Fatigue

Fatigue is a persistent feeling of tiredness, weakness, or lack of energy that does not improve with adequate rest. It may affect physical stamina, concentration, or emotional resilience. Unlike ordinary tiredness, fatigue can interfere with daily functioning and may signal an underlying health problem.

• Lifestyle factors: Poor sleep quality, irregular sleep schedule, lack of exercise, high stress, poor diet.
• Medical conditions:

Anemia, thyroid disorders, diabetes

Chronic infections such as mononucleosis or hepatitis

Heart failure, chronic lung disease, cancer

• Mental health: Depression, anxiety, burnout, post-traumatic stress disorder.
• Medications: Sedatives, antihistamines, blood pressure drugs, chemotherapy.
• Risk factors: Shift work, excessive caffeine or alcohol use, older age, chronic illnesses, long-term stress.

See a doctor if fatigue is persistent, unexplained, or severe, or if it is accompanied by symptoms such as:

• Fever, unexplained weight loss, or night sweats
• Chest pain or shortness of breath
• Significant mood changes or suicidal thoughts
• New fatigue after cancer treatment or other major illness

Evaluation may include physical exam, lab tests, and review of medications and lifestyle.