Departments

Pathology and Translational Genomics

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Pathology and Translational Genomics

Evolving pathology: Translational Genomics and AI-powered Digital Pathology

The Department of Pathology and Translational Genomics supports patient care through accurate and timely pathological diagnoses, while also contributing to cutting-edge research and the training of excellent medical professionals through diverse research initiatives and educational programs.

We pursue continuous research on human pathological tissues essential for medical research, and strive to enhance research outcomes by incorporating the latest molecular pathology techniques and digital pathology, integrated with artificial intelligence.

Aligned with the philosophy of Samsung Medical Center-promoting medical innovation for patient happiness- we remain committed to our patients through accurate diagnosis, pioneering translational research in precision medicine, and the development of AI-powered diagnostic systems based on digital pathology.

Molecular pathology

One of our department's key strengths lies in molecular pathology, where we lead the field in Korea with cutting-edge technologies and expertise. We analyze DNA and RNA extracted from patient tissues to detect genetic abnormalities that inform diagnosis and treatment.

In the era of precision medicine, genomic biomarkers are essential for predicting drug response, and demand for molecular testing is growing rapidly. Recognizing this trend early, we were the first in Korea to implement targeted next-generation sequencing (NGS) in 2017 and have remained at the forefront of this field.

We offer high-quality molecular diagnostics with rapid turnaround times, including Sanger sequencing for specific genes, microsatellite instability testing, targeted NGS, methylation-specific PCR, and fluorescence in situ hybridization (FISH).

Digital Pathology

Another core strength of our department is digital pathology, where we have pioneered the integration of digital imaging and Al-based diagnostics in Korea.

Digital pathology revolutionizes traditional microscopy by digitizing glass slides for viewing, sharing, and interpretation on computer workstations. This system enables remote consultations, Al-assisted analysis, and seamless workflow management from specimen receipt to final diagnosis - enhancing efficiency, accuracy, and scalability.

In 2019, we became the first in Korea to implement a fully operational digital pathology system, which is now used routinely for both diagnostics and research - solidifying our leadership in the digital transformation of pathology.