Rheumatology
Cha, Hoon Suk
95 AppointmentAssociate Professor of Medicine, Sungkyunkwan Universitiy School of Medicine
Speciality Interests
Spondyloarthoropathies
Gout
Systemic lupus erythematosus
Schedule
05 | THU 01 |
FRI 02 |
MON 05 |
TUE 06 |
WEN 07 |
---|---|---|---|---|---|
AM | available | ||||
PM |
Medical School
Seoul National University College of Medicine
Specialty Training
Fellowship | Samsung Medical Center | |
---|---|---|
Residency | Seoul National University Hospital | |
Internship | Seoul National University Hospital |
Other Education
Visiting Professor, UCSD, San Diego, CA, USA
Participation in Academic Societies
and Research
Member of Korean Association of Internal Medicine
Member of Korean Rheumatology Association
Member of American College of Rheumatology
Thesis
SCI REP-UK 2021 10.1038/s41598-021-91320-1
Selective estrogen receptor modulator lasofoxifene suppresses spondyloarthritis manifestation and affects characteristics of gut microbiota in zymosan-induced SKG mice
CLIN EXP RHEUMATOL 2021
Factors associated with radiographic progression in patients with Takayasu's arteritis
THER ADV MUSCULOSKELET DIS 2021 10.1177/1759720X21993253
How much does fat mass change affect serum uric acid levels among apparently clinically healthy Korean men?
SCI REP-UK 2020 10.1038/s41598-020-75352-7
Machine learning to predict early TNF inhibitor users in patients with ankylosing spondylitis
MEDICINA-LITHUANIA 2020 10.3390/medicina56100501
Increased Overall Heart Rate Irregularity Risk by Hyperuricemia in the General Population Results from the Korean National Health and Nutrition Examination Survey
CLIN EXP RHEUMATOL 2020
Variation in the synovial fluid metabolome according to disease activity of rheumatoid arthritis
PLoS One 2020 10.1371/journal.pone.0230072
Systematic re-evaluation of the long-used standard protocol of urease-dependent metabolome sample preparation
KOREAN JOURNAL OF INTERNAL MEDICINE 2020 10.3904/kjim.2018.137
Simplified disease activity changes in real-world practice: a nationwide observational study of seropositive rheumatoid arthritis patients with moderate-to-high disease activity
SCI REP-UK 2019 10.1038/s41598-019-55514-y
Association between anemia and hyperuricemia: results from the Korean National Health and Nutrition Examination Survey
SCI REP-UK 2019 10.1038/s41598-019-50574-6
Risk factors for immune-related adverse events associated with anti-PD-1 pembrolizumab
KOREAN JOURNAL OF INTERNAL MEDICINE 2019 10.3904/kjim.2017.159
Efficacy and safety of tocilizumab in Korean patients with active rheumatoid arthritis
J CLIN MED 2019 10.3390/jcm8060837
Women with Metabolic Syndrome and General Obesity Are at a Higher Risk for Significant Hyperuricemia Compared to Men
INT J RHEUM DIS 2019 10.1111/1756-185X.13521
Efficacy and safety of add-on tacrolimus versus leflunomide in rheumatoid arthritis patients with inadequate response to methotrexate
ARTHRITIS RES THER 2019 10.1186/s13075-019-1910-2
Long-term efficacy, safety and immunogenicity in patients with rheumatoid arthritis continuing on an etanercept biosimilar (LBEC0101) or switching from reference etanercept to LBEC0101: an open-label extension of a phase III multicentre, randomised, double-blind, parallel-group study
LUPUS 2019 10.1177/0961203319843343
Hydroxychloroquine treatment during pregnancy in lupus patients is associated with lower risk of preeclampsia
J KOREAN MED SCI 2018 10.3346/jkms.2018.33.e346
Treat-to-Target Strategy for Asian Patients with Early Rheumatoid Arthritis: Result of a Multicenter Trial in Korea
KOREAN JOURNAL OF INTERNAL MEDICINE 2018 10.3904/kjim.2016.213
Rapid onset of efficacy predicts response to therapy with certolizumab plus methotrexate in patients with active rheumatoid arthritis
JOINT BONE SPINE 2018 10.1016/j.jbspin.2017.11.008
Spondyloarthritis features in zymosan-induced SKG mice
INT J RHEUM DIS 2018 10.1111/1756-185X.13013
Prevalence of co-morbidities and evaluation of their monitoring in Korean patients with rheumatoid arthritis: comparison with the results of an international, cross-sectional study (COMORA)
J KOREAN MED SCI 2018 10.3346/jkms.2018.33.e168
Disease Characteristics and Change in Arthritis Activity according to Treatment in Hepatitis B Surface Antigen-positive Rheumatoid Arthritis Patients: a Retrospective Chart Review Study
INT J RHEUM DIS 2018 10.1111/1756-185X.13270
Effect of tumor necrosis factor inhibitors on spinal radiographic progression in patients with ankylosing spondylitis
JOINT BONE SPINE 2018 10.1016/j.jbspin.2017.05.019
Potential metabolomic biomarkers for reliable diagnosis of Behcet's disease using gas chromatography/time-of-flight-mass spectrometry
KOREAN JOURNAL OF INTERNAL MEDICINE 2018 10.3904/kjim.2016.042
Drug survival of tumor necrosis factor a inhibitors in patients with ankylosing spondylitis in Korea
SEMIN ARTHRITIS RHEU 2018 10.1016/j.semarthrit.2017.08.007
Persistence of biologic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: An analysis of the South Korean National Health Insurance Database
INT J RHEUM DIS 2017 10.1111/1756-185X.13194
Clinical characteristics and outcomes of 61 patients with chronic periaortitis including IgG4-related and non-IgG4-related cases
INT J MOL SCI 2017 10.3390/ijms18112309
Urinary Metabolomic Profiling to Identify Potential Biomarkers for the Diagnosis of Behcet's Disease by Gas Chromatography/Time-of-Flight-Mass Spectrometry
ANN LAB MED 2017 10.3343/alm.2017.37.6.540
Novel 4-bp Intronic Deletion (c.1560+3_1560+6del) in LEMD3 in a Korean Patient With Osteopoikilosis
PLoS One 2017 10.1371/journal.pone.0186141
Comorbidities and health-related quality of life in Koreans with knee osteoarthritis: Data from the Korean National Health and Nutrition Examination Survey (KNHANES)
JOINT BONE SPINE 2017 10.1016/j.jbspin.2016.05.018
Metabolite profiles of synovial fluid change with the radiographic severity of knee osteoarthritis
ARTHRITIS RES THER 2017 10.1186/s13075-017-1407-9
Estrogen attenuates the spondyloarthritis manifestations of the SKG arthritis model
Rev Bras Reumatol 2017 10.1016/j.rbr.2016.10.001
Higher body mass index and anti-drug antibodies predict the discontinuation of anti-TNF agents in Korean patients with axial spondyloarthritis
KOREAN JOURNAL OF INTERNAL MEDICINE 2017 10.3904/kjim.2015.364
Impact of early diagnosis on functional disability in rheumatoid arthritis
Ann Lab Med. 2017 May;37(3):240-247. doi: 10.3343/alm.2017.37.3.240.
Performance of an Automated Fluorescence Antinuclear Antibody Image Analyzer
PLoS One. 2017 Apr 19;12(4):e0176260. doi: 10.1371/journal.pone.0176260. eCollection 2017.
Comorbidities of rheumatoid arthritis: Results from the Korean National Health and Nutrition Examination Survey
J Korean Med Sci. 2017 Mar;32(3):522-527. doi: 10.3346/jkms.2017.32.3.522.
Frequency and Clinical Characteristics of Hydroxychloroquine Retinopathy in Korean Patients with Rheumatologic Diseases
Mod Rheumatol. 2017 Jan;27(1):35-41. doi: 10.1080/14397595.2016.1176310. Epub 2016 May 4.
What factors affect discordance between physicians and patients in the global assessment of disease activity in rheumatoid arthritis?
Korean J Intern Med. 2017 Jan;32(1):158-164. doi: 10.3904/kjim.2015.229. Epub 2016 Mar 25.
Characteristics of hip involvement in patients with ankylosing spondylitis in Korea
Osteoporos Int. 2017 Jan;28(1):231-237. doi: 10.1007/s00198-016-3703-7. Epub 2016 Aug 10.
Bone-density testing interval and transition to osteoporosis in patients with rheumatoid arthritis
Joint Bone Spine. 2016 Dec;83(6):707-713. doi: 10.1016/j.jbspin.2015.11.009. Epub 2016 Apr 25.
GC/TOF-MS-based metabolomic profiling in cultured fibroblast-like synoviocytes from rheumatoid arthritis
J Korean Med Sci. 2016 Dec;31(12):1907-1913. doi: 10.3346/jkms.2016.31.12.1907.
Factors Contributing to Discordance between the 2011 ACR/EULAR Criteria and Physician Clinical Judgment for the Identification of Remission in Patients with Rheumatoid Arthritis
Clin Exp Rheumatol. 2016 Sep-Oct;34(6 Suppl 102):S64-S71. Epub 2016 Jul 26.
Efficacy of tocilizumab therapy in Korean patients with adult-onset Still's disease: a multicentre retrospective study of 22 cases
PLoS One. 2016 Oct 13;11(10):e0164591. doi: 10.1371/journal.pone.0164591. eCollection 2016.
Evaluation of Audiometric Test Results to Determine Hearing Impairment in Patients with Rheumatoid Arthritis: Analysis of Data from the Korean National Health and Nutrition Examination Survey
Ann Hematol. 2016 Jan;95(2):325-35. doi: 10.1007/s00277-015-2523-8. Epub 2015 Oct 10.
Clinical significance of bone marrow hemophagocytosis in adult patients with malignancy and non-malignancy-induced hemophagocytic lymphohistiocytosis
Heart Vessels. 2016 Aug;31(8):1277-84. doi: 10.1007/s00380-015-0731-8. Epub 2015 Aug 13.
Comparison of clinical characteristics in patients with Takayasu arteritis with and without concomitant tuberculosis
Medicine (Baltimore). 2016 Jul;95(27):e4168. doi: 10.1097/MD.0000000000004168.
A case report of severely damaged hip joint caused by SAPHO syndrome treated with 2-stage total hip arthroplasty
Rheumatol Int. 2016 Apr;36(4):505-13. doi: 10.1007/s00296-016-3427-1. Epub 2016 Feb 6.
Mapping health assessment questionnaire disability index (HAQ-DI) score, pain visual analog scale (VAS), and disease activity score in 28 joints (DAS28) onto the EuroQol-5D (EQ-5D) utility score with the KORean Observational study Network for Arthritis (KORONA) registry data
PLoS One. 2015 Dec 30;10(12):e0145539. doi: 10.1371/journal.pone.0145539. eCollection 2015.
Metabolomic Elucidation of the Effects of Curcumin on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
Joint Bone Spine. 2015 Dec;82(6):473-4. doi: 10.1016/j.jbspin.2014.11.009. Epub 2015 Jul 14.
Body mass index and estrogen predict radiographic progression in the spine in ankylosing spondylitis
J Rheumatol. 2015 Nov;42(11):2075-81. doi: 10.3899/jrheum.141447. Epub 2015 Sep 1.
Factors Associated with the Use of Complementary and Alternative Medicine for Korean Patients with Rheumatoid Arthritis
PLoS One. 2015 Oct 16;10(10):e0141033. doi: 10.1371/journal.pone.0141033. eCollection 2015.
The Significance of Sensitive Interferon Gamma Release Assays for Diagnosis of Latent Tuberculosis Infection in Patients Receiving Tumor Necrosis Factor-alpha Antagonist Therapy
PLoS One. 2015 Aug 13;10(8):e0135856. doi: 10.1371/journal.pone.0135856. eCollection 2015.
A Comparative Metabolomic Evaluation of Behcet's Disease with Arthritis and Seronegative Arthritis Using Synovial Fluid
Int J Rheum Dis. 2015 Jul;18(6):661-8. doi: 10.1111/1756-185X.12458. Epub 2014 Sep 8.
Clinical characteristics of nonradiographic axial spondyloarthritis in Korea: a comparison with ankylosing spondylitis
J Immunol. 2015 Jul 15;195(2):564-75. doi: 10.4049/jimmunol.1401661. Epub 2015 Jun 8.
Early Development in the Peritoneal Cavity of CD49d(high) Th1 Memory Phenotype CD4(+) T Cells with Enhanced B Cell Helper Activity
Int J Rheum Dis. 2015 Jun;18(5):514-23. doi: 10.1111/1756-185X.12501. Epub 2014 Dec 20.
A novel histone deacetylase 6-selective inhibitor suppresses synovial inflammation and joint destruction in a collagen antibody-induced arthritis mouse model
Korean J Intern Med. 2015 May;30(3):391-7. doi: 10.3904/kjim.2015.30.3.391. Epub 2015 Apr 29.
Predictive factors of radiographic progression in ankylosing spondylitis
Yonsei Med J. 2015 May;56(3):676-83. doi: 10.3349/ymj.2015.56.3.676.
Significance of Myositis Autoantibody in Patients with Idiopathic Interstitial Lung Disease
J Immunol Res. 2015;2015:487230. doi: 10.1155/2015/487230. Epub 2015 Apr 2.
Low Baseline Interleukin-17A Levels Are Associated with Better Treatment Response at 12 Weeks to Tocilizumab Therapy in Rheumatoid Arthritis Patients
Rheumatol Int. 2015 Apr;35(4):727-34. doi: 10.1007/s00296-014-3146-4. Epub 2014 Oct 8.
Effect of anti-tumor necrosis factor alpha treatment of rheumatoid arthritis and chronic kidney disease
PLoS One. 2015 Mar 6;10(3):e0119260. doi: 10.1371/journal.pone.0119260. eCollection 2015.
QuantiFERON-TB Gold In-Tube Assay for Screening Arthritis Patients for Latent Tuberculosis Infection before Starting Anti-Tumor Necrosis Factor Treatment
Korean J Intern Med. 2015 Mar;30(2):242-9. doi: 10.3904/kjim.2015.30.2.242. Epub 2015 Feb 27.
Clinical characteristics of male and female Korean patients with systemic lupus erythematosus: a comparative study
Clin Exp Rheumatol. 2015 Mar-Apr;33(2 Suppl 89):S-132-7. Epub 2015 May 26.
Gender differences in clinical and angiographic findings of patients with Takayasu arteritis
Invest Ophthalmol Vis Sci. 2014 Nov 25;56(1):396-402. doi: 10.1167/iovs.14-15138.
Macular Retinal Ganglion Cell-Inner Plexiform Layer Thickness in Patients on Hydroxychloroquine Therapy
Int J Rheum Dis. 2014 Nov;17(8):887-97. doi: 10.1111/1756-185X.12435. Epub 2014 Sep 29.
Pregnancy outcomes in patients with systemic lupus erythematosus: a retrospective review of 62 pregnancies at a single tertiary center in South Korea
Int J Rheum Dis. 2014 Jun;17(5):502-10. doi: 10.1111/1756-185X.12259. Epub 2013 Dec 14.
Clinical courses and predictors of outcomes in patients with monoarthritis: a retrospective study of 171 cases
PLoS One. 2014 Jun 2;9(6):e97501. doi: 10.1371/journal.pone.0097501. eCollection 2014.
Global Metabolite Profiling of Synovial Fluid for the Specific Diagnosis of Rheumatoid Arthritis from Other Inflammatory Arthritis
Joint Bone Spine. 2013 Dec;80(6):621-5. doi: 10.1016/j.jbspin.2013.02.009. Epub 2013 Apr 6.
A role for benzo[a]pyrene and Slug in invasive properties of fibroblast-like synoviocytes in rheumatoid arthritis: A potential molecular link between smoking and radiographic progression
Rheumatology (Oxford). 2013 Aug;52(8):1368-76. doi: 10.1093/rheumatology/ket147. Epub 2013 Apr 25.
The role of alpha-defensin-1 and related signal transduction mechanisms in the production of IL-6, IL-8 and MMPs in rheumatoid fibroblast-like synoviocytes
Mod Rheumatol. 2012 Nov;22(6):885-91. doi: 10.1007/s10165-012-0603-3. Epub 2012 Feb 11.
Prevalence of rheumatoid factor and parameters associated with rheumatoid factor positivity in Korean health screening subjects and subjects with hepatitis B surface antigen
Semin Arthritis Rheum. 2012 Aug;42(1):23-31. doi: 10.1016/j.semarthrit.2012.02.004. Epub 2012 Mar 31.
Do Patients with Elderly-Onset Rheumatoid Arthritis Have Severe Functional Disability
Rheumatol Int. 2012 Jul;32(7):1877-84. doi: 10.1007/s00296-011-1887-x. Epub 2011 Mar 27.
Outcome of reclassification of World Health Organization (WHO) class III under International Society of Nephrology-Renal Pathology Society (ISN-RPS) classification: retrospective observational study
Semin Arthritis Rheum. 2012 Jun;41(6):745-51. doi: 10.1016/j.semarthrit.2011.09.007. Epub 2011 Dec 9.
Korean Observational Study Network for Arthritis (KORONA): Establishment of a Prospective Multicenter Cohort for Rheumatoid Arthritis in South Korea
Inflammation. 2012 Apr;35(2):633-7. doi: 10.1007/s10753-011-9355-z.
Underexpression of TIM-3 and Blunted Galectin-9-Induced Apoptosis of CD4+T Cells in Rheumatoid Arthritis
Inflammation. 2012 Apr;35(2):474-83. doi: 10.1007/s10753-011-9336-2.
The Role of Raf Kinase Inhibitor Protein in Rheumatoid Fibroblast-like Synoviocytes Invasiveness and Cytokine and Matrix Metalloproteinase Expression
J Am Coll Cardiol. 2012 Feb 14;59(7):e13. doi: 10.1016/j.jacc.2011.04.055.
Polyarteritis Nodosa Involving Renal and Coronary Arteries
J Korean Med Sci. 2012 Jan;27(1):107-9. doi: 10.3346/jkms.2012.27.1.107. Epub 2011 Dec 19.
Correlation of DEFA1 Gene Copy Number Variation with Intestinal Involvement in Behcet's Disease
Joint Bone Spine. 2011 Dec;78(6):593-7. doi: 10.1016/j.jbspin.2011.01.012. Epub 2011 Mar 26.
Increased alpha-defensin-1 expression in Korean patients with Behcet's disease
Scand J Rheumatol. 2011;40(5):334-40. doi: 10.3109/03009742.2010.547871. Epub 2011 Mar 30.
Expression of human TIM-3 and its correlation with disease activity in rheumatoid arthritis
J Korean Med Sci. 2011 May;26(5):697-700. doi: 10.3346/jkms.2011.26.5.697. Epub 2011 Apr 21.
Extracellular High-Mobility Group Box 1 is Increased in Patients with Behcet's Disease with Intestinal Involvement
Pediatr Radiol. 2010 Sep;40(9):1572-5. doi: 10.1007/s00247-010-1628-4. Epub 2010 Mar 25.
MRI findings in Kirner deformity: normal insertion of the flexor digitorum profundus tendon without soft-tissue enhancement
Exp Mol Med. 2010 Jun 30;42(6):428-36.
Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide
Rheumatol Int. 2010 Apr;30(6):831-5. doi: 10.1007/s00296-009-1319-3. Epub 2009 Dec 17.
Behcet's disease associated with malignancy in Korea: a single center experience
Clin Ther. 2009 Dec;31(12):2860-72. doi: 10.1016/j.clinthera.2009.12.016.
Comparative Clinical Trial of S-Adenosylmethionine Versus Nabumetone for the Treatment of Knee Osteoarthritis: An 8-Week, Multicenter, Randomized, Double-Blind, Double-Dummy, Phase IV Study in Korean Patients
Rheumatol Int. 2009 Sep;29(11):1391-3. doi: 10.1007/s00296-009-0862-2. Epub 2009 Jan 25.
Treatment outcomes in patients with non-infectious aortic valvulitis undergoing aortic valve replacement: implication for the treatment of aortic valve involvement in Behcet's disease
Rheumatol Int. 2009 Apr;29(6):689-92. doi: 10.1007/s00296-008-0735-0. Epub 2008 Oct 9.
Ankylosing spondylitis in a patient with myelodysplastic syndrome: an association with HLA-B27 or coincidence
Clin Rheumatol. 2008 Nov;27(11):1455-8. doi: 10.1007/s10067-008-0951-8. Epub 2008 Jul 1.
Successful cyclophosphamide therapy with complete resolution of pulmonary artery aneurysm in Hughes-Stovin syndrome patient
Rheumatology (Oxford). 2008 Aug;47(8):1228-30. doi: 10.1093/rheumatology/ken162. Epub 2008 Jun 11.
Behcets disease associated with bone marrow failure in Korean patients: clinical characteristics and the association of intestinal ulceration and trisomy 8
Clin Rheumatol. 2008 Feb;27(2):201-5. Epub 2007 Jul 17.
Treatment of venous thrombosis associated with Behcet's disease: immunosuppressive therapy alone versus immunosuppressive therapy plus anticoagulation
Clin Exp Immunol. 2007 Jun;148(3):410-8. Epub 2007 Mar 15.
Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis
Clin Ther. 2007 May;29(5):862-73.
Assessment of comparative pain relief and tolerability of SK1306X compared with celecoxib in patients with rheumatoid arthritis: A 6-week, multicenter, randomized, double-blind, double-dummy, phase III, noninferiority clinical trial
J Rheumatol. 2007 Jan;34(1):16-9.
Tumor necrosis factor-alpha induces vascular endothelial growth factor-C expression in rheumatoid synoviocytes
Clin Immunol. 2005 Sep;116(3):217-24.
Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages (vol 116, pg 217, 2005)
Clin Immunol. 2005 Sep;116(3):217-24.
Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages
Immunology. 2005 Feb;114(2):272-9.
LIGHT is involved in the pathogenesis of rheumatoid arthritis by inducing the expression of pro-inflammatory cytokines and MMP-9 in macrophages
Ann Rheum Dis. 2004 Oct;63(10):1244-9.
Association of the oestrogen receptor a gene polymorphisms with disease onset in systemic lupus erythematosus
Rheumatol Int. 2004 Jul;24(4):207-11. Epub 2003 Jul 26.
Inhibitory effect of cyclo-oxygenase-2 inhibitor on the production of matrix metalloproteinases in rheumatoid fibroblast-like synoviocytes
Scand J Rheumatol. 2004;33(3):179-84.
Autoantibodies to glucose-6-phosphate isomerase are elevated in the synovial fluid of rheumatoid arthritis patients
Clin Exp Rheumatol. 2003 Sep-Oct;21(5):593-8.
Influence of hypoxia on the expression of matrix metalloproteinase-1,-3 and tissue inhibitor of metalloproteinase-1 in rheumatoid synovial fibroblasts
Exp Mol Med. 2003 Aug 31;35(4):310-6.
Detection of antibodies against glucose 6-phosphate isomerase in synovial fluid of rheumatoid arthritis using surface plasmon resonance (BIAcore)
Int J Clin Pharmacol Ther. 2001 Dec;39(12):539-45.
Comparison of the efficacy and safety of naproxen CR and nabumetone in the treatment of patients with osteoarthritis of the knee