1,2,4, Lee WS5, Shim SR5, Kim SW5, Yoo J5, Lee SH6, Yoo JS5, Nam DH1,2,3.

PLoS One. 2015 Oct 7;10(10):e0137703. doi: 10.1371/journal.pone.0137703. eCollection 2015.

FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2

Lee Y1¹, Kim KH2, Kim DG1, Cho HJ1, Kim Y3, Rheey J2, Shin K1, Seo YJ4, Choi YS4, Lee JI4, Lee J3, Joo KM5, Nam DH6.

J Biomol Screen. 2015 Oct;20(9):1178-84. doi: 10.1177/1087057115597635. Epub 2015 Aug 3.

Automatic 3D Cell Analysis in High-Throughput Microarray Using Micropillar and Microwell Chips

Lee DW1¹, Lee MY2, Ku B3, Nam DH4.

Eur J Med Chem. 2015 Oct 20;103:210-22. doi: 10.1016/j.ejmech.2015.08.001. Epub 2015 Aug 4.

Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM)

Elkamhawy A1¹, Viswanath AN2, Pae AN2, Kim HY3, Heo JC3, Park WK3, Lee CO3, Yang H4, Kim KH4, Nam DH5, Seol HJ5, Cho H6, Roh EJ7.

J Neurooncol. 2015 Oct;125(1):207-15. doi: 10.1007/s11060-015-1902-2. Epub 2015 Sep 4.

A multicenter study of anaplastic oligodendroglioma: the Korean Radiation Oncology Group Study 13-12

Kang HC1¹, Yu T2, Lim do H3, Kim IH2, Chung WK4, Suh CO5, Choi BO6, Cho KH7, Cho JH8, Kim JH9, Nam DH10, Park CK11, Hong YK12, Kim IA13,14.

Oncotarget. 2015 Oct 20;6(32):33046-64. doi: 10.18632/oncotarget.5422.

Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis

Jeong da E1¹, Song HJ2, Lim S3, Lee SJ4, Lim JE5, Nam DH1,4,6, Joo KM1,2, Jeong BC5, Jeon SS5, Choi HY5, Lee HW4,7.

MAbs. 2015;7(5):957-68. doi: 10.1080/19420862.2015.1045168. Epub 2015 May 5.

TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis

Lee WS1¹, Pyun BJ, Kim SW, Shim SR, Nam JR, Yoo JY, Jin Y, Jin J, Kwon YG, Yun CO, Nam DH, Oh K, Lee DS, Lee SH, Yoo JS.

J Clin Neurosci. 2015 Sep;22(9):1425-9. doi: 10.1016/j.jocn.2015.02.036. Epub 2015 Jun 29.

Prognostic impact of molecular phenotype in patients with recurrent anaplastic glioma treated with prolonged administration of temozolomide

Kong DS1¹, Kim HR2, Choi YR3, Seol HJ1, Lee JI1, Nam DH4.

J Neurooncol. 2015 Aug;124(1):101-10. doi: 10.1007/s11060-015-1808-z. Epub 2015 May 31.

Prognostic implication of progression pattern after anti-VEGF bevacizumab treatment for recurrent malignant gliomas

Kim BS1¹, Kim SK, Choi SH, Lee SH, Seol HJ, Nam DH, Lee JI, Park CK, Kong DS.

Oncotarget. 2015 Aug 21;6(24):20145-59.

In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma

Sa JK1¹,2,3, Yoon Y1, Kim M2,3, Kim Y4, Cho HJ1,2,3, Lee JK2,3, Kim GS3, Han S1,2,3, Kim WJ1,2,3, Shin YJ2,3, Joo KM1,2,3, Paddison PJ5, Ishitani T6, Lee J4, Nam DH1,2,3,7.

Genome Biol. 2015 Jun 19;16:127. doi: 10.1186/s13059-015-0692-3.

Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells

Kim KT1¹,2, Lee HW3,4,5, Lee HO6,7, Kim SC8, Seo YJ9,10, Chung W11,12, Eum HH13,14, Nam DH15,16,17, Kim J18,19, Joo KM20,21,22, Park WY23,24,25.

Oncotarget. 2015 Jun 30;6(18):16059-68.

Correlation between tumor engraftment in patient-derived xenograft models and clinical outcomes in colorectal cancer patients

Oh BY1¹, Lee WY1,2, Jung S3, Hong HK1, Nam DH2,4, Park YA1, Huh JW1, Yun SH1, Kim HC1, Chun HK5, Cho YB1,2,6.

Neuro Oncol. 2015 May;17(5):708-17. doi: 10.1093/neuonc/nou356. Epub 2015 Mar 11.

Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study

Nabors LB1¹, Fink KL1, Mikkelsen T1, Grujicic D1, Tarnawski R1, Nam do H1, Mazurkiewicz M1, Salacz M1, Ashby L1, Zagonel V1, Depenni R1, Perry JR1, Hicking C1, Picard M1, Hegi ME1, Lhermitte B1, Reardon DA1.

Am J Rhinol Allergy. 2015 May-Jun;29(3):221-5. doi: 10.2500/ajra.2015.29.4165.

Endoscopic binostril versus transnasal transseptal microscopic pituitary surgery: Sinonasal quality of life and olfactory function

Hong SD1¹, Nam do H, Seol HJ, Choi NY, Kim HY, Chung SK, Dhong HJ.

Int J Cancer. 2015 May 1;136(9):2065-77. doi: 10.1002/ijc.29248. Epub 2014 Oct 10.

Tpl2 induces castration resistant prostate cancer progression and metastasis

Lee HW1¹, Cho HJ, Lee SJ, Song HJ, Cho HJ, Park MC, Seol HJ, Lee JI, Kim S, Lee HM, Choi HY, Nam DH, Joo KM.

Acta Neurochir (Wien). 2015 Apr;157(4):569-76. doi: 10.1007/s00701-015-2344-5. Epub 2015 Feb 8.

Optimal treatment of leptomeningeal spread in glioblastoma: analysis of risk factors and outcome

Noh JH1¹, Lee MH, Kim WS, Lim do H, Kim ST, Kong DS, Nam DH, Lee JI, Seol HJ.

Clin Cancer Res. 2015 Mar 1;21(5):1172-82. doi: 10.1158/1078-0432.CCR-14-1589. Epub 2014 Dec 30.

Patient-Derived Xenografts from Non-Small Cell Lung Cancer Brain Metastases Are Valuable Translational Platforms for the Development of Personalized Targeted Therapy

Lee HW1¹, Lee JI2, Lee SJ3, Cho HJ2, Song HJ4, Jeong da E5, Seo YJ2, Shin S5, Joung JG6, Kwon YJ7, Choi YL8, Park WY9, Lee HM10, Seol HJ2, Shim YM11, Joo KM12, Nam DH13.

J Clin Neurosci. 2015 Mar;22(3):468-73. doi: 10.1016/j.jocn.2014.09.018. Epub 2015 Jan 13.

Outcome of salvage treatment for recurrent glioblastoma

Kim HR1¹, Kim KH2, Kong DS2, Seol HJ2, Nam DH2, Lim do H3, Lee JI4.

Int J Mol Sci. 2015 Feb 25;16(3):4471-91. doi: 10.3390/ijms16034471.

Tumor Progression Locus 2 (Tpl2) Kinase as a Novel Therapeutic Target for Cancer: Double-Sided Effects of Tpl2 on Cancer

Lee HW1¹,2,3, Choi HY2, Joo KM4,5, Nam DH6,7.

J Neurooncol. 2015 Jan;121(2):311-8. doi: 10.1007/s11060-014-1634-8. Epub 2014 Dec 9.

Outcome of radiosurgery for recurrent malignant gliomas: assessment of treatment response using relative cerebral blood volume

Kim HR1¹, Kim SH, Lee JI, Seol HJ, Nam DH, Kim ST, Park K, Kim JH, Kong DS.

J Neurooncol. 2014 Sep;119(2):405-12. doi: 10.1007/s11060-014-1507-1. Epub 2014 Jun 26.

Efficacy of postoperative radiotherapy for high grade meningiomas

Choi Y1¹, Lim DH, Jo K, Nam DH, Seol HJ, Lee JI.

Acta Neurochir (Wien). 2014 Apr;156(4):641-51. doi: 10.1007/s00701-014-2020-1. Epub 2014 Feb 20.

Outcome of conventional treatment and prognostic factor in elderly glioblastoma patients

Oh SW1¹, Jee TK, Kong DS, Nam DH, Lee JI, Seol HJ.

J Surg Res. 2014 Apr;187(2):502-9. doi: 10.1016/j.jss.2013.11.010. Epub 2013 Nov 15.

Colorectal cancer patient-derived xenografted tumors maintain characteristic features of the original tumors

Cho YB1¹, Hong HK1, Choi YL2, Oh E2, Joo KM3, Jin J4, Nam DH4, Ko YH2, Lee WY5.

Mol Cancer Ther. 2014 Dec;13(12):3049-61. doi: 10.1158/1535-7163.MCT-14-0244. Epub 2014 Oct 13.

RRAD Promotes EGFR-Mediated STAT3 Activation and Induces Temozolomide Resistance of Malignant Glioblastoma

Yeom SY1¹, Nam DH2, Park C3.

Small. 2014 Dec 29;10(24):5098-105. doi: 10.1002/smll.201401074. Epub 2014 Sep 16.

High-Throughput, Miniaturized Clonogenic Analysis of a Limiting Dilution Assay on a Micropillar/Microwell Chip with Brain Tumor Cells

Lee DW1¹, Choi YS, Seo YJ, Lee MY, Jeon SY, Ku B, Nam DH.

Am J Rhinol Allergy. 2014 Nov-Dec;28(6):517-9. doi: 10.2500/ajra.2014.28.4109.

Olfactory outcomes after endoscopic pituitary surgery with nasoseptal "rescue" flaps: Electrocautery versus cold knife

Hong SD1¹, Nam DH, Park J, Kim HY, Chung SK, Dhong HJ.

Onco Targets Ther. 2014 Oct 20;7:1933-44. doi: 10.2147/OTT.S36582. eCollection 2014.

Targeting the epithelial to mesenchymal transition in glioblastoma: the emerging role of MET signaling

Lee JK1¹, Joo KM2, Lee J3, Yoon Y4, Nam DH5.

Genomics. 2014 Oct;104(4):234-41. doi: 10.1016/j.ygeno.2014.07.012. Epub 2014 Jul 25.

Patterns of somatic alterations between matched primary and metastatic colorectal tumors characterized by whole-genome sequencing

Xie T1¹, Cho YB2, Wang K3, Huang D4, Hong HK5, Choi YL6, Ko YH7, Nam DH8, Jin J9, Yang H10, Fernandez J11, Deng S12, Rejto PA13, Lee WY14, Mao M15.

Lancet Oncol. 2014 Sep;15(10):1100-8. doi: 10.1016/S1470-2045(14)70379-1. Epub 2014 Aug 19.

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

Stupp R1¹, Hegi ME2, Gorlia T3, Erridge SC4, Perry J5, Hong YK6, Aldape KD7, Lhermitte B2, Pietsch T8, Grujicic D9, Steinbach JP10, Wick W11, Tarnawski R12, Nam DH13, Hau P14, Weyerbrock A15, Taphoorn MJ16, Shen CC17, Rao N18, Thurzo L19, Herrlinger U8, Gupta T20, Kortmann RD21, Adamska K22, McBain C23, Brandes AA24, Tonn JC25, Schnell O25, Wiegel T26, Kim CY27, Nabors LB28, Reardon DA29, van den Bent MJ30, Hicking C31, Markivskyy A31, Picard M31, Weller M32; European Organisation for Research and Treatment of Cancer (EORTC); Canadian Brain Tumor Consortium; CENTRIC study team.

Mol Cancer. 2014 Sep 12;13:211. doi: 10.1186/1476-4598-13-211.

TopBP1 and Claspin contribute to the radioresistance of lung cancer brain metastases

Choi SH¹, Yang H, Lee SH, Ki JH, Nam DH1, Yoo HY.

Biomed Res Int. 2014;2014:747415. doi: 10.1155/2014/747415. Epub 2014 Sep 10.

KML001, a Telomere-Targeting Drug, Sensitizes Glioblastoma Cells to Temozolomide Chemotherapy and Radiotherapy through DNA Damage and Apoptosis

Woo SR1¹, Ham Y2, Kang W3, Yang H3, Kim S4, Jin J3, Joo KM5, Nam DH2.

PLoS One. 2014 Aug 1;9(8):e103327. doi: 10.1371/journal.pone.0103327. eCollection 2014.

Translational Validation of Personalized Treatment Strategy Based on Genetic Characteristics of Glioblastoma

Oh YT1¹, Cho HJ1, Kim J2, Lee JH3, Rho K3, Seo YJ4, Choi YS4, Jung HJ4, Song HS4, Kong DS5, Seol HJ5, Lee JI5, Yoon Y1, Kim S3, Nam DH6, Joo KM7.

PLoS One. 2014 Mar 19;9(3):e91940. doi: 10.1371/journal.pone.0091940. eCollection 2014.

NTRK1 Fusion in Glioblastoma Multiforme

Kim J1¹, Lee Y2, Cho HJ2, Lee YE2, An J2, Cho GH3, Ko YH4, Joo KM5, Nam DH6.

Nat Chem Biol. 2014 Jan;10(1):29-34. doi: 10.1038/nchembio.1381. Epub 2013 Nov 10.

Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction

Kim DG1¹, Lee JY1, Kwon NH2, Fang P3, Zhang Q4, Wang J3, Young NL5, Guo M3, Cho HY6, Mushtaq AU6, Jeon YH6, Choi JW7, Han JM2, Kang HW8, Joo JE8, Hur Y8, Kang W9, Yang H9, Nam DH9, Lee MS10, Lee JW10, Kim ES11, Moon A11, Kim K2, Kim D2, Kang EJ12, Moon Y12, Rhee KH10, Han BW10, Yang JS13, Han G13, Yang WS2, Lee C14, Wang MW15, Kim S16.

Anal Chem. 2014 Jan 7;86(1):535-42. doi: 10.1021/ac402546b. Epub 2013 Dec 2.

High-Throughput Screening (HTS) of Anticancer Drug Efficacy on a Micropillar/Microwell Chip Platform

Lee DW1¹, Choi YS, Seo YJ, Lee MY, Jeon SY, Ku B, Kim S, Yi SH, Nam DH.

Anticancer Res. 2013 Dec;33(12):5335-42.

Genetically-engineered Human Neural Stem Cells with Rabbit Carboxyl Esterase Can Target CNS Lymphoma

Kang W1¹, Jin J, Yang H, Seol HJ, Kim KH, Lee JI, Kim SU, Joo KM, Nam DH.

Clin Cancer Res. 2013 Nov 1;19(21):5879-89. doi: 10.1158/1078-0432.CCR-13-1181. Epub 2013 Aug 30.

Alpha-Smooth Muscle Actin (ACTA2) Is Required for Metastatic Potential of Human Lung Adenocarcinoma

Lee HW1¹, Park YM, Lee SJ, Cho HJ, Kim DH, Lee JI, Kang MS, Seol HJ, Shim YM, Nam DH, Kim HH, Joo KM.

Mol Cancer Res. 2013 Nov;11(11):1375-86. doi: 10.1158/1541-7786.MCR-13-0101-T. Epub 2013 Aug 27.

Tpl2 Kinase Impacts Tumor Growth and Metastasis of Clear Cell Renal Cell Carcinoma

Lee HW1¹, Joo KM, Lim JE, Cho HJ, Cho HJ, Park MC, Seol HJ, Seo SI, Lee JI, Kim S, Jeong BC, Nam DH.

Clin Exp Metastasis. 2013 Oct;30(7):845-54. doi: 10.1007/s10585-013-9584-7. Epub 2013 Apr 27.

Gene silencing of c-Met leads to brain metastasis inhibitory effects

Lee SJ1¹, Seol HJ, Lee HW, Kang WY, Kang BG, Jin J, Jo MY, Jin Y, Lee JI, Joo KM, Nam DH.

Oncol Rep. 2013 Sep;30(3):1101-6. doi: 10.3892/or.2013.2584. Epub 2013 Jul 3.

Adenosine potentiates the therapeutic effects of neural stem cells expressing cytosine deaminase against metastatic brain tumors

Kang W1¹, Seol HJ, Seong DH, Kim J, Kim Y, Kim SU, Nam DH, Joo KM.

Neuro Oncol. 2013 Aug;15(8):1096-101. doi: 10.1093/neuonc/not069. Epub 2013 Jun 25.

A practical scoring system to determine whether to proceed with surgical resection in recurrent glioblastoma

Park CK1¹, Kim JH, Nam DH, Kim CY, Chung SB, Kim YH, Seol HJ, Kim TM, Choi SH, Lee SH, Heo DS, Kim IH, Kim DG, Jung HW.

Cancer Cell. 2013 Jun 10;23(6):839-52. doi: 10.1016/j.ccr.2013.04.008. Epub 2013 May 16.

Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells

Kim E1¹, Kim M, Woo DH, Shin Y, Shin J, Chang N, Oh YT, Kim H, Rheey J, Nakano I, Lee C, Joo KM, Rich JN, Nam DH, Lee J.

Acta Neurochir (Wien). 2013 Mar;155(3):399-405. doi: 10.1007/s00701-012-1576-x. Epub 2012 Dec 14.

Radiosurgery to palliate symptoms in brain metastases from uterine cervix cancer

Chung SB1¹, Jo KI, Seol HJ, Nam DH, Lee JI.

Lab Invest. 2013 Mar;93(3):344-53. doi: 10.1038/labinvest.2012.180. Epub 2013 Feb 4.

Radiosensitization of brain metastasis by targeting c-MET

Yang H1¹, Lee HW, Kim Y, Lee Y, Choi YS, Kim KH, Jin J, Lee J, Joo KM, Nam DH.

Neuro Oncol. 2013 Feb;15(2):161-71. doi: 10.1093/neuonc/nos299. Epub 2012 Dec 20.

Wnt/beta-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells

Kim KH1¹, Seol HJ, Kim EH, Rheey J, Jin HJ, Lee Y, Joo KM, Lee J, Nam DH.

Exp Neurol. 2013 Feb;240:168-77. doi: 10.1016/j.expneurol.2012.11.021. Epub 2012 Nov 29.

Experimental and clinical factors influencing long-term stable in vitro expansion of multipotent neural cells from human adult temporal lobes

Joo KM1¹, Kang BG, Yeon JY, Cho YJ, An JY, Song HS, Won JH, Kim SJ, Hong SC, Nam DH.

Cancer Discov. 2013 Feb;3(2):198-211. doi: 10.1158/2159-8290.CD-12-0353. Epub 2012 Nov 15.

Cancer-Specific Requirement for BUB1B/BUBR1 in Human Brain Tumor Isolates and Genetically Transformed Cells

Ding Y1¹, Hubert CG, Herman J, Corrin P, Toledo CM, Skutt-Kakaria K, Vazquez J, Basom R, Zhang B, Risler JK, Pollard SM, Nam DH, Delrow JJ, Zhu J, Lee J, DeLuca J, Olson JM, Paddison PJ.

Cell Rep. 2013 Jan 31;3(1):260-73. doi: 10.1016/j.celrep.2012.12.013. Epub 2013 Jan 17.

Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In Situ

Joo KM1¹, Kim J, Jin J, Kim M, Seol HJ, Muradov J, Yang H, Choi YL, Park WY, Kong DS, Lee JI, Ko YH, Woo HG, Lee J, Kim S, Nam DH.

Cancer Lett. 2013 Jan 28;328(2):235-42. doi: 10.1016/j.canlet.2012.09.005. Epub 2012 Sep 27.

Blockade of EGFR signaling promotes glioma stem-like cell invasiveness by abolishing ID3-mediated inhibition of p27(KIP1) and MMP3 expression

Jin X1¹, Jin X, Sohn YW, Yin J, Kim SH, Joshi K, Nam DH, Nakano I, Kim H.

Int J Oncol. 2012 Dec;41(6):2013-20. doi: 10.3892/ijo.2012.1663. Epub 2012 Oct 15.

Genomic copy number alterations associated with the early brain metastasis of non-small cell lung cancer

Lee HW1¹, Seol HJ, Choi YL, Ju HJ, Joo KM, Ko YH, Lee JI, Nam DH.

Mol Cells. 2012 Dec;34(6):523-9. doi: 10.1007/s10059-012-0194-z. Epub 2012 Nov 22.

A new anti-c-met antibody selected by a mechanism-based dual-screening method: Therapeutic potential in cancer

Oh YM1¹, Song YJ, Lee SB, Jeong Y, Kim B, Kim GW, Kim KE, Lee JM, Cho MY, Choi J, Nam DH, Song PH, Cheong KH, Kim KA.

Mol Cell Biol. 2012 Oct;32(20):4237-44. Epub 2012 Aug 20.

Heterogeneous Nuclear Ribonucleoprotein C1/C2 Controls the Metastatic Potential of Glioblastoma by Regulating PDCD4

Park YM1¹, Hwang SJ, Masuda K, Choi KM, Jeong MR, Nam DH, Gorospe M, Kim HH.

Mol Cells. 2012 Sep;34(3):329-34. Epub 2012 Sep 3.

MicroRNA-146a suppresses metastatic activity in brain metastasis

Hwang SJ1¹, Seol HJ, Park YM, Kim KH, Gorospe M, Nam DH, Kim HH.

J Neurosci Res. 2012 Sep;90(9):1794-802. doi: 10.1002/jnr.23063. Epub 2012 Apr 26.

Therapeutic effects of human adipose stem cell-conditioned medium on stroke

Cho YJ1¹, Song HS, Bhang S, Lee S, Kang BG, Lee JC, An J, Cha CI, Nam DH, Kim BS, Joo KM.

Cancer Res. 2012 Aug 1;72(15):3828-38. Epub 2012 May 22.

MET Signaling Regulates Glioblastoma Stem Cells

Joo KM1¹, Jin J, Kim E, Ho Kim K, Kim Y, Gu Kang B, Kang YJ, Lathia JD, Cheong KH, Song PH, Kim H, Seol HJ, Kong DS, Lee JI, Rich JN, Lee J, Nam DH.

Mol Med Rep. 2012 Jul;6(1):88-92. doi: 10.3892/mmr.2012.868. Epub 2012 Apr 11.

Combined therapy of temozolomide and ZD6474 (vandetanib) effectively reduces glioblastoma tumor volume through anti-angiogenic and anti-proliferative mechanisms

Jo MY1¹, Kim YG, Kim Y, Lee SJ, Kim MH, Joo KM, Kim HH, Nam DH.

Brain. 2012 Apr;135(Pt 4):1055-69. doi: 10.1093/brain/aws028. Epub 2012 Mar 20.

Interferon regulatory factor 7 regulates glioma stem cells via interleukin-6 and Notch signalling

Jin X1¹, Kim SH, Jeon HM, Beck S, Sohn YW, Yin J, Kim JK, Lim YC, Lee JH, Kim SH, Kang SH, Pian X, Song MS, Park JB, Chae YS, Chung YG, Lee SH, Choi YJ, Nam DH, Choi YK, Kim H.

Int J Oncol. 2012 Apr;40(4):1122-32. doi: 10.3892/ijo.2011.1302. Epub 2011 Dec 15.

Identification of prognostic biomarkers for glioblastomas using protein expression profiling

Jung Y1¹, Joo KM, Seong DH, Choi YL, Kong DS, Kim Y, Kim MH, Jin J, Suh YL, Seol HJ, Shin CS, Lee JI, Kim JH, Song SY, Nam DH.

Lab Invest. 2012 Mar;92(3):466-73. doi: 10.1038/labinvest.2011.161. Epub 2011 Nov 14.

Wnt activation is implicated in glioblastoma radioresistance

Kim Y1¹, Kim KH, Lee J, Lee YA, Kim M, Lee SJ, Park K, Yang H, Jin J, Joo KM, Lee J, Nam DH.

Biochem Biophys Res Commun. 2012 Feb 10;418(2):359-65. doi: 10.1016/j.bbrc.2012.01.026. Epub 2012 Jan 17.

Replacement of microglial cells using Clodronate liposome and bone marrow transplantation in the central nervous system of SOD1(G93A) transgenic mice as an in vivo model of amyotrophic lateral sclerosis

Lee JC1¹, Seong J, Kim SH, Lee SJ, Cho YJ, An J, Nam DH, Joo KM, Cha CI.

PLoS One. 2012;7(2):e25936. doi: 10.1371/journal.pone.0025936. Epub 2012 Feb 10.

Trans-Differentiation of Neural Stem Cells: A Therapeutic Mechanism Against the Radiation Induced Brain Damage

Joo KM1¹, Jin J, Kang BG, Lee SJ, Kim KH, Yang H, Lee YA, Cho YJ, Im YS, Lee DS, Lim DH, Kim DH, Um HD, Lee SH, Lee JI, Nam DH.

Cancer Lett. 2011 Dec 8;311(2):152-9. doi: 10.1016/j.canlet.2011.07.001. Epub 2011 Jul 14.

Genetically engineered human neural stem cells with rabbit carboxyl esterase can target brain metastasis from breast cancer

Seol HJ1¹, Jin J, Seong DH, Joo KM, Kang W, Yang H, Kim J, Shin CS, Kim Y, Kim KH, Kong DS, Lee JI, Aboody KS, Lee HJ, Kim SU, Nam DH.

Bioconjug Chem. 2011 Dec 21;22(12):2568-72. doi: 10.1021/bc200406n. Epub 2011 Nov 28.

In Vivo Specific Delivery of c-Met siRNA to Glioblastoma Using Cationic Solid Lipid Nanoparticles

Jin J1¹, Bae KH, Yang H, Lee SJ, Kim H, Kim Y, Joo KM, Seo SW, Park TG, Nam DH.

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Mild generation of selenolate nucleophiles by thiol reduction of diselenides: convenient syntheses of selenyl-substituted aryl aldehydes

Cancer Res. 2011 Nov 15;71(22):7125-34. doi: 10.1158/0008-5472.CAN-11-1330. Epub 2011 Oct 5.

EGFR-AKT-Smad Signaling Promotes Formation of Glioma Stem-like Cells and Tumor Angiogenesis by ID3-Driven Cytokine Induction

Jin X1¹, Yin J, Kim SH, Sohn YW, Beck S, Lim YC, Nam DH, Choi YJ, Kim H.

Biomaterials. 2011 Nov;32(33):8518-28. doi: 10.1016/j.biomaterials.2011.07.048. Epub 2011 Aug 30.

Identification of a peptide that interacts with Nestin protein expressed in brain cancer stem cells

Beck S1¹, Jin X, Yin J, Kim SH, Lee NK, Oh SY, Jin X, Kim MK, Kim EB, Son JS, Kim SC, Nam DH, Kim SH, Kang SK, Kim H, Choi YJ.

Oncol Res. 2011;19(8-9):381-90.

The Expression of DNA Damage Checkpoint Proteins and Prognostic Implication in Metastatic Brain Tumors

Seol HJ1¹, Yoo HY, Jin J, Joo KM, Kim HS, Yoon SJ, Choi SH, Kim Y, Pyo HR, Lim DH, Kim W, Um HD, Kim JH, Lee JI, Nam DH.

Oncol Rep. 2011 Aug;26(2):423-30. doi: 10.3892/or.2011.1325. Epub 2011 May 26.

Prognostic implications of the DNA damage response pathway in glioblastoma

Seol HJ1¹, Yoo HY, Jin J, Joo KM, Kong DS, Yoon SJ, Yang H, Kang W, Lim DH, Park K, Kim JH, Lee JI, Nam DH.

Exp Mol Med. 2011 Jul 30;43(7):419-26. doi: 10.3858/emm.2011.43.7.046.

Time-course analysis of DNA damage response-related genes after in vitro radiation in H460 and H1229 lung cancer cell lines

Kim KH1¹, Yoo HY, Joo KM, Jung Y, Jin J, Kim Y, Yoon SJ, Choi SH, Seol HJ, Park WY, Nam do H.

J Neurooncol. 2011 Jul;103(3):595-602. doi: 10.1007/s11060-010-0427-y. Epub 2010 Nov 4.

Radiotherapy followed by adjuvant temozolomide with or without neoadjuvant ACNU-CDDP chemotherapy in newly diagnosed glioblastomas: a prospective randomized controlled multicenter phase III trial

Kim IH1¹, Park CK, Heo DS, Kim CY, Rhee CH, Nam DH, Lee SH, Han JH, Lee SH, Kim TM, Kim DW, Kim JE, Paek SH, Kim DG, Kim IA, Kim YJ, Kim JH, Park BJ, Jung HW.

Mol Ther. 2011 Jun;19(6):1161-9. doi: 10.1038/mt.2011.28. Epub 2011 Mar 8.

hMSC-mediated Concurrent Delivery of Endostatin and Carboxylesterase to Mouse Xenografts Suppresses Glioma Initiation and Recurrence

Yin J1¹, Kim JK, Moon JH, Beck S, Piao D, Jin X, Kim SH, Lim YC, Nam DH, You S, Kim H, Choi YJ.

Cancer Res. 2011 Apr 15;71(8):3066-75. doi: 10.1158/0008-5472.CAN-10-1495. Epub 2011 Mar 1.

Frizzled 4 Regulates Stemness and Invasiveness of Migrating Glioma Cells Established by Serial Intracranial Transplantation

Jin X1¹, Jeon HY, Joo KM, Kim JK, Jin J, Kim SH, Kang BG, Beck S, Lee SJ, Kim JK, Park AK, Park WY, Choi YJ, Nam DH, Kim H.

Preparation of blood-brain barrier-permeable paclitaxel-carrier conjugate and its chemotherapeutic activity in the mouse glioblastoma model

Biochem Biophys Res Commun. 2011 Mar 4;406(1):53-8. doi: 10.1016/j.bbrc.2011.01.106. Epub 2011 Feb 1.

Inhibition of checkpoint kinase 1 sensitizes lung cancer brain metastases to radiotherapy

Yang H1¹, Yoon SJ, Jin J, Choi SH, Seol HJ, Lee JI, Nam DH, Yoo HY.

Mol Cells. 2010 Nov;30(5):403-8. doi: 10.1007/s10059-010-0122-z. Epub 2010 Aug 31.

The Neural Stem Cell Fate Determinant TLX Promotes Tumorigenesis and Genesis of Cells Resembling Glioma Stem Cells (vol 30, pg 403, 2010)

Park HJ1¹, Kim JK, Jeon HM, Oh SY, Kim SH, Nam DH, Kim H.

AJNR Am J Neuroradiol. 2011 Feb;32(2):382-7. doi: 10.3174/ajnr.A2286. Epub 2011 Jan 20.

Diagnostic Dilemma of Pseudoprogression in the Treatment of Newly Diagnosed Glioblastomas: The Role of Assessing Relative Cerebral Blood Flow Volume and Oxygen-6-Methylguanine-DNA Methyltransferase Promoter Methylation Status

Kong DS1¹, Kim ST, Kim EH, Lim DH, Kim WS, Suh YL, Lee JI, Park K, Kim JH, Nam DH.

Mol Cells. 2011 Jan;31(1):9-15. doi: 10.1007/s10059-011-0008-8. Epub 2010 Dec 24.

Telomerase activity-independent function of TERT allows glioma cells to attain cancer stem cell characteristics by inducing EGFR expression

Beck S1¹, Jin X, Sohn YW, Kim JK, Kim SH, Yin J, Pian X, Kim SC, Nam DH, Choi YJ, Kim H.

Oncol Rep. 2011 Jan;25(1):33-9.

Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma

Jin J1¹, Joo KM, Lee SJ, Jo MY, Kim Y, Jin Y, Kim JK, Ahn JM, Yoon MJ, Lim J, Nam DH.

Oncol Rep. 2011 Jan;25(1):63-8.

Combined treatment of tumor-tropic human neural stem cells containing the CD suicide gene effectively targets brain tumors provoking a mild immune response

Lee SJ1¹, Kim Y, Jo MY, Kim HS, Jin Y, Kim SU, Jin J, Joo KM, Nam DH.

Neurol Res. 2011 Jan;33(1):33-7. doi: 10.1179/016164110X12807570509899. Epub 2010 Aug 31.

Functional neural stem cell isolation from brains of adult mutant SOD1 (SOD1(G93A)) transgenic amyotrophic lateral sclerosis (ALS) mice

Lee JC1¹, Jin Y, Jin J, Kang BG, Nam DH, Joo KM, Cha CI.

Cancer Res. 2010 Dec 1;70(23):9730-41. doi: 10.1158/0008-5472.CAN-10-1882. Epub 2010 Nov 23.

Negative Regulation of p53 by the Long Isoform of ErbB3 Binding Protein Ebp1 in Brain Tumors

Kim CK1¹, Nguyen TL, Joo KM, Nam DH, Park J, Lee KH, Cho SW, Ahn JY.

Cancer Res. 2010 Dec 15;70(24):10411-21. doi: 10.1158/0008-5472.CAN-10-2591. Epub 2010 Nov 5.

CXCR4 Signaling Regulates Metastasis of Chemoresistant Melanoma Cells by a Lymphatic Metastatic Niche

Kim M1¹, Koh YJ, Kim KE, Koh BI, Nam DH, Alitalo K, Kim I, Koh GY.

Treatment of atypical meningioma

Mol Cells. 2010 Nov;30(5):403-8. doi: 10.1007/s10059-010-0122-z. Epub 2010 Aug 31.

The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells

Park HJ1¹, Kim JK, Jeon HM, Oh SY, Kim SH, Nam DH, Kim H.

Exp Ther Med. 2010 Nov;1(6):943-946. Epub 2010 Aug 26.

Schedule-dependent synergistic effect of rituximab on methotrexate chemotherapy against lymphoma of the central nervous system

Jin J1¹, Joo KM, Nam Y, Kim DH, Lee SJ, Jo MY, Jin Y, Kim HS, Seo SW, Kim SJ, Nam DH, Kim WS.

Cancer Cell. 2010 Aug 9;18(2):171-84. doi: 10.1016/j.ccr.2010.07.001.

Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage

Koh YJ1¹, Kim HZ, Hwang SI, Lee JE, Oh N, Jung K, Kim M, Kim KE, Kim H, Lim NK, Jeon CJ, Lee GM, Jeon BH, Nam DH, Sung HK, Nagy A, Yoo OJ, Koh GY.

BMC Cancer. 2010 Aug 13;10:424. doi: 10.1186/1471-2407-10-424.

Impact of adjuvant chemotherapy for gliomatosis cerebri

Kong DS1¹, Kim ST, Lee JI, Suh YL, Lim do H, Kim WS, Kwon KH, Park K, Kim JH, Nam DH.

Neuro Oncol. 2010 Mar;12(3):289-96. doi: 10.1093/neuonc/nop030. Epub 2010 Jan 11.

Phase II trial of low-dose continuous (metronomic) treatment of temozolomide for recurrent glioblastoma

Kong DS1¹, Lee JI, Kim JH, Kim ST, Kim WS, Suh YL, Dong SM, Nam DH.

Clin Neurol Neurosurg. 2009 Nov;111(9):748-51. doi: 10.1016/j.clineuro.2009.07.014. Epub 2009 Aug 28.

Efficacy of temozolomide as adjuvant chemotherapy after postsurgical radiotherapy alone for glioblastomas

Rhee DJ1¹, Kong DS, Kim WS, Park KB, Lee JI, Suh YL, Song SY, Kim ST, Lim DH, Park K, Kim JH, Nam DH.

Clin Neurol Neurosurg. 2009 Oct;111(8):679-82. doi: 10.1016/j.clineuro.2009.06.013. Epub 2009 Jul 28.

Clinical outcome of concomitant chemoradiotherapy followed by adjuvant temozolomide therapy for glioblastaomas: Single-center experience

Jeon HJ1¹, Kong DS, Park KB, Lee JI, Park K, Kim JH, Kim ST, Lim do H, Kim WS, Nam DH.

Cell Stem Cell. 2009 May 8;4(5):440-52. doi: 10.1016/j.stem.2009.03.003.

SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma

Son MJ1¹, Woolard K, Nam DH, Lee J, Fine HA.

Mol Ther. 2009 Mar;17(3):570-5. doi: 10.1038/mt.2008.290. Epub 2009 Jan 6.

Human Neural Stem Cells Can Target and Deliver Therapeutic Genes to Breast Cancer Brain Metastases

Joo KM1¹, Park IH, Shin JY, Jin J, Kang BG, Kim MH, Lee SJ, Jo MY, Kim SU, Nam DH.

Cancer. 2009 Jan 1;115(1):140-8. doi: 10.1002/cncr.23972.

Prognostic Significance of c-Met Expression in Glioblastomas

Kong DS1¹, Song SY, Kim DH, Joo KM, Yoo JS, Koh JS, Dong SM, Suh YL, Lee JI, Park K, Kim JH, Nam DH.

Int J Oncol. 2008 Oct;33(4):705-12.

Response of brain specific microenvironment to P-glycoprotein inhibitor: An important factor determining therapeutic effect of P-glycoprotein inhibitor on brain metastatic tumors

Joo KM1¹, Song SY, Park K, Kim MH, Jin J, Kang BG, Jang MJ, Lee GS, Kim MS, Nam DH.

Lab Invest. 2008 Aug;88(8):808-15. doi: 10.1038/labinvest.2008.57. Epub 2008 Jun 16.

Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas

Joo KM1¹, Kim SY, Jin X, Song SY, Kong DS, Lee JI, Jeon JW, Kim MH, Kang BG, Jung Y, Jin J, Hong SC, Park WY, Lee DS, Kim H, Nam DH.

Genes Dev. 2008 Aug 1;22(15):2028-33. doi: 10.1101/gad.1668708.

Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling

Jeon HM1¹, Jin X, Lee JS, Oh SY, Sohn YW, Park HJ, Joo KM, Park WY, Nam DH, DePinho RA, Chin L, Kim H.

Clin Cancer Res. 2008 Jul 1;14(13):4059-66. doi: 10.1158/1078-0432.CCR-07-4039.

Activation of Notch signaling in a xenograft model of brain metastasis

Nam DH1¹, Jeon HM, Kim S, Kim MH, Lee YJ, Lee MS, Kim H, Joo KM, Lee DS, Price JE, Bang SI, Park WY.

J Clin Neurosci. 2008 Jun;15(6):721-2; author reply 722-3. doi: 10.1016/j.jocn.2007.08.031. Epub 2008 Apr 10.

Reply to letter regarding Tc-99m-Tetrofosmin SPECT for the assessment of meningioma malignancy

Alexiou GA¹, Tsiouris S, Goussia A, Polyzoidis KS, Fotopoulos AD, Kyritsis AP.

Cancer. 2008 May 1;112(9):2046-51. doi: 10.1002/cncr.23402.

Efficacy of stereotactic radiosurgery as a salvage treatment for recurrent malignant gliomas

Kong DS1¹, Lee JI, Park K, Kim JH, Lim DH, Nam DH.

Mol Med Rep. 2008 May-Jun;1(3):343-6.

Antitumor activity of ZD6474 in a metastatic orthotopic brain tumor model

Kong DS1¹, Kim MH, Jeon JW, Kim SY, Kim MS, Joo KM, Park K, Nam DH.

Oncol Rep. 2008 Mar;19(3):639-43.

The progression of gliomas is associated with cancer stem cell phenotype

Kong DS1¹, Kim MH, Park WY, Suh YL, Lee JI, Park K, Kim JH, Nam DH.

Oncol Rep. 2008 Jan;19(1):17-23.

Oral paclitaxel chemotherapy for brain tumors: Ideal combination treatment of paclitaxel and P-glycoprotein inhibitor

Joo KM1¹, Park K, Kong DS, Song SY, Kim MH, Lee GS, Kim MS, Nam DH.

J Clin Neurosci. 2007 Aug;14(8):747-53. Epub 2007 May 17.

Relationship between malignant subtypes of meningioma and clinical outcome

Ko KW1¹, Nam DH, Kong DS, Lee JI, Park K, Kim JH.

Headache. 2007 Feb;47(2):199-203.

Atypical spontaneous intracranial hypotension (SIH) with nonorthostatic headache

Kong DS1¹, Park K, Nam DH, Lee JI, Kim ES, Kim JS, Hong SC, Shin HJ, Eoh W, Kim JH.

J Phys Chem B. 2012 Nov 8;116(44):13228-38. doi: 10.1021/jp3032918. Epub 2012 Oct 30.

Development of a T-1 contrast agent for magnetic resonance imaging using MnO nanoparticles

L?tourneau M1¹, Tremblay M, Faucher L, Rojas D, Chevallier P, Gossuin Y, Lagueux J, Fortin MA.

J Neurosurg. 2006 Dec;105 Suppl:139-43.

Preservation of quality of life by preradiotherapy stereotactic radiosurgery for unresectable glioblastoma multiforme

Kong DS1¹, Nam DH, Lee JI, Park K, Kim JH.

Oncol Rep. 2006 Nov;16(5):1117-21.

A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomide-refractory glioblastoma

Kong DS1¹, Lee JI, Kim WS, Son MJ, Lim do H, Kim ST, Park K, Kim JH, Eoh W, Nam DH.

Oncol Rep. 2006 Jul;16(1):33-9.

Metronomic treatment of temozolomide inhibits tumor cell growth through reduction of angiogenesis and augmentation of apoptosis in orthotopic models of gliomas

Kim JT1¹, Kim JS, Ko KW, Kong DS, Kang CM, Kim MH, Son MJ, Song HS, Shin HJ, Lee DS, Eoh W, Nam DH.

Int J Oncol. 2006 Jun;28(6):1385-92.

Synergistic effect and condition of pegylated interferon a with paclitaxel on glioblastoma

Son MJ1¹, Song HS, Kim MH, Kim JT, Kang CM, Jeon JW, Park SY, Kim YJ, Groves MD, Park K, Kim JH, Nam DH.

Oncol Rep. 2006 May;15(5):1163-8.

Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model

Lee JI1¹, Itasaka S, Kim JT, Nam DH.

Int J Oncol. 2006 Jan;28(1):53-9.

Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model

Son MJ1¹, Kim JS, Kim MH, Song HS, Kim JT, Kim H, Shin T, Jeon HJ, Lee DS, Park SY, Kim YJ, Kim JH, Nam DH.

Oncol Rep. 2006 Jan;15(1):7-13.

Combination celecoxib and temozolomide in C6 rat glioma orthotopic model

Kang SG1¹, Kim JS, Park K, Kim JS, Groves MD, Nam DH.

Neurol Med Chir (Tokyo). 2005 May;45(5):232-8; discussion 238-9.

Clinical and radiological prognostic factors of anaplastic oligodendroglioma treated by combined therapy

Kang SG1¹, Kim JH, Nam DH, Park K.

Oncol Rep. 2004 Apr;11(4):863-9.

Expression of VEGF and brain specific angiogenesis inhibitor-1 in glioblastoma: prognostic significance

Nam DH1¹, Park K, Suh YL, Kim JH.

Oncol Rep. 2004 Feb;11(2):263-8.

Intracranial inhibition of glioma cell growth by cyclooxygenase-2 inhibitor celecoxib

Nam DH1¹, Park K, Park C, Im YH, Kim MH, Lee S, Hong SC, Shin HJ, Kim JH, Eoh W, McDonnell TJ.

Neurosci Lett. 2001 Oct 12;312(1):41-4.

Expression of interleukin-1 beta in lipopolysaccharide stimulated monocytes derived from patients with aneurysmal subarachnoid hemorrhage is correlated with cerebral vasospasm

Nam DH1¹, Kim JS, Hong SC, Lee WH, Lee JI, Shin HJ, Park K, Eoh W, Han DH, Kim JH.

Exp Mol Med. 2001 Sep 30;33(3):111-6.

Clinical significance of molecular genetic changes in sporadic invasive pituitary adenomas

Nam DH1¹, Song SY, Park K, Kim MH, Suh YL, Lee JI, Kim JS, Hong SC, Shin HJ, Park K, Eoh W, Kim JH.

Int J Oncol. 2001 Jan;18(1):111-6.

The detection of p53 gene mutation using a microdissection technique in primary intracranial germ cell tumors

Kim SK1¹, Cho BK, Paek SH, Hong SJ, Kim HS, Hong SY, Choe G, Chi JG, Nam DH, Wang KC.

J Korean Med Sci. 2000 Aug;15(4):452-6.

The effect of isochromosome 17q presence, proliferative and apoptotic indices, expression of c-erbB-2, bcl-2 and p53 proteins on the prognosis of medulloblastoma

Nam DH1¹, Wang KC, Kim YM, Chi JG, Kim SK, Cho BK.

Neurosci Lett. 2000 Mar 31;283(1):45-8.

Vascular endothelial growth factor expression under ischemic stress in human meningiomas

Park K1¹, Kim JH, Nam DH, Lee JI, Kim JS, Hong SC, Shin HJ, Eoh W, Park K.

Childs Nerv Syst. 1999 Apr;15(4):185-91.

Treatment of intracranial nongerminomatous malignant germ cell tumor in children: the role of each treatment modality

Nam DH1¹, Cho BK, Shin HJ, Ahn HS, Kim IH, Wang KC.

Childs Nerv Syst. 1999 Apr;15(4):179-84.

A simple method of predicting hormonal outcome in children with intracranial germinoma

Nam DH1¹, Wang KC, Shin CH, Yang SW, Cho BK.